Patents by Inventor Dominick A. Vacante

Dominick A. Vacante has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8092429
    Abstract: The needle assembly of the invention is a quad-partite system for use with an arc-center stereotactic headframe that allows a clinician to deliver recombinant expression vectors through the needle assembly to targeted sites at exact depths in the brain. Methods for use of the needle assembly with a rube insert for the needle cannula that does not bind proteins, as in protein viral capsids, permit delivery of precise volumes of pharmaceutical compositions containing viral recombinant expression vectors for gene therapy.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: January 10, 2012
    Assignee: Ceregene, Inc.
    Inventors: Mehdi Gasmi, Elias T. Ketchum, Dominick A. Vacante
  • Publication number: 20110060285
    Abstract: The needle assembly of the invention is a quad-partite system for use with an arc-center stereotactic headframe that allows a clinician to deliver recombinant expression vectors through the needle assembly to targeted sites at exact depths in the brain. Methods for use of the needle assembly with a rube insert for the needle cannula that does not bind proteins, as in protein viral capsids, permit delivery of precise volumes of pharmaceutical compositions containing viral recombinant expression vectors for gene therapy.
    Type: Application
    Filed: November 10, 2010
    Publication date: March 10, 2011
    Inventors: Mehdi Gasmi, Elias T. Ketchum, Dominick A. Vacante
  • Patent number: 7837668
    Abstract: The needle assembly of the invention is a quad-partite system for use with an arc-center stereotactic headframe that allows a clinician to deliver recombinant expression vectors through the needle assembly to targeted sites at exact depths in the brain. Methods for use of the needle assembly with a tube insert for the needle cannula that does not bind proteins, as in protein viral capsids, permit delivery of precise volumes of pharmaceutical compositions containing viral recombinant expression vectors for gene therapy.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: November 23, 2010
    Assignee: Ceregene, Inc.
    Inventors: Mehdi Gasmi, Elias T. Ketchum, Dominick A. Vacante
  • Publication number: 20080086061
    Abstract: The needle assembly of the invention is a quad-partite system for use with an arc-center stereotactic headframe that allows a clinician to deliver recombinant expression vectors through the needle assembly to targeted sites at exact depths in the brain. Methods for use of the needle assembly with a tube insert for the needle cannula that does not bind proteins, as in protein viral capsids, permit delivery of precise volumes of pharmaceutical compositions containing viral recombinant expression vectors for gene therapy.
    Type: Application
    Filed: October 10, 2006
    Publication date: April 10, 2008
    Inventors: Mehdi Gasmi, Elias T. Ketchum, Dominick A. Vacante