Abstract: The present invention relates to a method for predicting reactivity to anticancer drugs by analyzing genomic DNA methylation status and, more specifically to a method for predicting reactivity to anticancer drugs by analyzing the methylation status of adjacent CpG sites in genomic DNA. The method of the present invention can accurately predict reactivity to anticancer drugs by using the methylation disorderness of CpG sites in genomic DNA, and thus can be very useful in the selection of drugs for cancer patient treatment.

Abstract: Disclosed is a rotating discharge type cosmetic container including: an outer case formed therein with a first fixed connection portion; a rotation operating member rotatably coupled to an inside of the outer case and formed therein with a first rotation connecting portion; an inner case detachably coupled to the rotation operating member to accommodate cosmetic contents therein; a rotating member rotatably coupled to the inner case, formed therein with a second rotation connecting portion, and having one surface formed with a discharge port; an operating member connected to the rotation operating member and rotated together with the rotation operating member; a lifting member screw-coupled with the operating member, moved in a straight line within the inner case, and formed therein with a second fixed connection portion; and a piston for moving the cosmetic contents while being moved up and down together with the lifting member.

Abstract: A liquid contents ejection container having a nozzle blocking structure, according to an embodiment of the present invention, comprises: a container body in which liquid contents are stored; an ejection means connected to the container body so as to eject the liquid contents; a push button which is connected to the ejection means so as to operate the ejection means, and which has an ejection path formed therein; and a nozzle blocking means composed of a nozzle, which is coupled to one side of the push button and has an ejection hole, an elastic body, which is formed in the nozzle and is elastically deformed, and a nozzle valve, which opens/closes the ejection hole while moving back and forth by means of the elastic body, wherein the nozzle valve is spaced from the ejection hole so as to open the ejection hole while the elastic body is stretched outward from the inside of the nozzle, and the nozzle valve covers the ejection hole on the outer side thereof so as to close the ejection hole while the elastic body

Abstract: Disclosed is a method of controlling a display device displaying an image using a lens, the method including storing a lens distortion parameter for chromatic aberration correction, receiving image data, primarily calculating a distance between a center point and a current pixel, secondarily calculating a distortion correction weight in consideration of the distance, and outputting image data of the current pixel through calculation according to the calculated distortion correction weight without using the stored lens distortion parameter intactly.

Abstract: The present disclosure relates to a technique for selectively reproducing multiple sounds for respective areas of a display through image analysis for each display area. A technique, for individually controlling multiple audio devices by analyzing an image to extract regions of the image and classifying sound types through data learning, can be provided.

Abstract: A display driving method includes receiving an image; calculating a distance between a current point and a current pixel for a sub-pixel of the image; calculating a weight based on a parameter; and compensating for distortion in the image based on the weight. A color of the sub-pixel may include at least one of red, green, or blue, and the parameter may include at least one of a distance parameter, a distortion parameter, or a sub-pixel parameter.

Abstract: A tube-type liquid discharging container according to an embodiment of the present invention comprises: a tube body having contents stored therein and having an inlet part; a shoulder coupled to the inlet part of the tube body and having a discharge port; an inner housing formed inside the shoulder and having a contents inlet hole formed on one side thereof; an opening and closing rod formed on the inner housing to open and close the discharge port by reciprocating; an elastic member elastically supporting the opening and closing rod; an outer housing coupled to the inner housing by surrounding the outer side of the inner housing, and having a contents outlet; and a valve installed on the contents outlet of the outer housing to open and close the contents outlet, wherein the inner housing and the outer housing are located a fixed distance away from each other, and a flow channel for contents is formed therebetween.

Abstract: Disclosed is a rotating discharge type cosmetic container including: an outer case formed therein with a first fixed connection portion; a rotation operating member rotatably coupled to an inside of the outer case and formed therein with a first rotation connecting portion; an inner case detachably coupled to the rotation operating member to accommodate cosmetic contents therein; a rotating member rotatably coupled to the inner case, formed therein with a second rotation connecting portion, and having one surface formed with a discharge port; an operating member connected to the rotation operating member and rotated together with the rotation operating member; a lifting member screw-coupled with the operating member, moved in a straight line within the inner case, and formed therein with a second fixed connection portion; and a piston for moving the cosmetic contents while being moved up and down together with the lifting member.

Abstract: A rotational discharge-type cosmetic container according to an embodiment of the present invention comprises: an outer container having a coupling extension portion formed therein; an inner container of which rotation is restricted by being fitted into the coupling extension portion of the outer container and in which content is received; a rotary member rotatably coupled to the outer side of the inner container and having at least one discharge port formed therethrough; a rotary operation member connected to the rotary member to be rotated together and having a first screw thread formed thereon; and a piston screw-coupled to the rotary operation member, fitted into the coupling extension portion of the outer container to be movable in a straight line, formed in the inner container and an elevating member having a second screw thread formed on.

Abstract: Disclosed is a cosmetic case having a refill structure including: a container body having one opened side and formed with an elevation spiral groove; an outer cap rotatably coupled to the container body and formed with an elevation straight groove; an elevation mechanism elevated in the container body while being rotated with the outer cap and formed with an elevation protrusion; a content container accommodated inside the container body to store contents; a discharging mechanism installed in the content container to discharge the contents; an inner cap coupled to one side of the content container and elevated with the elevation mechanism; and an operation button connected to the discharging mechanism to discharge the contents, wherein the elevation mechanism and the inner cap are formed with a fastening protrusion and a fastening groove and formed with a refill guide groove and a refill guide protrusion, respectively.

Abstract: A display driving apparatus includes a display panel comprising a first display area displaying a first image and a second display area being maintained in a turn-off state during a hybrid mode; a source driving circuit configured to supply a first source signal to first pixels included in the first display area and supply a second source signal to second pixels included in the second display area to sense electrical characteristics of the second pixels when the display panel operates in the hybrid mode; and a timing controller configured to transfer first image data for the first image and sensing data for sensing to the source driving circuit and compensate for second image data for a second image which is to be displayed after displaying of the first image, based on a target compensation value obtained from the electrical characteristics sensed by the source driving circuit, wherein the target compensation value is determined based on a third image displayed in a previous display mode of the hybrid mode.

Abstract: A container for discharging liquid contents according to an embodiment of the present invention comprises: an inner container in which liquid contents are accommodated; an outer container surrounding the outside of the inner container; a sealing frame which blocks an open side of the outer container, is coupled with the inner container, and has an air inlet hole; an air inlet valve which is installed in the sealing frame and opens and closes the air inlet hole in response to changes in the pressure inside the outer container; a shoulder which is coupled to one side of the outer container and surrounds the sealing frame, and has a discharge passage formed therein; a nozzle which is coupled to the shoulder and has a discharge port formed therein; and a discharge valve which is installed on the shoulder and opens and closes the discharge passage by means of the discharge pressure of the liquid contents.

Abstract: An embodiment enables natural and smooth change in the brightness of a backlight unit and is able to reduce flicker by changing a dimming value between frames through a mixed function including a plurality of functions having different characteristics.

Abstract: A compact container having a refill container replacement structure according to an embodiment of the present invention comprises: a container body having a moving-up/down diagonal groove formed therein; a container lid opening/closing the container body; a container lid opening and closing the container body; an intermediate body which is coupled to the inside of the container body to be rotatable within a certain section and has a moving-up/down vertical hole formed therein; a refill container holder which is coupled into the intermediate body and has a moving-up/down protrusion that is inserted in the moving-up/down diagonal groove through the moving-up/down vertical hole; and a refill container coupled to the refill container holder and accommodating content therein.

Abstract: A display driving apparatus includes a source driving circuit supplying a first source signal to a first display area to display a first image and supply a second source signal to a second display area to sense characteristics of a pixels of the second display area when a display panel operates in a hybrid mode, the second display area being in a turn-off state during the hybrid mode, a gate driving circuit supplying a gate pulse to first gate lines of the first display area and supply the gate pulse to target gate lines of the second display area, a timing controller transferring first image data for the first image and sensing data for sensing to the source driving circuit and compensate for second image data for a second image which is to be displayed after the first image, based on a target compensation value obtained from a sensing result.

Abstract: The present disclosure relates to a composition for preventing or treating fibrosis including an inhibitor of cyclin-dependent kinase 17 (CDK17) expression or activity. According to the present disclosure, the inhibitor of CDK17 expression or activity significantly reduces collagen production and cell activity and viability in activated hepatic stellate cells (liver fibrosis cell model), renal tubular epithelial cells (renal fibrosis cell model) in which fibrosis is induced by TGF-? treatment, and alveolar epithelial cells (lung fibrosis cell model) in which fibrosis is induced by TGF-? treatment, indicating that the composition of the present disclosure has an excellent effect in preventing or treating fibrosis.

Abstract: disclosed is a stick container having a sealing structure for preventing a residue, which includes: a main body formed thereon with an elevation protrusion; a sealing tube coupled into the main body and formed with first and second sealing parts; a guide tube rotatably coupled into the main body and formed with an inlet part; a first holder coupled into the guide tube; a second holder coupled into the first holder and formed with an elevation thread; and a main body cover opening and closing the guide tube and formed with a sealing cap, wherein the first sealing part comes into close contact with the main body to seal a space between the main body and the sealing tube, and the second sealing part simultaneously comes into close contact with the guide tube to seal a space between the sealing tube and the guide tube.