Patents by Inventor Dmitriy KHODAKOV

Dmitriy KHODAKOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APPARATUS AND METHODS FOR MULTIPLEXED AMPLIFICATION AND DETECTION OF DNA USING CONVECTIONAL HEATING AND LABEL-FREE MICROARRAY
    Publication number: 20220048033
    Abstract: The disclosure describes apparatus and methods for multiplexed amplification and detection of nucleic acid targets in a sample. Embodiments of the present disclosure include a mechanical system configured to provide loading, vertical positioning and clamping of a chip; a thermal control system configured to maintain distinct temperatures of the chip, and an optical fluorescence imaging system.
    Type: Application
    Filed: September 13, 2019
    Publication date: February 17, 2022
    Applicant: William Marsh Rice University
    Inventors: David Yu ZHANG, Dmitriy A. KHODAKOV, Xuemeng ZHANG
  • SURFACE-BASED DETECTION OF NUCLEIC ACID IN A CONVECTION FLOW FLUIDIC DEVICE
    Publication number: 20200324292
    Abstract: The present disclosure provides methods, composition and devices for performing convection-based PCR and non-enzymatic amplification of nucleic acid sequences. Techniques and reagents employed in these methods include toehold probes, strand displacement reactions, Rayleigh-Benard convection, temperature gradients, multiplexed amplification, multiplexed detection, and DNA functionalization, in open and closed systems, for use in nucleic tests and assays.
    Type: Application
    Filed: March 28, 2017
    Publication date: October 15, 2020
    Applicant: William Marsh Rice University
    Inventors: Dmitriy KHODAKOV, David ZHANG