Abstract: Systems and methods for applying an ensemble of segmentations to microscopy images of a tissue sample to determine if the tissue sample is representative of cancerous tissue. The ensemble of segmentations is applied to a plurality of greyscale or color microscopy images to generate a final image level segmentation and a final blob level segmentation. The final image level segmentation and final blob level segmentation are used to calculate a mean nuclear volume to determine if the tissue sample is representative of cancerous tissue.

Abstract: A system for generating symmetric cryptographic keys for communications between hosts. Hosts use associated devices to generate secret keys. Each key is generated based on a static seed and a dynamic seed. The dynamic seed is created from sensor data or auxiliary data. The secret key allows host machines to encrypt, or decrypt, plaintext messages sent to, or received from, other host machines.

Abstract: A system for generating symmetric cryptographic keys for communications between hosts. Hosts use associated devices to generate secret keys. Each key is generated based on a static seed and a dynamic seed. The dynamic seed is created from sensor data or auxiliary data. The secret key allows host machines to encrypt, or decrypt, plaintext messages sent to, or received from, other host machines.

Abstract: This invention relates to a system and method for applying an ensemble of segmentations to microscopy images of a tissue sample to determine if the tissue sample is representative of cancerous tissue. The ensemble of segmentations is applied to a plurality of greyscale or color microscopy images to generate a final image level segmentation and a final blob level segmentation. The final image level segmentation and final blob level segmentation are used to calculate a mean nuclear volume to determine if the tissue sample is representative of cancerous tissue.

Abstract: A system and method of authentication is described. In operation, an authenticator computing device receives a request to access a resource from a requesting user. In response to the request, the authenticator computing device generates and transmits an authentication vote query to one or more voting users, wherein the one or more voting users includes at least one user other than the user requesting access to the resources. The one or more voting users then respond by transmitting authentication votes to the authenticator. Alternatively, a proxy may be used to cast the authentication votes of the one or more voting users. The authenticator computing device then analyzes the authentication votes to determine whether the requesting user requesting access to the resource should be granted access and grants the requesting user access to the resource based upon the analysis of the authentication votes.

Abstract: A system and method for applying an ensemble of segmentations to a tissue sample at a blob level and at an image level to determine if the tissue sample is representative of cancerous tissue. The ensemble of segmentations at the image level is used to accept or reject images based upon the segmentation quality of the images and both the blob level segmentation and the image level segmentation are used to calculate a mean nuclear volume to discriminate between cancer and normal classes of tissue samples.

Abstract: A system and method of authentication using an authenticator computing device and at least two registered user devices is described. In operation, the authenticator computing device receives a request to access a resource from one of a plurality of user devices registered to a user. The authenticator computing device generates an authentication challenge in response to the request and the authentication challenge is then transmitted to a subset of the plurality of user devices. One or more of the user devices then subsequently generates and transmits a response to the authentication challenge to the authenticator computing device. The authenticator computing device then determines whether the responses received from the one or more user devices in the subset constitutes a valid response and then grants one or more of the user devices access to the resource if the responses received from the user devices constitutes a valid response to the authentication challenge.

Abstract: A system and method of anonymous authentication is described. In operation, the authenticator receives a request to access a resource from one of the user devices of an associated set of user devices, wherein each of the user devices is registered to at least one user requesting access to the resource registered to at least two users. The authenticator generates and transmits an authentication challenge in response to the request to a subset of the user devices. A user device subsequently generates and transmits a response to the authentication challenge to the authenticator. The authenticator determines whether the responses received from the one or more user devices constitutes a valid response and grants any one or more of the user devices of the associated set of user devices access to the resource if the responses received from the user devices constitutes a valid response to the authentication challenge.

Abstract: A system and method of authentication using an authenticator computing device and at least two registered user devices is described. In operation, the authenticator computing device receives a request to access a resource from one of a plurality of user devices registered to a user. The authenticator computing device generates an authentication challenge in response to the request and the authentication challenge is then transmitted to a subset of the plurality of user devices. One or more of the user devices then subsequently generates and transmits a response to the authentication challenge to the authenticator computing device. The authenticator computing device then determines whether the responses received from the one or more user devices in the subset constitutes a valid response and then grants one or more of the user devices access to the resource if the responses received from the user devices constitutes a valid response to the authentication challenge.

Abstract: A system and method of anonymous authentication is described. In operation, the authenticator receives a request to access a resource from one of the user devices of an associated set of user devices, wherein each of the user devices is registered to at least one user requesting access to the resource registered to at least two users. The authenticator generates and transmits an authentication challenge in response to the request to a subset of the user devices. A user device subsequently generates and transmits a response to the authentication challenge to the authenticator. The authenticator determines whether the responses received from the one or more user devices constitutes a valid response and grants any one or more of the user devices of the associated set of user devices access to the resource if the responses received from the user devices constitutes a valid response to the authentication challenge.

Abstract: Systems and methods are provided for automatic determination of slice thickness of an image stack in a computerized stereology system, as well as automatic quantification of biological objects of interest within an identified slice of the image stack. Top and bottom boundaries of a slice can be identified by applying a thresholded focus function to determine just-out-of-focus focal planes. Objects within an identified slice can be quantified by performing a color processing segmentation followed by a gray-level processing segmentation. The two segmentation processes generate unique identifiers for features in an image that can then be used to produce a count of the features.

Abstract: Systems and methods are provided for automatic determination of slice thickness of an image stack in a computerized stereology system, as well as automatic quantification of biological objects of interest within an identified slice of the image stack. Top and bottom boundaries of a slice can be identified by applying a thresholded focus function to determine just-out-of-focus focal planes. Objects within an identified slice can be quantified by performing a color processing segmentation followed by a gray-level processing segmentation. The two segmentation processes generate unique identifiers for features in an image that can then be used to produce a count of the features.