Patents by Inventor Dmitri Rozanov

Dmitri Rozanov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human leucine zipper/trail recombinant polypeptides
    Patent number: 10131701
    Abstract: Disclosed are recombinant polypeptides that include human TRAIL sequences as well as human leucine zipper motifs as well as polynucleotides that encode the recombinant polypeptides, expression vectors that comprise the polynucleotides, pharmaceutical compositions comprising the polypeptides, and methods of using the pharmaceutical compositions for the treatment of cancer. Further disclosed are TRAIL sequences with stabilizing mutations and methods of expressing the disclosed polypeptides in E. coli.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: November 20, 2018
    Assignees: Oregon Health & Science University, Sanford Burnham Prebys Medical Discovery Institute
    Inventors: Dmitri Rozanov, Alexander Aleshin
  • HUMAN LEUCINE ZIPPER/TRAIL RECOMBINANT POLYPEPTIDES
    Publication number: 20160280761
    Abstract: Disclosed are recombinant polypeptides that include human TRAIL sequences as well as human leucine zipper motifs as well as polynucleotides that encode the recombinant polypeptides, expression vectors that comprise the polynucleotides, pharmaceutical compositions comprising the polypeptides, and methods of using the pharmaceutical compositions for the treatment of cancer. Further disclosed are TRAIL sequences with stabilizing mutations and methods of expressing the disclosed polypeptides in E. coli.
    Type: Application
    Filed: March 25, 2016
    Publication date: September 29, 2016
    Inventors: Dmitri Rozanov, Alexander Aleshin