Patents by Inventor Dominika Pcion

Dominika Pcion has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of an antiviral compound
    Patent number: 10030033
    Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: July 24, 2018
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Amy Cagulada, Johann Chan, Lina Chan, Denise A. Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondappally, Chris Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J. Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G. Taylor, Jonathan Tripp, Andrew W. Waltman, Lawrence Yu
  • Crystalline forms of an antiviral compound
    Patent number: 9862728
    Abstract: Crystalline forms of the anti-HCV compound (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-18,18-difluoro-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: January 9, 2018
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Dustin Bringley, Johann Chan, Peter Fung, Katie Keaton, Olga Lapina, Henry Morrison, Dominika Pcion
  • CRYSTALLINE FORMS OF AN ANTIVIRAL COMPOUND
    Publication number: 20170267694
    Abstract: Crystalline forms of the anti-HCV compound (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-18,18-difluoro-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.
    Type: Application
    Filed: December 21, 2016
    Publication date: September 21, 2017
    Inventors: Dustin Bringley, Johann Chan, Peter Fung, Katie Keaton, Olga Lapina, Henry Morrison, Dominika Pcion
  • SYNTHESIS OF AN ANTIVIRAL COMPOUND
    Publication number: 20170210756
    Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.
    Type: Application
    Filed: August 3, 2016
    Publication date: July 27, 2017
    Inventors: Amy Cagulada, Johann Chan, Lina Chan, Denise A. Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondapally, Christopher Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J. Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G. Taylor, Jonathan Tripp, Andrew W. Waltman, Lawrence Yu
  • Crystalline forms of an antiviral compound
    Patent number: 9562058
    Abstract: Crystalline forms of the anti-HCV compound (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-18,18-difluoro-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: February 7, 2017
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Dustin Bringley, Johann Chan, Peter Fung, Katie Keaton, Olga Lapina, Henry Morrison, Dominika Pcion
  • Synthesis of an antiviral compound
    Patent number: 9440991
    Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: September 13, 2016
    Assignee: Gilead Sciences, Inc.
    Inventors: Amy Cagulada, Johann Chan, Lina Chan, Denise A. Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondapally, Chris Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J. Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G. Taylor, Jonathan Tripp, Andrew W. Waltman, Lawrence Yu
  • SYNTHESIS OF AN ANTIVIRAL COMPOUND
    Publication number: 20150175626
    Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.
    Type: Application
    Filed: December 18, 2014
    Publication date: June 25, 2015
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Amy Cagulada, Johann Chan, Lina Chan, Denise A. Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondapally, Chris Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J. Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G. Taylor, Jonathan Tripp, Andrew W. Waltman, Lawrence Yu
  • CRYSTALLINE FORMS OF AN ANTIVIRAL COMPOUND
    Publication number: 20150175625
    Abstract: Crystalline forms of the anti-HCV compound (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-18,18-difluoro-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.
    Type: Application
    Filed: December 18, 2014
    Publication date: June 25, 2015
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Dustin Bringley, Johann Chan, Peter Fung, Katie Keaton, Olga Lapina, Henry Morrison, Dominika Pcion
  • Process and intermediates for preparing integrase inhibitors
    Patent number: 8877931
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: November 4, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Dominika Pcion, Carrie Tomasi, Mark Charles Whitcomb, Eric D. Dowdy, Wenyi Fu, Patricia MacLeod
  • PROCESS AND INTERMEDIATES FOR PREPARING INTEGRASE INHIBITORS
    Publication number: 20140039194
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 6, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Dominika PCION, Carrie TOMASI, Mark Charles WHITCOMB, Eric D. DOWDY, Wenyi FU, Patricia MACLEOD
  • Processes and intermediates useful for preparing integrase inhibitor compounds
    Publication number: 20080039487
    Abstract: The invention provides processes and intermediates useful for preparing integrase inhibiting compounds.
    Type: Application
    Filed: December 21, 2006
    Publication date: February 14, 2008
    Inventors: Jared Evans, Jay Parrish, Dominika Pcion, Richard Polniaszek, Christina Schmidt, Richard Yu, Vahid Zia