Patents by Inventor Dominic Gregor Hoch

Dominic Gregor Hoch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sesquiterpenoid analogs
    Patent number: 11814396
    Abstract: The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: November 14, 2023
    Assignees: Purdue Research Foundation, University of Florida Research Foundation, Inc.
    Inventors: Mingji Dai, Dexter Cameron Davis, Alexander Adibekian, Dominic Gregor Hoch, Zhong-Yin Zhang
  • Sesquiterpenoid analogs
    Patent number: 11518770
    Abstract: The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: December 6, 2022
    Assignees: Purdue Research Foundation, University of Florida Research Foundation, Inc.
    Inventors: Mingji Dai, Dexter Cameron Davis, Alexander Adibekian, Dominic Gregor Hoch, Zhong-Yin Zhang
  • NOVEL SESQUITERPENOID ANALOGS
    Publication number: 20210261565
    Abstract: The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging thugs for cancers.
    Type: Application
    Filed: May 3, 2021
    Publication date: August 26, 2021
    Applicant: Purdue Research Foundation
    Inventors: Mingji Dai, Dexter Cameron Davis, Alexander Adibekian, Dominic Gregor Hoch, Zhong-Yin Zhang
  • NOVEL SESQUITERPENOID ANALOGS
    Publication number: 20200040000
    Abstract: The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.
    Type: Application
    Filed: August 5, 2019
    Publication date: February 6, 2020
    Applicant: Purdue Research Foundation
    Inventors: Mingji Dai, Dexter Cameron Davis, Alexander Adibekian, Dominic Gregor Hoch, Zhong-Yin Zhang