Patents by Inventor Dominic Jian-Chien Heng

Dominic Jian-Chien Heng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nuclear receptor and mutant thereof and the use of the same in the reprogramming of cells
    Patent number: 9963682
    Abstract: According to the invention there is provided methods for inducing pluripotent stem cells in vitro, vectors and compositions for producing the same and methods for using the induced pluripotent stem cell for treating a patient in need of a pluripotent stem cell treatment.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: May 8, 2018
    Assignee: Agency for Science, Technology and Research
    Inventors: Dominic Jian-Chien Heng, Huck Hui Ng
  • NUCLEAR RECEPTOR AND MUTANT THEREOF AND THE USE OF THE SAME IN THE REPROGRAMMING OF CELLS
    Publication number: 20160376559
    Abstract: According to the invention there is provided methods for inducing pluripotent stem cells in vitro, vectors and compositions for producing the same and methods for using the induced pluripotent stem cell for treating a patient in need of a pluripotent stem cell treatment.
    Type: Application
    Filed: June 27, 2016
    Publication date: December 29, 2016
    Applicant: Agency for Science, Technology and Research
    Inventors: Dominic Jian-Chien Heng, Huck Hui Ng
  • Nuclear receptor and mutant thereof and the use of the same in the reprogramming of cells
    Patent number: 9422525
    Abstract: According to the invention there is provided methods for inducing pluripotent stem cells in vitro, comprising introducing a gene or polypeptide of a nuclear receptor and one or more gene or polypeptide selected from the group consisting of Sox, Krüppel-like factor or the myc family, to cells in vitro. The present invention also provides vectors and compositions for producing the same and methods for using the induced pluripotent stem cell for treating a patient in need of a pluripotent stem cell treatment.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: August 23, 2016
    Assignee: Agency for Science, Technology and Research
    Inventors: Dominic Jian-Chien Heng, Huck Hui Ng
  • NUCLEAR RECEPTOR AND MUTANT THEREOF AND THE USE OF THE SAME IN THE REPROGRAMMING OF CELLS
    Publication number: 20120189596
    Abstract: According to the invention there is provided methods for inducing pluripotent stem cells in vitro, comprising introducing a gene or polypeptide of a nuclear receptor and one or more gene or polypeptide selected from the group consisting of Sox, Krüppel-like factor or the myc family, to cells in vitro. The present invention also provides vectors and compositions for producing the same and methods for using the induced pluripotent stem cell for treating a patient in need of a pluripotent stem cell treatment.
    Type: Application
    Filed: September 30, 2010
    Publication date: July 26, 2012
    Applicant: Agency for Science, Technology and Research
    Inventors: Dominic Jian-Chien Heng, Huck Hui Ng