Patents by Inventor Domingo Sanchez
Domingo Sanchez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6994791Abstract: The present invention relates to an adsorbent material for chromatography comprising a polymer immobilized onto a support, wherein the polymer backbone is attached to the support by one or more linkages which comprise one or more amide groups. It further relates to a method for preparing an adsorbent material for chromatography wherein a support is reacted with a polymer.Type: GrantFiled: June 27, 2003Date of Patent: February 7, 2006Assignee: Akzo Nobel N.V.Inventors: Per Möller, Domingo Sanchez, Peter Gidlund, Börje S. Persson, Lars Jonsson
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Publication number: 20040157209Abstract: The present invention relates to molecularly imprinted polymers comprising tailor-made recognition sites for a target in which said recognition sites are located at or close to the surface of the polymer and/or of pores in the polymer. The molecularly imprinted polymer comprising tailor-made recognition sites for a target is obtainable by polymerising functional monomers and, optionally, cross-linked, optionally in a reaction solvent, in the presence of at least one template immobilised on a support material in a polymerisation process, whereby non-covalent or covalent are formed between said functional monomers and said immobilised template(s), and removing said template(s), and said support material from the molecularly imprinted polymer.Type: ApplicationFiled: October 27, 2003Publication date: August 12, 2004Inventors: Ecevit Yilmaz, Karsten Haupt, Klaus Mosbach, Domingo Sanchez, Per Moller
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Publication number: 20040059040Abstract: The present invention relates to an adsorbent material for chromatography comprising a polymer immobilised onto a support, wherein the polymer backbone is attached to the support by one or more linkages which comprise one or more amide groups. It further relates to a method for preparing an adsorbent material for chromatography wherein a support is reacted with a polymer.Type: ApplicationFiled: June 27, 2003Publication date: March 25, 2004Inventors: Per Moller, Domingo Sanchez, Peter Gidlund, Borje S. Persson, Lars Jonsson
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Patent number: 6333426Abstract: Opticallly active adsorbents based on network polymerized derivative of dicarboxylic acids, diamines or diols which are chemically bonded to a carrier. The derivatives can be polymerized by radical polymerization or through hydrosilylation in the presence of a solid carrier. The optically active adsorbents are usable for chromatographic separation of racemic mixtures of enantiomers.Type: GrantFiled: September 28, 1999Date of Patent: December 25, 2001Assignee: EKA Nobel ABInventors: Per Moller, Domingo Sanchez, Stig Allenmark, Shalini Andersson
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Patent number: 6277782Abstract: Optically active adsorbents based on network polymerized derivatives of dicarboxylic acids, diamines or diols which are chemically bonded to a carrier. The derivatives can be polymerized by radical polymerization or through hydrosilylation in the presence of a solid carrier. The optically active adsorbents are usable for chromatographic separation of racemic mixtures of enantiomers.Type: GrantFiled: June 26, 1995Date of Patent: August 21, 2001Assignee: Eka Nobel ABInventors: Per Moller, Domingo Sanchez, Stig Allenmark, Shalini Andersson
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Patent number: 5286747Abstract: Compounds of the formula ##STR1## wherein R.sup.3 and the NR.sup.1 R.sup.2 group are in a cis-position to each other and wherein Y is OH, R.sup.4 COO, (R.sup.5).sub.2 NCOO or R.sup.6 O either in position 5 or position 7, whereby R.sup.4 is an alkyl group having 1-5 carbon atoms or a possibly substituted phenyl group, R.sup.5 is an alkyl group having 1-5 carbon atoms and R.sup.6 is an allyl or benzyl group, R.sup.1 is hydrogen or an alkyl group having 1-3 carbon atoms, R.sup.2 is an alkyl group having 1-6 carbon atoms, a phenylalkyl- or m-hydroxyphenylalkyl group with 2-4 carbon atoms in the alkyl part, or an alkenyl group with 3-6 carbon atoms other than 1-alkenyl, and R.sup.3 is an alkyl group having 1-3 carbon atoms, processes and intermediates for their preparation, pharmaceutical preparations and methods of treatment employing such compounds. The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system.Type: GrantFiled: September 29, 1989Date of Patent: February 15, 1994Assignee: Per A. E. CarlssonInventors: Folke L. Arvidsson, Per A. E. Carlsson, Uli A. Hacksell, John S. M. Hjorth, Anette M. Johansson, Per L. Lindberg, John L. G. Nilsson, Domingo Sanchez, H.ang.kan V. Wikstrom
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Patent number: 5128120Abstract: New 9-anthrylalkyl compounds having the general formula ##STR1## wherein R is hydrogen or an alkyl group, whereby, however, not more than one of the groups R is an alkyl group; R.sub.1 is hydrogen, lower alkyl, halogen or nitro; n is an integer of from 1 to 7, whereby, however, the total number of carbon atoms in the group --CHR--(CHR).sub.n -- does not exceed 8; and X is halogen, an azide group or a succinimidyl group.The new compounds are prepared from 9-anthrylalcohols which are reacted with a compound X--CO--X wherein X is a halogen, and then optionally with compounds giving azide or succinimidyl group. The compounds are used as derivatization reagents for separation and detection purposes.Intermediates for preparation of the above defined 9-anthrylalkyl compounds wherein one R is an alkyl group are 9-anthrylalcohols with the group --CHR--(CHR).sub.n --OH, wherein one R is an alkyl group.Type: GrantFiled: February 5, 1991Date of Patent: July 7, 1992Assignee: Eka Nobel ABInventors: Hans-Dieter Becker, Stefan Einarsson, Andrzej Grzegorczyk, Bjorn Josefsson, Stig S. Lagerkvist, Per L. Moller, Domingo Sanchez, Johan H. Sorensen
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Patent number: 5015755Abstract: New 9-anthrylalkyl compounds having the general formula ##STR1## wherein R is hydrogen or an alkyl group, whereby, however, not more than one of the groups R is an alkyl group; R.sub.1 is hydrogen, lower alkyl, halogen or nitro; n is an integer of from 1 to 7, whereby, however, the total number of carbon atoms in the group --CHR--(CHR).sub.n -- does not exceed 8; and X is halogen, an azide group or a succinimidyl group.The new compounds are prepared from 9-anthrylalcohols which are reacted with a compound X--CO--X wherein X is a halogen, and then optionally with compounds giving azide or succinimidyl group. The compounds are used as derivatization reagents for separation and detection purposes.Intermediates for preparation of the above defined 9-anthrylalkyl compounds wherein one R is an alkyl group are 9-anthrylalcohols with the group --CHR--(CHR).sub.n --OH, wherein one R is an alkyl group.Type: GrantFiled: August 10, 1989Date of Patent: May 14, 1991Assignee: Eka Nobel ABInventors: Hans-Dieter Becker, Stefan Einarsson, Andrzej Grzegorczyk, Bjorn Josefsson, Stig S. Lagerkvist, Per L. Moller, Domingo Sanchez, Johan H. Sorensen
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Patent number: 4937346Abstract: Compound of the formula ##STR1## wherein n is 1 or 2, Y is OH, R.sup.1 COO--, R.sup.2 R.sup.3 NCOO-- or R.sup.4 O whereby R.sup.1 is an alkyl group, or a possibly substituted phenyl group, R.sup.2 is an alkyl, phenethyl, or benzyl or phenyl group, R.sup.3 is H or an alkyl group and R.sup.4 is an allyl or benzyl group, and R is an alkyl, hydroxyalkyl, dimethylaminoalkyl or methylthioalkyl group or alkenyl group, processes for their preparations and methods of treatment employing such compounds. The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system.Type: GrantFiled: November 30, 1987Date of Patent: June 26, 1990Assignee: Per Arvid Emil CarlssonInventors: Folke L. Arvidsson, Per A. E. Carlsson, Uli A. Hacksell, John S. M. Hjorth, Per L. Lindberg, John L. G. Nilsson, Domingo Sanchez, Nils U. E. Svensson, Hakan V. Wikstrom
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Patent number: 4818704Abstract: The invention relates to a new chiral reagent of the formula ##STR1## wherein X is halogen, an azide group or a succinimidyl group and wherein R is an alkyl group or a trifluormethyl group. The invention further relates to a method for the derivatization, determination and preparation resolution of primary and secondary amino-containing compounds. The method comprises the steps of derivatizing the amino function by the reagent to form diastereomeric carbamates, which are determined by e.g. fluorimetry or absorptiometry after separation by liquid chromatography.Type: GrantFiled: January 25, 1988Date of Patent: April 4, 1989Assignee: Eka Nobel ABInventors: Bjorn Josefsson, Stefan Einarsson, Domingo Sanchez, Per Moller
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Patent number: 4719219Abstract: Compound of the formula ##STR1## wherein n is 1 or 2, Y is OH, R.sup.1 COO--, R.sup.2 R.sup.3 NCOO-- or R.sup.4 O whereby R.sup.1 is an alkyl group, or a possibly substituted phenyl group, R.sup.2 is an alkyl, phenethyl, or benzyl or phenyl group, R.sup.3 is H or an alkyl group and R.sup.4 is an allyl or benzyl group, and R is an alkyl, hydroxyalkyl, dimethylaminoalkyl or methylthioalkyl group or alkenyl group, processes for their preparations and methods of treatment employing such compounds. The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system.Type: GrantFiled: October 1, 1984Date of Patent: January 12, 1988Assignee: Per A. E. CarlssonInventors: Folke L. E. Arvidsson, Per A. E. Carlsson, Uli A. Hacksell, John S. M. Hjorth, Per L. Lindberg, John L. G. Nilsson, Domingo Sanchez, Nils U. E. Svensson, Hakan V. Wikstrom
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Patent number: 4612316Abstract: Compounds of the formula ##STR1## wherein C.sup.1 and N.sup.4 are in trans configuration to each other, wherein R and Y are defined herein below, as bases and pharmaceutically acceptable acid addition salts thereof, processes for their preparation and pharmaceutical preparations and methods of treatment employing such compounds. The compounds are useful for treatment of disorders in the central nervous system.Type: GrantFiled: April 19, 1984Date of Patent: September 16, 1986Assignee: Astra Lakemedel AktiebolagInventors: Bengt R. Andersson, Folke L. Arvidsson, Per A. E. Carlsson, John S. M. Hjort, Anette M. Johansson, Per L. Lindberg, John L. G. Nilsson, Domingo Sanchez, Kjell A. I. Svensson, Hakan V. Wikstrom
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Patent number: 4426386Abstract: Compounds of the formula ##STR1## wherein n is 1 or 2, Y is OH, R.sup.1 COO--, R.sup.2 R.sup.3 NCOO-- or R.sup.4 O whereby R.sup.1 is an alkyl group, or a possibly substituted phenyl group, R.sup.2 is an alkyl, phenethyl, benzyl or phenyl group, R.sup.3 is H or an alkyl group and R.sup.4 is an allyl or benzyl group, and R is an alkyl, hydroxyalkyl, dimethylaminoalkyl or methylthioalkyl group or alkenyl group, processes for their preparation and pharmaceutical preparations and methods of treatment employing such compounds. The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system.Type: GrantFiled: December 5, 1980Date of Patent: January 17, 1984Assignee: Astra Lakemedel AktiebolagInventors: Folke L. Arvidsson, Per A. E. Carlsson, Uli A. Hacksell, John S. M. Hjorth, Per. L. Lindberg, John L. G. Nilsson, Domingo Sanchez, Nils U. E. Svensson, Hakan V. Wikstrom