Abstract: A sensing device that includes (a) an image sensor matrix that comprises a first pixel and a second pixel; wherein the first pixel is configured to generate a first detection signal indicative of a presence of a first analyte; wherein the second pixel is configured to generate a second detection signal that is indifferent to the presence of the first analyte; and (b) a processing circuit that is configured to determine the presence of the first analyte based on at least a relationship between the first detection signal and the second detection signal.

Abstract: Copy Number Variants (CNV) detection methods may integrate CNV detection into workflow for next generation sequencer (NGS) data processing, in parallel with SNP and INDEL variant calling. CNV detection methods may analyze coverage patterns across a set of genomic regions and across samples from different patients. The methods do not require specifically chosen reference samples as, but automatically select reference samples from the same batch, for each sample tested. CNV detection methods may detect CNVs in a set of samples without assumptions about CNV status of any of those samples. Embodiments herein may apply the CNV detection scheme iteratively to improve detection performance. The proposed methods may further comprise the step of iteratively feeding back information about the CNVs in the samples into the next iteration step. The methods may also use information from the NGS workflow, such as information on SNP fractions, as input to the NGS CNV detection.

Abstract: Copy Number Variants (CNV) detection methods described herein may efficiently integrate CNV detection into the workflow for a next generation sequencer (NGS) data processing, in parallel with SNP and INDEL variant calling. CNV detection methods as described herein may be performed by analyzing the coverage pattern across a suitable set of genomic regions or amplicons and across a batch of samples from different patients. The proposed methods do not require the use of specifically chosen reference samples as inputs to the workflow, but rather automatically select a set of reference samples from the same batch, for each sample being tested. The CNV detection methods may reliably detect CNVs in a set of samples without prior assumptions about the CNV status of any of those samples. Embodiments described herein may also apply the CNV detection scheme iteratively to further improve the detection performance, especially in the case of more frequent CNV occurrence.

Abstract: Copy Number Variants (CNV) detection methods described herein may efficiently integrate CNV detection into the workflow for a next generation sequencer (NGS) data processing, in parallel with SNP and INDEL variant calling. CNV detection methods as described herein may be performed by analyzing the coverage pattern across a suitable set of genomic regions or amplicons and across a batch of samples from different patients. The proposed methods do not require the use of specifically chosen reference samples as inputs to the workflow, but rather automatically select a set of reference samples from the same batch, for each sample being tested. The CNV detection methods may reliably detect CNVs in a set of samples without prior assumptions about the CNV status of any of those samples. Embodiments described herein may also apply the CNV detection scheme iteratively to further improve the detection performance, especially in the case of more frequent CNV occurrence.

Abstract: The invention provides devices and methods for depositing uniform coatings using cylindrical magnetron sputtering. The devices and methods of the invention are useful in depositing coatings on non-cylindrical workpiece surfaces. An assembly of electromagnets located within the bore of a hollow cylindrical emitter is used to form a magnetic field exterior to and near the exterior surface of the emitter. The magnet assembly configuration is selected to provide a magnetic field configuration compatible with the workpiece surface contour. The electromagnet assembly may be a plurality of magnet units, each unit having at least one electromagnet. The magnetic field strength from each magnet unit is separately and electrically adjustable. Each electromagnet in the assembly has a coil of electrically conducting material surrounding a specially shaped core of magnetic material.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, are described for: allocating a plurality of nodes; implementing a first pool of workers on the plurality of nodes, each node including one or more of the workers from the first pool; providing a set of instructions to the first pool of workers for performing a first task configured to interact with the computer system; employing the first pool of workers to perform the first task; and monitoring at least one performance metric associated with the computer system while the workers from the first pool are performing the first task.

Abstract: Methods and apparatus are presented for determining position a GNSS rover antenna from single-frequency observations of GNSS signals collected at the antenna over multiple epochs and from correction data for at least one of the epochs. Coded raw data prepared from the single-frequency observations in a binary format are obtained and decoded to obtain decoded raw data. The decoded raw data are used to construct multiple epochs of measurement data of time, range and phase. Correction data are obtained for at least one of the epochs. The measurement data are processed with the correction data in a realtime kinematic positioning engine to obtain a position estimate for each of a plurality of epochs.

Abstract: The invention provides devices and methods for depositing uniform coatings using cylindrical magnetron sputtering. The devices and methods of the invention are useful in depositing coatings on non-cylindrical workpiece surfaces. An assembly of electromagnets located within the bore of a hollow cylindrical emitter is used to form a magnetic field exterior to and near the exterior surface of the emitter. The magnet assembly configuration is selected to provide a magnetic field configuration compatible with the workpiece surface contour. The electromagnet assembly may be a plurality of magnet units, each unit having at least one electromagnet. The magnetic field strength from each magnet unit is separately and electrically adjustable. Each electromagnet in the assembly has a coil of electrically conducting material surrounding a specially shaped core of magnetic material.

Abstract: The invention provides devices and methods for depositing uniform coatings using cylindrical magnetron sputtering. The devices and methods of the invention are useful in depositing coatings on non-cylindrical workpiece surfaces. An assembly of electromagnets located within the bore of a hollow cylindrical emitter is used to form a magnetic field exterior to and near the exterior surface of the emitter. The magnet assembly configuration is selected to provide a magnetic field configuration compatible with the workpiece surface contour. The electromagnet assembly may be a plurality of magnet units, each unit having at least one electromagnet. The magnetic field strength from each magnet unit is separately and electrically adjustable. Each electromagnet in the assembly has a coil of electrically conducting material surrounding a specially shaped core of magnetic material.

Abstract: Methods and apparatus are presented for determining position a GNSS rover antenna from single-frequency observations of GNSS signals collected at the antenna over multiple epochs and from correction data for at least one of the epochs. Coded raw data prepared from the single-frequency observations in a binary format are obtained and decoded to obtain decoded raw data. The decoded raw data are used to construct multiple epochs of measurement data of time, range and phase. Correction data are obtained for at least one of the epochs. The measurement data are processed with the correction data in a realtime kinematic positioning engine to obtain a position estimate for each of a plurality of epochs.

Abstract: The invention provides devices and methods for depositing uniform coatings using cylindrical magnetron sputtering. The devices and methods of the invention are useful in depositing coatings on non-cylindrical workpiece surfaces. An assembly of electromagnets located within the bore of a hollow cylindrical emitter is used to form a magnetic field exterior to and near the exterior surface of the emitter. The magnet assembly configuration is selected to provide a magnetic field configuration compatible with the workpiece surface contour. The electromagnet assembly may be a plurality of magnet units, each unit having at least one electromagnet. The magnetic field strength from each magnet unit is separately and electrically adjustable. Each electromagnet in the assembly has a coil of electrically conducting material surrounding a specially shaped core of magnetic material.

Abstract: The invention provides devices and methods for depositing uniform coatings using cylindrical magnetron sputtering. The devices and methods of the invention are useful in depositing coatings on non-cylindrical workpiece surfaces. An assembly of electromagnets located within the bore of a hollow cylindrical emitter is used to form a magnetic field exterior to and near the exterior surface of the emitter. The magnet assembly configuration is selected to provide a magnetic field configuration compatible with the workpiece surface contour. The electromagnet assembly may be a plurality of magnet units, each unit having at least one electromagnet. The magnetic field strength from each magnet unit is separately and electrically adjustable. Each electromagnet in the assembly has a coil of electrically conducting material surrounding a specially shaped core of magnetic material.

Abstract: The invention relates to a method for producing monocyclic ketones C7-C20. The method of patent protection sought is based on the oxidation reaction of monocyclic alkenes C7-C20 into corresponding monocyclic ketones with nitrous oxide or a mixture thereof with inert gas. The process proceeds at a temperature ranging from 20 to 350° C. and a pressure of the nitrous oxide ranging from 0.01 to 100 atm. The process provides a high selectivity involving the target product, blast-resistant work operations and is promising for industrial use.

Abstract: Millions of schoolchildren take a ride to and from school on buses every day. Quite frequently we hear about multiple problems with the school buses. The school bus did not arrive on time, the bus did not show up at all, or the time or place of a bus stop has changed without notification—all these problems are unfortunately very common. Today's School Transportation systems do not always work as fast and as reliably as it is reasonably expected. These systems use phone or fax-based communication. These methods are slow, inefficient, and can be catastrophic since children's safety is on the line. Online Schoolchildren Transportation Management Method, System, and Computer Program Products, store data and provide real-time communication between the main participants of the schoolchildren transportation process: school transportation officers, district, county and/or state transportation management, schoolchildren and/or parents, and/or school bus drivers via a Web based network.