Abstract: Systems and methods for determining a concentration of an analyte in a physiological fluid with a biosensor are presented. Current values are measured during application of voltage pulses across electrodes of the biosensor. Different intermediate analyte concentrations are calculated using different subsets of the measured current values and different scaling factors. A first intermediate analyte concentration has a first level of accuracy across a range of analyte concentrations. A second intermediate analyte concentration has a higher level of accuracy in the low range. A third intermediate analyte concentration has a higher level of accuracy in the high range. The concentration of the analyte is determined as a function of the different intermediate analyte concentrations. The second intermediate analyte concentration, the third intermediate analyte concentration or an average, is selected if the first intermediate analyte concentration is in the low range, the high range or in between, respectively.

Abstract: A method of measuring a sample that includes at least one reactant that can be oxidised and reduced between at least one working electrode and a counter electrode. The method involves: applying across the working and counter electrodes a cycle of at least three pulses, and measuring current at the working electrode during each pulse, wherein the at least three pulses comprise at least one over-potential pulse that has an amplitude equal to or greater than an oxidation or a reduction peak potential of the reactant; at least one under-potential pulse of amplitude less than the at least one over-potential pulse, and at least one other over-potential pulse or under-potential pulse.

Abstract: The invention described herein includes a screen printing process for depositing carbon electrodes including a method for selectively removing components that degrade the electrochemical performance from the surface of said carbon electrodes. In one embodiment of the present invention, the process includes applying a corona treatment to the carbon electrodes.