Patents by Inventor Do-Bu Lee

Do-Bu Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10364459
    Abstract: A method of quantitatively and qualitatively analyzing a biomaterial in real-time, the method comprising preparing a device for detecting a biomaterial, feeding a complex of first and second probes, a forward primer, a reverse primer, a sample comprising deoxynucleotide triphosphate, a polymerase having exonuclease activity, and a sample comprising target genes, and a reaction solution comprising a buffer into the reaction container, performing polymerase chain reaction comprising denaturation of the target genes in the sample, hybridization of the target genes, the complex, and the forward and reverse primers in the sample, and elongation of the primers through the polymerase having exonuclease activity, allowing for elongation of the second probe on the third probe by the polymerase after hybridizing the released second probe and the third probe fixed to the biochip, detecting a first fluorescence signal by the first phosphor and a second fluorescence signal by the second phosphor.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: July 30, 2019
    Assignee: SUGENTECH, Inc.
    Inventors: Lee-Kyung Kim, Mun-Cheol Paek, Su-Jin Ku, Sun-Young Park, Do-Bu Lee, Jae-Hyung Park, Ki-Chang Lee, Nam-Joong Kim
  • Patent number: 9551038
    Abstract: Provided are a system for integrated analysis of a real-time polymerase chain reaction and a DNA chip and a method for integrated analysis using the same, and more particularly to an apparatus for integrated analysis of a real-time polymerase chain reaction and a DNA chip and a method for integrated analysis using the same. According to the method for integrated analysis of a biomaterial of the present invention, gene amplification proceeds and subsequently hybridization proceeds in a single reactor, thereby preventing contamination of the sample due to external factors, which may be caused while the sample is transferred for reaction, and automating a series of procedures such as injection of the sample, reaction of the biomaterial, and detection and analysis of results.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: January 24, 2017
    Assignee: K-MAC
    Inventors: Sung-Min Seo, Do-Bu Lee, Joong Hwan Lee, Mun-Cheol Paek, Su-Jin Ku
  • Publication number: 20160186236
    Abstract: A method of quantitatively and qualitatively analyzing a biomaterial in real-time, the method comprising preparing a device for detecting a biomaterial, feeding a complex of first and second probes, a forward primer, a reverse primer, a sample comprising deoxynucleotide triphosphate, a polymerase having exonuclease activity, and a sample comprising target genes, and a reaction solution comprising a buffer into the reaction container, performing polymerase chain reaction comprising denaturation of the target genes in the sample, hybridization of the target genes, the complex, and the forward and reverse primers in the sample, and elongation of the primers through the polymerase having exonuclease activity, allowing for elongation of the second probe on the third probe by the polymerase after hybridizing the released second probe and the third probe fixed to the biochip, detecting a first fluorescence signal by the first phosphor and a second fluorescence signal by the second phosphor.
    Type: Application
    Filed: May 30, 2014
    Publication date: June 30, 2016
    Inventors: Lee-Kyung KIM, Mun-Cheol PAEK, Su-Jin KU, Sun-Young PARK, Do-Bu LEE, Jae-Hyung PARK, Ki-Chang LEE, Nam-Joong KIM
  • Publication number: 20130303390
    Abstract: Provided are a system for integrated analysis of a real-time polymerase chain reaction and a DNA chip and a method for integrated analysis using the same, and more particularly to an apparatus for integrated analysis of a real-time polymerase chain reaction and a DNA chip and a method for integrated analysis using the same. According to the method for integrated analysis of a biomaterial of the present invention, gene amplification proceeds and subsequently hybridization proceeds in a single reactor, thereby preventing contamination of the sample due to external factors, which may be caused while the sample is transferred for reaction, and automating a series of procedures such as injection of the sample, reaction of the biomaterial, and detection and analysis of results.
    Type: Application
    Filed: July 20, 2012
    Publication date: November 14, 2013
    Inventors: Sung-Min Seo, Do-Bu Lee, Joong Hwan Lee, Mun-Cheol Paek, Su-Jin Ku