Patents by Inventor Dmitriy Minond

Dmitriy Minond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR TREATING RHEUMATOID ARTHRITIS (RA) USING AN ENZYME-AND SUBSTRATE SELECTIVE EXOSITE INHIBITOR OF A DISINTEGRIN AND METALLOPROTEASE 10 (ADAM10)
    Publication number: 20250177333
    Abstract: Methods for treating conditions of immune disfunction, such as rheumatoid arthritis (RA), use enzyme- and substrate-selective exosite inhibitors of A disintegrin and metalloprotease 10 (ADAM10), such as N-(3-chloro-4-methylphenyl)-2-[2-(3-methoxybenzoyl) hydrazinyl]-2-oxoacetamide (PubChem CID3117694). The method for treating a condition of immune disfunction in a subject in need thereof includes: providing a composition including a therapeutically effective dosage of a modulator of A disintegrin and metalloprotease 10 (ADAM10) and at least one acceptable pharmaceutical carrier; and administering the composition to the subject, thereby treating the condition of immune disfunction in the subject by modulating ADAM10.
    Type: Application
    Filed: March 8, 2023
    Publication date: June 5, 2025
    Applicant: Nova Southeastern University
    Inventor: Dmitriy Minond
  • Methods for treating melanoma using small molecules
    Patent number: 11149028
    Abstract: The invention provides methods for treating cancers, such as melanoma and/or metastatic melanoma, using compounds that interact with and/or inhibit cellular proteins lamin A/C, ATP-dependent RNA helicase DDX1 (DDX1), heterogeneous nuclear ribonuclear protein H1/H2 (hnRNP H2), and/or heterogeneous nuclear ribonuclear protein A2/B1 (hnRNP A2/B1). The invention additionally provides a method for identifying compounds active against melanoma cells.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: October 19, 2021
    Assignees: Nova Southeastern University, Auburn University, Florida Atantic University Board Of Trustees, Torrey Pines Institute for Molecular Studies
    Inventors: Dmitriy Minond, Gregg B. Fields, Marcello Giulianotti
  • METHODS FOR TREATING MELANOMA USING SMALL MOLECULES AND SMALL INTERFERING RNA (siRNA)
    Publication number: 20200062736
    Abstract: The invention provides methods for treating cancers, such as melanoma and/or metastatic melanoma, using compounds that interact with and/or inhibit cellular proteins lamin A/C, ATP-dependent RNA helicase DDX1 (DDX1), heterogeneous nuclear ribonuclear protein H1/H2 (hnRNP H2), and/or heterogeneous nuclear ribonuclear protein A2/B1 (hnRNP A2/B1). The invention additionally provides a method for identifying compounds active against melanoma cells.
    Type: Application
    Filed: December 15, 2017
    Publication date: February 27, 2020
    Applicants: NOVA SOUTHEASTERN UNIVERSITY, AUBURN UNIVERSITY, FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES, TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
    Inventors: Dmitriy Minond, Gregg B. Fields, Marcello Giulianotti
  • Compounds and methods of treating neurological disorders
    Patent number: 9994536
    Abstract: Embodiments of the present disclosure provide for compositions including a compound, pharmaceutical compositions including the compound, methods of treatment of a disease or related condition (e.g., neurological disease on condition), methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: June 12, 2018
    Assignee: Torrey Pines Institute for Molecular Studies
    Inventors: Madepalli K. Lakshmana, Adel Nefzi, Richard Houghten, Dmitriy Minond
  • COMPOUNDS AND METHODS OF TREATING NEUROLOGICAL DISORDERS
    Publication number: 20170121296
    Abstract: Embodiments of the present disclosure provide for compositions including a compound, pharmaceutical compositions including the compound, methods of treatment of a disease or related condition (e.g., neurological disease on condition), methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: May 1, 2015
    Publication date: May 4, 2017
    Applicant: TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
    Inventors: MADEPALLI K. LAKSHMANA, ADEL NEFZI, RICHARD HOUGHTEN, DMITRIY MINOND
  • COMPOUNDS AND METHODS OF TREATING NEUROLOGICAL DISORDERS
    Publication number: 20150315179
    Abstract: Embodiments of the present disclosure provide for compositions including a compound, pharmaceutical compositions including the compound, methods of treatment of a disease or related condition (e.g., neurological disease on condition), methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: April 30, 2015
    Publication date: November 5, 2015
    Inventors: Madepalli K. Lakshmana, Adel Nefzi, Richard Houghten, Dmitriy Minond