Abstract: A hybrid NIRF/IVUS imaging probe containing i) a spatially-truncated optical lens a substantially-planar surface of which is inclined with respect to an axis to reflect light, transmitted between proximal and distal ends of the probe, internally into a body of the lens, and ii) an acoustic transducer disposed sequentially with the optical lens on the axis of the probe while, at the same time, the optical and electrical members of the probe transmitting the radiative and mechanical energies (which the probe exchanges with a target bodily vessel) are parallel to one another within the housing of the probe. A method for operating the probe resulting in formation of spatially co-registered optical and acoustic images of the target. Related imaging system and computer-program product.

Abstract: A solution is proposed for testing a luminescence imaging apparatus (105). A corresponding testing device (110) comprises one or more seats (320) and one or more containers (325), each filled with a liquid comprising at least one luminescence substance and accommodated in a corresponding seat (320); the seats (320) have corresponding windows (330) for imaging the luminescence substance of the containers (325) accommodated therein. The seats (320) are slanted with respect to a resting surface (310) of the testing device (110). A holder (305) for use in the testing device (100) is further provided. A luminescence imaging apparatus (105) for use with the testing device (110) is also proposed. Moreover, a system (100) comprising a luminescence imaging apparatus (105) and this testing device (110) is proposed.

Abstract: A solution is proposed for imaging a body-part (103) of a patient (106) with an endoscopic system (100). A corresponding method (500) comprises acquiring (509-515) two sequences of images with different probes (127n,127b), of corresponding endoscopic units (115m,115b), that are movable therebetween. Corresponding images of each pair in the two sequences are registered (518-584), for example, according to corresponding motions of their probes (127n,127b) that are estimated independently each according to the corresponding images. A method (800) is also proposed for training a neural network (439) that may be used to register the images. Corresponding computer programs (400;700) and computer program products for operating the endoscopic system (100) and for training the neural network (439) are proposed.

Abstract: A solution is proposed for testing a luminescence imaging apparatus (105). A corresponding method (700) comprises acquiring (706) a photograph image and finding (708) a position of the testing device (110) in the photograph image. The 5method further comprises acquiring (706) a luminescence image and determining (734-736) a representation of sites of the testing device (110), each comprising at least one luminescence substance, in the luminescence image according to the position of the testing device (110) in the photograph image. The luminescence imaging apparatus (105) is then tested (754-772) according to the representation of the sites (330) in the 0luminescence image. A corresponding computer program (600) and a computer program product for implementing the method (700) are also proposed. Moreover, a testing device (110) for use in the method (700) is proposed.

Abstract: A solution is proposed for testing a luminescence imaging apparatus (105). A corresponding testing device (110) comprises one or more seats (320) and one or more containers (325), each filled with a liquid comprising at least one luminescence substance and accommodated in a corresponding seat (320); the seats (320) have corresponding windows (330) for imaging the luminescence substance of the containers (325) accommodated therein. The seats (320) are slanted with respect to a resting surface (310) of the testing device (110). A holder (305) for use in the testing device (100) is further provided. A luminescence imaging apparatus (105) for use with the testing device (110) is also proposed. Moreover, a system (100) comprising a luminescence imaging apparatus (105) and this testing device (110) is proposed.

Abstract: A hybrid NIRF/IVUS imaging probe containing i) a spatially-truncated optical lens a substantially-planar surface of which is inclined with respect to an axis to reflect light, transmitted between proximal and distal ends of the probe, internally into a body of the lens, and ii) an acoustic transducer disposed sequentially with the optical lens on the axis of the probe while, at the same time, the optical and electrical members of the probe transmitting the radiative and mechanical energies (which the probe exchanges with a target bodily vessel) are parallel to one another within the housing of the probe. A method for operating the probe resulting in formation of spatially co-registered optical and acoustic images of the target. Related imaging system and computer-program product.