Patents by Inventor Dominic King-Smith
Dominic King-Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230414551Abstract: The present disclosure relates generally to compositions of nitroglycerin and related organic nitrates, and methods for treating conditions such as Raynaud's phenomenon in which peripheral blood flow in a subject is compromised.Type: ApplicationFiled: June 27, 2023Publication date: December 28, 2023Inventors: Edward T. Kisak, John M. Newsam, R. Dominic King-Smith
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Patent number: 11642356Abstract: In one example presented herein, is a pharmaceutical composition. The pharmaceutical composition can include halobetasol propionate, from 0 wt % to 3 wt % ethoxylated castor oil, a first compound, and a second compound. The first compound and the second compound can be selected from; N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate, and sodium lauryl sulfoacetate. The first compound and the second compound are not the same.Type: GrantFiled: October 21, 2016Date of Patent: May 9, 2023Assignee: Crescita Therapeutics Inc.Inventors: Wade Hull, Ngoc Truc-Chi Vo, Dominic King-Smith
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Publication number: 20200352886Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: ApplicationFiled: February 12, 2020Publication date: November 12, 2020Inventors: Jagat SINGH, Joseph Zev SHAINHOUSE, Bradley S. GALER, Robert Dominic KING-SMITH, Lisa Marie GRIERSON, Maria BURIAN, Jonathan WILKIN, Edward T. KISAK, John M. NEWSAM
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Patent number: 10646441Abstract: The present invention provides DMSO-containing foamable formulations, methods for preparation, and methods of treatment. The formulations can provide good permeability and bioavailability at the target site. Preferably, the formulations are useful for treating osteoarthritis. In one embodiment, the invention provides a foamable formulation for topical use, said formulation comprising DMSO, polyalkylene glycol alkyl ether, an active agent, a monohydric lower alcohol, a diol, and water. Preferably, the active agent is a non-steroidal anti-inflammatory drug, such as diclofenac sodium or ibuprofen.Type: GrantFiled: November 30, 2017Date of Patent: May 12, 2020Assignee: NUVO PHARMACEUTICALS INC.Inventors: Servet Buyuktimkin, Nadir Buyuktimkin, Edward Kisak, Jagat Singh, John M. Newsam, Dominic King-Smith, Bradley S. Galer
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Publication number: 20190269636Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: ApplicationFiled: August 27, 2018Publication date: September 5, 2019Inventors: Jagat SINGH, Joseph Zev SHAINHOUSE, Bradley S. GALER, Robert Dominic KING-SMITH, Lisa Marie GRIERSON, Maria BURIAN, Jonathan WILKIN, Edward T. KISAK, John M. NEWSAM
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Publication number: 20190255070Abstract: In one example presented herein, is a pharmaceutical composition. The pharmaceutical composition can include halobetasol propionate, from 0 wt % to 3 wt % ethoxylated castor oil, a first compound, and a second compound. The first compound and the second compound can be selected from; N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate, and sodium lauryl sulfoacetate. The first compound and the second compound are not the same.Type: ApplicationFiled: October 21, 2016Publication date: August 22, 2019Applicant: Crescita Therapeutics Inc.Inventors: Wade HULL, Ngoc True-Chi VO, Dominic KING-SMITH
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Patent number: 10058519Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: GrantFiled: May 30, 2017Date of Patent: August 28, 2018Assignee: HZNP LimitedInventors: Jagat Singh, Joseph Zev Shainhouse, Bradley S. Galer, Robert Dominic King-Smith, Lisa Marie Grierson, Maria Burian, Jonathan Wilkin, Edward Kisak, John M. Newsam
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Publication number: 20180147144Abstract: The present invention provides DMSO-containing foamable formulations, methods for preparation, and methods of treatment. The formulations can provide good permeability and bioavailability at the target site. Preferably, the formulations are useful for treating osteoarthritis. In one embodiment, the invention provides a foamable formulation for topical use, said formulation comprising DMSO, polyalkylene glycol alkyl ether, an active agent, a monohydric lower alcohol, a diol, and water. Preferably, the active agent is a non-steroidal anti-inflammatory drug, such as diclofenac sodium or ibuprofen.Type: ApplicationFiled: November 30, 2017Publication date: May 31, 2018Applicant: Nuvo Pharmaceuticals Inc.Inventors: Servet Buyuktimkin, Nadir Buyuktimkin, Edward Kisak, Jagat Singh, John M. Newsam, Dominic King-Smith, Bradley S. Galer
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Publication number: 20180116987Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: ApplicationFiled: May 30, 2017Publication date: May 3, 2018Inventors: Jagat SINGH, Joseph Zev SHAINHOUSE, Bradley S. GALER, Robert Dominic KING-SMITH, Lisa Marie GRIERSON, Maria BURIAN, Jonathan WILKIN, Edward KISAK, John M. NEWSAM
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Patent number: 9861579Abstract: The present invention provides DMSO-containing foamable formulations, methods for preparation, and methods of treatment. The formulations can provide good permeability and bioavailability at the target site. Preferably, the formulations are useful for treating osteoarthritis. In one embodiment, the invention provides a foamable formulation for topical use, said formulation comprising DMSO, polyalkylene glycol alkyl ether, an active agent, a monohydric lower alcohol, a diol, and water. Preferably, the active agent is a non-steroidal anti-inflammatory drug, such as diclofenac sodium or ibuprofen.Type: GrantFiled: July 2, 2015Date of Patent: January 9, 2018Assignee: Nuvo Pharmaceuticals Inc.Inventors: Servet Buyuktimkin, Nadir Buyuktimkin, Edward Kisak, Jagat Singh, John M. Newsam, Dominic King-Smith, Bradley S. Galer
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Publication number: 20170216314Abstract: The present disclosure is drawn to topical formulations and related methods. In one embodiment, a topical formulation is provided that includes an active agent, a first compound, and a second compound. The first compound and second compound are different and each is selected from the group consisting of N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate, and sodium lauryl sulfoacetate.Type: ApplicationFiled: April 19, 2017Publication date: August 3, 2017Inventors: Edward T. Kisak, John M. Newsam, Dominic King-Smith, Pankaj Karande, Samir Mitragotri, Wade A. Hull, Ngoc Truc-Chi Vo
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Patent number: 9642912Abstract: The present disclosure is drawn to topical formulations and related methods. In one embodiment, a topical formulation is provided that includes at least one corticosteroid, a first compound, and a second compound. The first compound and second compound are different and each is selected from the group consisting of N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate, and sodium lauryl sulfoacetate.Type: GrantFiled: December 22, 2014Date of Patent: May 9, 2017Assignee: Crescita Therapeutics Inc.Inventors: Edward T. Kisak, John M. Newsam, Dominic King-Smith, Pankaj Karande, Samir Mitragotri, Wade A. Hull, Ngoc Truc-Chi Vo
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Patent number: 9415029Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: GrantFiled: October 26, 2015Date of Patent: August 16, 2016Assignee: HZNP LimitedInventors: Jagat Singh, Joseph Zev Shainhouse, Bradley S. Galer, Robert Dominic King-Smith, Lisa Marie Grierson, Maria Burian, Jonathan Wilkin, Edward Kisak, John M. Newsam
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Publication number: 20160228392Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: ApplicationFiled: April 13, 2016Publication date: August 11, 2016Inventors: Jagat Singh, Joseph Zev Shainhouse, Bradley S. Galer, Robert Dominic King-Smith, Lisa Marie Grierson, Maria Burian, Jonathan Wilkin, Edward Kisak, Jonathan M. Newsam
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Patent number: 9375412Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: GrantFiled: July 27, 2015Date of Patent: June 28, 2016Assignee: HZNP LimitedInventors: Jagat Singh, Joseph Zev Shainhouse, Bradley S. Galer, Robert Dominic King-Smith, Lisa Marie Grierson, Maria Burian, Jonathan Wilkin, Edward Kisak, John M. Newsam
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Patent number: 9370501Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: GrantFiled: July 21, 2015Date of Patent: June 21, 2016Assignee: HZNP LimitedInventors: Jagat Singh, Joseph Zev Shainhouse, Bradley S. Galer, Robert Dominic King-Smith, Lisa Marie Grierson, Maria Burian, Jonathan Wilkin, Edward Kisak, John M. Newsam
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Patent number: 9308181Abstract: The present disclosure is drawn to topical formulations, transdermal systems, and related methods. In one embodiment, a topical formulation is provided that includes a local anesthetic, a first compound, and a second compound. The first compound and second compound are different and each is selected from the group consisting of N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate, and sodium lauryl sulfoacetate.Type: GrantFiled: March 8, 2013Date of Patent: April 12, 2016Assignee: Nuvo Research Inc.Inventors: Edward T. Kisak, John M. Newsam, Dominic King-Smith, Pankaj Karande, Samir Mitragotri, Tejas Desai, Wade A. Hull
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Publication number: 20160045466Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: ApplicationFiled: October 26, 2015Publication date: February 18, 2016Inventors: Jagat Singh, Joseph Zev Shainhouse, Bradley S. Galer, Robert Dominic King-Smith, Lisa Marie Grierson, Maria Burian, Jonathan Wilkin, Edward Kisak, John M. Newsam
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Publication number: 20150366830Abstract: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.Type: ApplicationFiled: July 21, 2015Publication date: December 24, 2015Inventors: Jagat Singh, Joseph Zev Shainhouse, Bradley S. Galer, Robert Dominic King-Smith, Lisa Marie Grierson, Maria Burian, Jonathan Wilkin, Edward T. Kisak, John M. Newsam
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Publication number: 20150342871Abstract: The present invention provides topical compositions, methods of preparation, and methods of treatment for onychomycosis. In certain specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a zwitterionic surfactant or charged derivative thereof; a carboxylic acid, a lower alcohol, and water. The acid is selected from a short-chain hydroxy acid, a short-chain fatty acid, and a mixture thereof. In certain other specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a quarternary amino acid, a keratolytic agent; a lower alcohol; and water. In certain embodiments, the keratolytic agent is urea, ammonium thioglycolate, or a mixture thereof.Type: ApplicationFiled: June 12, 2015Publication date: December 3, 2015Inventors: Servet Buyuktimkin, Nadir Buyuktimkin, Jagat Singh, John M. Newsam, Dominic King-Smith, Edward T. Kisak