Abstract: The present invention relates to the use of an esterase for monitoring and/or tracking the synthesis of a protein, polypeptide or peptide in a cell-free translation system or in an in vivo expression system in which the synthesis of a protein, polypeptide or peptide can occur, wherein said monitoring and/or tracking comprises the detection of the function of said esterase. The present invention further relates to a vector comprising a nucleic acid molecule coding for an esterase and expressing an esterase fusionprotein. Moreover, the present invention relates to a vector comprising a nucleic acid molecule coding for an esterase and comprising in frame at least one multiple cloning site for a further protein/polypeptide/peptide, to be expressed in form of a fusion protein comprising said esterase (esterase activity) and said further proteinaceous peptide structure. The present invention also provides for a protein, polypeptide or peptide encoded by the vectors of the present invention.

Abstract: Light emitting diodes are prepared with specialized packages which provide a dosing feature with respect to a phosphor wavelength converting medium. Elements of the device package form a specially shaped cavity when coupled together. The shape and size of the cavity operates to control the dosing of phosphor spiked medium of soft gel. The gel fills the cavity such that light emitted from a semiconductor die is exposed to a similar cross section independent of the exact direction of light propagation. In this way, ‘white’ LED systems are formed from blue emitting diodes as highly controlled phosphor dosing permits precise amounts of blue light to be converted to yellow light without problems with angular uniformity observed in competing technologies.

Abstract: Light emitting diodes are prepared with specialized packages which provide a dosing feature with respect to a phosphor wavelength converting medium. Elements of the device package form a specially shaped cavity when coupled together. The shape and size of the cavity operates to control the dosing of phosphor spiked medium of soft gel. The gel fills the cavity such that light emitted from a semiconductor die is exposed to a similar cross section independent of the exact direction of light propagation. In this way, ‘white’ LED systems are formed from blue emitting diodes as highly controlled phosphor dosing permits precise amounts of blue light to be converted to yellow light without problems with angular uniformity observed in competing technologies.

Abstract: A Peltier effect cooling device is formed in combination with an electronic device to form a unique thermal and electrical relationship. An electronic device to be cooled is placed in a serial electrical relationship between at least two thermoelectric couples while simultaneously being in thermal contact with a cold side of the cooler arrangement. The same current which produces the thermoelectric effect in the Peltier thermocouples also drives the electronic device. A balanced effect results as a higher driving current through the electronic device causes greater heating, it is offset by the added cooling due to a greater current in the thermocouples. In addition, a unique spatial arrangement provides improved heat distribution and transfer to a heat sink. Due to the unique shapes of Peltier elements, heat is pulled radially from a heat generating source and distributed at a peripheral region.