Patents by Inventor Domingos Silva

Domingos Silva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AZAINDOLE INHIBITORS OF AURORA KINASES
    Publication number: 20080081808
    Abstract: The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.
    Type: Application
    Filed: September 14, 2007
    Publication date: April 3, 2008
    Inventors: Martha Sarpong, Nicholas Adams, Jeffrey Axten, Amita Chaudhari, Dashyant Dhanak, Toshihiro Hamajima, Kenneth Newlander, Cynthia Parrish, Jerry Adams, Domingos Silva, Jun Tang
  • NOVEL COMPOUNDS
    Publication number: 20080032969
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 16, 2007
    Publication date: February 7, 2008
    Inventors: Jerry Adams, Jefrrey Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos Silva, John Taggart
  • NOVEL COMPOUNDS
    Publication number: 20080033170
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 16, 2007
    Publication date: February 7, 2008
    Inventors: Jerry Adams, Jeffrey Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos Silva, John Taggart
  • Substituted Pyrazolopyrimidines
    Publication number: 20070293489
    Abstract: Pyrazolo-pyrimidine derivatives are described herein. The described invention also includes methods of making such derivatives as well as methods of using the same in the treatment of diseases.
    Type: Application
    Filed: May 11, 2007
    Publication date: December 20, 2007
    Inventors: Jerry Adams, Jiri Kasparec, Domingos Silva, Catherine Yuan
  • Peptide deformylase inhibitors
    Publication number: 20050222412
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Application
    Filed: May 30, 2003
    Publication date: October 6, 2005
    Inventors: Kelly Aubart, Andrew Benowitz, Siegfried Christensen, Joseph Karpinski, Jinhwa Lee, Domingos Silva
  • Novel Compounds
    Publication number: 20050203109
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 19, 2003
    Publication date: September 15, 2005
    Inventors: Jerry Adams, Jeffrey Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos Silva, John Taggart
  • Chemical compounds
    Publication number: 20050004142
    Abstract: Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Application
    Filed: September 10, 2002
    Publication date: January 6, 2005
    Inventors: Jerry Adams, Deborah Bryan, Yanhong Feng, Shinichiro Matsunaga, Yutaka Maeda, Yasushi Miyazaki, Masato Nakano, Jean-Philippe Rocher, Hideyuki Sato, Marcus Semones, Domingos Silva, Jun Tang