Patents by Inventor Dmitri V. Gnatenko

Dmitri V. Gnatenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETECTING THROMBOCYTOSIS USING BIOMARKERS
    Publication number: 20120264633
    Abstract: The present invention relates to a method to determine the gene expression profile of thrombocytotic sensitive genes. The method comprises the following steps; obtaining hematologic samples from subjects in a training set, analyzing the obtained hematologic samples with a microarray, measuring the expression values of each gene on the microarray, performing analysis to identify differentially expressed genes in the training set among three cohorts of thrombocytosis, obtaining hematologic samples from subjects in an independent testing set, and validating the identity of the differentially expressed genes in the independent testing set among the three cohorts of thrombocytosis. The invention also relates to a method to distinguish thrombocytosis cohorts. The method includes the following steps; obtaining a hematologic sample from a subject, determining gene expression of a biomarker subset, analyzing gene expression of the biomarker subset, and classifying the subject into one of three cohorts.
    Type: Application
    Filed: September 20, 2010
    Publication date: October 18, 2012
    Inventors: Wadie F. Bahou, Dmitri V. Gnatenko
  • Hybrid adenovirus/adeno-associated virus vectors and methods of use thereof
    Patent number: 7563617
    Abstract: The invention provides recombinant vectors including adenovirus/adeno-associated virus (Ad/AAV) vectors and mini-adenovirus (mAd) vectors. Further, the invention provides cells containing these vectors, and methods for making and using the vectors and cells. The compositions and methods of the invention are useful in transferring nucleotide sequences of interest into a cell, including, but not limited to, in gene therapy applications.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: July 21, 2009
    Assignee: The Research Foundation Of State University of New York
    Inventors: Patrick Hearing, Wadie F. Bahou, Ziv Sandalon, Dmitri V. Gnatenko
  • Hybrid adenovirus/adeno-associated virus vectors and methods of use thereof
    Patent number: 6916635
    Abstract: The invention provides recombinant vectors including adenovirus/adeno-associated virus (Ad/AAV) vectors and mini-adenovirus (mAd) vectors. Further, the invention provides cells containing these vectors, and methods for making and using the vectors and cells. The compositions and methods of the invention are useful in transferring nucleotide sequences of interest into a cell, including, but not limited to, in gene therapy applications.
    Type: Grant
    Filed: February 12, 2001
    Date of Patent: July 12, 2005
    Assignee: The Research Foundation of State University of New York
    Inventors: Patrick Hearing, Wadie F. Bahou, Ziv Sandalon, Dmitri V. Gnatenko
  • Hybrid adenovirus/adeno-associated virus vectors and methods of use thereof
    Publication number: 20020102731
    Abstract: The invention provides recombinant vectors including adenovirus/adeno-associated virus (Ad/AAV) vectors and mini-adenovirus (mAd) vectors. Further, the invention provides cells containing these vectors, and methods for making and using the vectors and cells. The compositions and methods of the invention are useful in transferring nucleotide sequences of interest into a cell, including, but not limited to, in gene therapy applications.
    Type: Application
    Filed: February 12, 2001
    Publication date: August 1, 2002
    Applicant: The Research Foundation of State University of New York
    Inventors: Patrick Hearing, Wadie F. Bahou, Ziv Sandalon, Dmitri V. Gnatenko