Patents by Inventor Dominique Bonnet

Dominique Bonnet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METABOLICALLY STABLE PEPTIDE ANALOGS
    Publication number: 20230173076
    Abstract: The present invention relates to metabolically stable and non-immunogen analogs completely hydrosoluble at physiological pH, and their use for the prevention or treatment of diseases mediated by G-protein coupled receptor (GPCR), in particular (Central Nervous System) CNS and cardiovascular diseases or disorders, or their use in diagnostic methods.
    Type: Application
    Filed: October 19, 2022
    Publication date: June 8, 2023
    Inventors: Dominique BONNET, Catherine LLORENS CORTES, Xavier ITURRIOZ
  • FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS
    Publication number: 20230174480
    Abstract: The present disclosure relates to a novel fluorogenic dimer compound, useful as a probe for detection of endogenous receptors, in particular G protein-coupled receptors. The present invention provides compositions and kits comprising such compound and methods of labeling a biomolecule, comprising the step of contacting the biomolecule with the compound of the invention.
    Type: Application
    Filed: May 12, 2021
    Publication date: June 8, 2023
    Inventors: JULIE KARPENKO, ANDREY KLYMCHENKO, DOMINIQUE BONNET, MAYEUL COLLOT
  • Antigen Delivery Vectors and Constructs
    Publication number: 20220073446
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
    Type: Application
    Filed: July 19, 2021
    Publication date: March 10, 2022
    Applicant: Altimmune UK Limited
    Inventors: Dominique Bonnet, Carlton B Brown, Bertrand V. Georges, Philip J Sizer
  • INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS
    Publication number: 20210316000
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans.
    Type: Application
    Filed: November 11, 2018
    Publication date: October 14, 2021
    Applicant: Altimmune UK Limited
    Inventors: Dominique Bonnet, Carlton Brown, Bertrand Georges, Philip Sizer
  • Antigen delivery vectors and constructs
    Patent number: 11066353
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: July 20, 2021
    Assignee: Altimmune UK Ltd
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand V. Georges, Philip J. Sizer
  • Metabolically Stable Apelin Analogs in the Treatment of Disease Mediated by the Apelin Receptor
    Publication number: 20210206817
    Abstract: The invention is related to metabolically stable apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin receptor in particular of cardiovascular disease (heart failure, hypertension, pulmonary hypertension, kidney failure) and inappropriate vasopressin secretions (SIADH).
    Type: Application
    Filed: March 12, 2021
    Publication date: July 8, 2021
    Inventors: Catherine LLORENS-CORTES, Dominique BONNET, Xavier ITURRIOZ
  • Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines
    Patent number: 11046657
    Abstract: A subject of the present invention is a compound having the general formula (I): a pharmaceutically acceptable salt thereof or a tautomeric form thereof, wherein A, B3, B4, B5, Y, X, B1 and B2 are as defined in any one of claims 1 to 10. Another subject of the invention is the compound as defined above for use as a medicament, in particular for preventing and/or treating inflammation and inflammatory diseases, immune and auto-immune diseases, pain related diseases, genetic diseases and/or cancer.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: June 29, 2021
    Assignees: Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale, Universite de Strasbourg, Universite Paris-Sud, Centre International de Recherche aux Frontieres de la Chimie
    Inventors: Dominique Bonnet, Nelly Frossard, Jean-Luc Galzi, Christophe Guignabert, Marcel Hibert, Frédéric Simonin, Sylviane Muller
  • Pyrimidinone Derivatives and Uses Thereof to Neutralize the Biological Activity of Chemokines
    Publication number: 20200181093
    Abstract: A subject of the present invention is a compound having the general formula (I): a pharmaceutically acceptable salt thereof or a tautomeric form thereof, wherein A, B3, B4, B5, Y, X, B1 and B2 are as defined in any one of claims 1 to 10. Another subject of the invention is the compound as defined above for use as a medicament, in particular for preventing and/or treating inflammation and inflammatory diseases, immune and auto-immune diseases, pain related diseases, genetic diseases and/or cancer.
    Type: Application
    Filed: July 13, 2017
    Publication date: June 11, 2020
    Applicants: Centre National de la Recherche Scientifique (CNRS, Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Strasbourg, Universite Paris-Sud, Centre International de Recherche aux Frontieres d e la Chimie
    Inventors: Dominique Bonnet, Nelly Frossard, Jean-Luc Galzi, Christophe Guignabert, Marcel Hibert, Frédéric Simonin, Sylviane Muller
  • METABOLICALLY STABLE PEPTIDE ANALOGS
    Publication number: 20190328887
    Abstract: The present invention relates to metabolically stable and non-immunogen analogs completely hydrosolubleat physiological pH, and their use for the prevention or treatment of diseases mediated by G-protein coupled receptor (GPCR), in particular (Central Nervous System) CNS and cardiovascular diseases or disorders, or their use in diagnostic methods.
    Type: Application
    Filed: June 16, 2017
    Publication date: October 31, 2019
    Inventors: Dominique BONNET, Catherine LLORENS CORTES, Xavier ITURRIOZ
  • INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS
    Publication number: 20190142951
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans.
    Type: Application
    Filed: November 11, 2018
    Publication date: May 16, 2019
    Applicant: Altimmune UK Limited
    Inventors: Dominique Bonnet, Carlton Brown, Bertrand Georges, Philip Sizer
  • METABOLICALLY STABLE SPEXIN PEPTIDE ANALOGS
    Publication number: 20190135887
    Abstract: The present invention concerns metabolically stable and non-immunogen spexin analogs that are completely hydrosoluble at physiological pH, and their use for the prevention or the treatment of diseases mediated by the GALR2 receptor.
    Type: Application
    Filed: June 16, 2017
    Publication date: May 9, 2019
    Inventors: Dominique BONNET, Frédéric SIMONIN, Glenn-Marie LE COZ, Lucie ESTÉOULLE
  • Influenza antigen delivery vectors and constructs
    Patent number: 10155049
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: December 18, 2018
    Assignee: Altimmune UK, LTD
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand V. Georges, Philip J. Sizer
  • Metabolically Stable Apelin Analogs in the Treatment of Disease Mediated by the Apelin Receptor
    Publication number: 20170355734
    Abstract: The invention is related to metabolically stable apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin receptor in particular of cardiovascular disease (heart failure, hypertension, pulmonary hypertension, kidney failure) and inappropriate vasopressin secretions (SIADH).
    Type: Application
    Filed: December 23, 2015
    Publication date: December 14, 2017
    Inventors: Catherine LLORENS-CORTES, Dominique BONNET, Xavier ITURRIOZ
  • INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS
    Publication number: 20170049898
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans.
    Type: Application
    Filed: August 22, 2016
    Publication date: February 23, 2017
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand V. Georges, Philip J. Sizer
  • Influenza antigen delivery vectors and constructs
    Patent number: 9446143
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: September 20, 2016
    Assignee: ALTIMMUNE UK LIMITED
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand Victor Gilbert Georges, Philip J. Sizer
  • Antigen Delivery Vectors and Constructs
    Publication number: 20150112042
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
    Type: Application
    Filed: May 23, 2014
    Publication date: April 23, 2015
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand V. Georges, Philip J. Sizer
  • INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS
    Publication number: 20140234356
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans.
    Type: Application
    Filed: December 23, 2013
    Publication date: August 21, 2014
    Applicant: IMMUNE TARGETING SYSTEMS LTD.
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand Victor Gilbert Georges, Philip J. Sizer
  • Antigen delivery vectors and constructs
    Patent number: 8759281
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
    Type: Grant
    Filed: January 20, 2012
    Date of Patent: June 24, 2014
    Assignee: Immune Targeting Systems Ltd.
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand Georges, Philip J. Sizer
  • Influenza antigen delivery vectors and constructs
    Patent number: 8642531
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: February 4, 2014
    Assignee: Immune Targeting Systems Ltd.
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand Georges, Philip J. Sizer
  • Antigen Delivery Vectors and Constructs
    Publication number: 20120315293
    Abstract: The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
    Type: Application
    Filed: January 20, 2012
    Publication date: December 13, 2012
    Inventors: Dominique Bonnet, Carlton B. Brown, Bertrand Georges, Philip J. Sizer