Abstract: A clutch assembly for the powertrain of a motor vehicle, including a housing, a support which is supported in a rotatable manner relative to the housing, an electric machine, the rotor of which is received on the support in a rotationally fixed manner, multiple clutches, each having a clutch component that is received on the support in a rotationally fixed manner, and at least one slave cylinder which acts on one clutch in an actuating manner. A first support bearing which forms part of the mounting of the support is arranged directly between the support and the housing, and an additional second support bearing is arranged at a distance from the first support bearing along a rotational axis of the support. A drive unit including the clutch assembly is also provided.

Abstract: The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.

Abstract: The present invention relates to regioselective chemical and electrochemical processes for the preparation of an oxidized heterocyclic alpha-amino amide compounds. By applying specific catalysts or catalyst systems during chemical oxidation or by applying particular electrochemical oxidation conditions the present invention provides access to valuable alpha amino amide compounds, which are oxidized at the heterocyclic amino group by regioselective introduction of either a hydroxyl or a keto group. In a more particular embodiment, the present invention describes a chemical oxidation reaction, which advantageously is applicable in the enantioselective synthesis of valuable oxidized heterocyclic alpha-amino amide compounds, like levetiracetam, brivaracetam or the synthesis of piracetam. Another aspect of the present invention relates to a process for the electrochemical recycling of alkali perhalogenate oxidants as spent during said regioselective oxidation reactions of the invention.

Abstract: A conducting element for conducting a pressurized fluid and for conducting a cooling fluid, as well as a hybrid module and a drive assembly having a hybrid module are provided. The conducting element for conducting a pressurized fluid for hydraulically actuating a clutch unit and for conducting cooling fluid for cooling a clutch unit has a cylindrical section and a securing section. At least one pressurized fluid channel is formed in the securing section for transporting pressurized fluid. The conducting element also has at least one cooling fluid channel which has at least one axial direction component in the cylindrical section, wherein the flow line element is fluidically connected to the cooling fluid channel for supplying a clutch unit and/or electric machine with cooling fluid.