Patents by Inventor Dominique Brassart

Dominique Brassart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190142878
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Application
    Filed: January 14, 2019
    Publication date: May 16, 2019
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Patent number: 10213466
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: February 26, 2019
    Assignee: Probioswiss Ag
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20180143186
    Abstract: Described is a matrix to identify mother's milk missing fucosyltransferase-2 (FUT2) dependent glycans which comprise a line of a glycan binding protein such as a lectin or antibody suitable to bind 2?fucosyl-glycans and a line of a positive control to bind a mother's milk protein. For instance, this matrix is porous and allows for transport by capillary force of compounds of mother's milk such as glycoproteins. Especially, the glycan binding protein is the plant lectin from Ulex europaeus. A diagnostic kit comprising one or more of such matrices and a device suitable to receive such a matrix provided with a milk application window and a read-out window has been described as well. Finally a kit-of-parts comprising such a diagnostic kit and one or more feeding doses of 2?fucosyl-glycans has been disclosed.
    Type: Application
    Filed: May 18, 2016
    Publication date: May 24, 2018
    Inventors: Dominique Brassart, Norbert Sprenger
  • Publication number: 20180078572
    Abstract: The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide, for use in preventing and/or treating constipation and/or in improving stool consistency/frequency in an infant or a young child.
    Type: Application
    Filed: March 4, 2016
    Publication date: March 22, 2018
    Inventors: Norbert Sprenger, Dominique Brassart, Delphine Egli
  • Publication number: 20180078573
    Abstract: The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide for use in preventing and/or treating constipation and/or in improving stool consistency/frequency in an infant or a young child.
    Type: Application
    Filed: March 4, 2016
    Publication date: March 22, 2018
    Inventors: Norbert Sprenger, Dominique Brassart, Delphine Egli
  • Publication number: 20180042949
    Abstract: The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide in particular amounts, for use in preventing and/or treating infections and/or inflammations of the lower respiratory tract and/or of the ear in an infant or a young child.
    Type: Application
    Filed: March 4, 2016
    Publication date: February 15, 2018
    Inventors: Norbert Sprenger, Dominique Brassart, Delphine Egli
  • Publication number: 20180036323
    Abstract: The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide in a particular ratio, for use in preventing and/or treating gastrointestinal infections and/or gastrointestinal inflammations in an infant or a young child.
    Type: Application
    Filed: March 4, 2016
    Publication date: February 8, 2018
    Inventors: Norbert Sprenger, Dominique Brassart, Delphine Egli
  • Patent number: 9827216
    Abstract: The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or neoplasm, between cycles of and after anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject tumor-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to treatment; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened due to paralysis of the bone marrow, caused by a tumor or neoplasm.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: November 28, 2017
    Assignees: Nestec S.A., Institut Curie
    Inventors: Eduardo Schiffrin, Kevin Burke Miller, Dominique Brassart, Olivier Jacques Lantz, Sebastian Diego Amigorena
  • Publication number: 20170027998
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Application
    Filed: October 12, 2016
    Publication date: February 2, 2017
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20160296543
    Abstract: The present invention relates to a composition comprising at least one fucosylated oligosaccharide, for use in preventing allergies and/or treating allergies and/or reducing the occurrence or the risk of allergies in an infant or a young child born from a mother deficient in at least one fucosylated oligosaccharide(s) or fed with a mother's milk deficient in at least one fucosylated oligosaccharide(s). The use of said composition in infant formula, milk fortifier or children's food is foreseen.
    Type: Application
    Filed: November 4, 2014
    Publication date: October 13, 2016
    Applicant: NESTEC S.A.
    Inventors: Dominique Brassart, Clemens Kunz, Norbert Sprenger
  • Publication number: 20160287618
    Abstract: The present invention relates to a composition comprising at least one fucosylated oligosaccharide, for use in preventing and/or treating URT infections in an infant or young child fulfilling at least one of the following criteria: i) the infant or young child is born from a non-secretor mother and/or is fed with a mother's milk deficient in at least one fucosylated oligosaccharide(s) ii) the infant or young child has at least one sibling iii) the infant or young child was born by C-section.
    Type: Application
    Filed: November 14, 2014
    Publication date: October 6, 2016
    Applicant: NESTEC S.A.
    Inventors: Norbert Sprenger, Clemens Kunz, Dominique Brassart
  • Publication number: 20140248415
    Abstract: A method for the manufacture an infant formula or an infant nutritional product comprising mixture of human milk oligosaccharides is disclosed. The method involves the catalytic hydrogenolysis of compounds of the general formula 1 and 2 with particular oligosaccharide profiles.
    Type: Application
    Filed: May 10, 2012
    Publication date: September 4, 2014
    Applicant: NESTEC S.A.
    Inventors: Dominique Brassart, Gyula Dekany, Peter Erdmann, Andrea Schwarz, Norbert Sprenger
  • Publication number: 20110229521
    Abstract: The present invention relates to methods and immunonutritional compositions for preventing the impairment of the immune function during anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently augment or enhance the immunocompetence of an immune cell and the immunogenecity of a tumor cell of a subject undergoing anti-cancer therapy-induced apoptosis and tumor-cell-enhanced immunogenicity such that the innate and adaptive immune functions and normal physiology of the immune cell are preserved, which, in turn, lead to (i) a better tolerance and increased efficacy to anti-cancer therapy; (ii) transient augmentation or enhancement of immunocompetence of the immune cell and immunogenecity of the tumor cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened by anti-cancer therapy.
    Type: Application
    Filed: September 11, 2009
    Publication date: September 22, 2011
    Inventors: Eduardo Schiffrin, Kevin Burke Miller, Dominique Brassart
  • Publication number: 20110229447
    Abstract: The present invention relates to methods and immunonutritional compositions for preventing the impairment of the immune function during anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject undergoing anti-cancer therapy-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to anti-cancer therapy; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened by anti-cancer therapy.
    Type: Application
    Filed: September 11, 2009
    Publication date: September 22, 2011
    Inventors: Eduardo Schiffrin, Kevin Burke Miller, Dominique Brassart
  • Publication number: 20110223136
    Abstract: The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or neoplasm, between cycles of and after anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject tumor-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to treatment; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened due to paralysis of the bone marrow, caused by a tumor or neoplasm.
    Type: Application
    Filed: September 11, 2009
    Publication date: September 15, 2011
    Inventors: Eduardo Schiffrin, Kevin Burke Miller, Dominique Brassart, Olivier Jacques Lantz, Sebastian Diego Amigorena
  • Publication number: 20100196340
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Application
    Filed: October 17, 2005
    Publication date: August 5, 2010
    Applicant: BDN BIO SARL
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20080131462
    Abstract: The invention relates to a method for preventing or treating gastrointestinal infections in humans, which comprises administering a pharmaceutical preparation comprising, in combination with a pharmaceutically acceptable or food grade carrier, a therapeutically effective amount of at least one lactic acid bacteria strain of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii selected for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within gastrointestinal epithelial cells.
    Type: Application
    Filed: April 20, 2007
    Publication date: June 5, 2008
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20080019954
    Abstract: The invention relates to a method for preventing or treating urogenital infections in females, which comprises administering a pharmaceutical preparation comprising, in combination with a suitable galenical carrier, a therapeutically effective amount of at least one lactic acid bacteria strain of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii selected for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within vaginal epithelial cells, as well as for their ability to modulate a humoral and/or cellular immune response at the vaginal and/or gastrointestinal level, in particular to inhibit the inflammatory syndrome as well as the infectious syndrome.
    Type: Application
    Filed: April 20, 2007
    Publication date: January 24, 2008
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Patent number: 6489310
    Abstract: An enteral composition which contains a protein source, a lipid source, a carbohydrate source, and a fibre blend. The fibre blend contains inulin and fructo-oligosaccharides and has 45 to 55% by weight of the blend of soluble fibre and 45 to 55% by weight of the blend of insoluble fibre. The fibre blend may also contain pea inner fibres and pea outer envelope fibres.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: December 3, 2002
    Assignee: Nestec S.A.
    Inventors: Dominique Brassart, Veronique Jaussan, Thomas Schweizer, Thierry Brun
  • Publication number: 20020127211
    Abstract: A method for increasing or facilitating the absorption of minerals from the diet. A nutritional composition which contains lactobacilli is enterally administered to a mammal. The nutritional composition is suitable for the treatment or prophylaxis of sutjects having mineral deficiencies, or to compensate for physiological deficiencies due to a diet low in minerals, or to satisfy major physiological requirements for minerals in young children. pregnant women, women who are breastieeding, and the elderly.
    Type: Application
    Filed: March 13, 2000
    Publication date: September 12, 2002
    Inventors: DOMINIQUE BRASSART, ELISABETH VEY