Abstract: A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the penetrating member driver. A support is provided with a plurality of openings. Each opening receives a penetrating member.

Abstract: A body fluid sampling system for use on a tissue site includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation.

Abstract: A tissue penetrating system includes a plurality of cartridges each with a distal port and a proximal port. A plurality of penetrating members are provided, each coupled to a cartridge and having a sharpened distal tip and a shaft portion slidably disposed within the cartridge. A seal is formed by a fracturable material between the penetrating member and the cartridge. The seal is positioned at one or both of a distal port or a proximal port of the cartridge.

Abstract: These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. The drive force generator is configured to be controlled to follow a predetermined velocity trajectory into the tissue and out of the tissue. A tissue stabilizing member is associated with the device and at least partially surrounds an impact location of the penetrating member on the tissue site.

Abstract: A body fluid sampling system for use on a tissue site includes a drive force generator. A plurality of penetrating members are housed in a penetrating member housing. Each of penetrating member is configured to be coupled to the drive force generator. A plurality of analyte sensors are housed in an analyte sensor housing. Each analyte sensor is associated with a penetrating member. The analyte sensor housing is in a surrounding relationship to the penetrating member housing and positioned to provide that upon launch of a penetrating member, and penetration of a penetrating member at a skin surface, blood flows into the analyte sensor.

Abstract: A device is provided for fluid delivery. The device comprises a cartridge having a plurality of cavities and a plurality of penetrating members. The plurality of penetrating members are each at least partially contained in cavities of the cartridge wherein the penetrating members are slidably movable to extend outward from openings on said cartridge to penetrate tissue. Each of the penetrating members comprises a needle with a lumen coupled to a canister containing a material to be injected.

Abstract: In one embodiment according to the present invention, a device is provided comprising a cartridge having a plurality of cavities. The device may include a plurality of penetrating members at least partially contained in the cavities of the single cartridge wherein the penetrating members are slidably movable to extend outward from lateral openings on the cartridge to penetrate tissue. The device may have a sterility barrier coupled to the cartridge, wherein the sterility barrier covers a plurality of the lateral openings, and wherein the sterility barrier covering the lateral openings is configured to be moved so that a penetrating member exits the lateral opening without contacting the barrier. The device may include a plurality of analyte detecting members coupled to the cartridge and a plurality of sample capture devices, wherein the sample capture devices each having an opening there through to allow a penetrating member to pass through.

Abstract: A body fluid sampling system is provided for use on a tissue site. In one embodiment, the system comprises a cartridge; a penetrating member driver; a plurality of penetrating members arranged in a radial configuration on the cartridge wherein sharpened distal tips of the penetrating members point radially outward; wherein an active one of the penetrating members may be operatively coupled to the penetrating member driver, the penetrating member driver moving the active one along a path out of a housing having a penetrating member exit, into the tissue site, stopping in the tissue site, and withdrawing out of the tissue site; and a plurality of analyte detecting members, wherein at least one of the analyte detecting members is positioned to receive fluid from a wound created by the active one of the penetrating members, wherein the detecting members are not pierced by the active one of the penetrating members.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver comprises of a drive force generator for advancing the lancet along a path into the tissue site, and a sensor configured to detect lancet position along said path during the lancing cycle.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: A method is provided for controlling a lancet velocity profile. A velocity of a moving lancet is measured at a known position. The measured velocity of the lancet is compared with an appropriate velocity for the lancet at the known position. A force is applied to the lancet to adjust the velocity of the lancet.

Abstract: A body fluid sampling system for use on a tissue site has a housing and a penetrating member driver at least partially within the housing. At least one cartridge is in the housing. The cartridge includes an analyte sensor in a sample chamber configured to receive body fluid from a wound in tissue created by a penetrating member. A penetrating member is associated with the sample chamber. Each penetrating member, and its associated sample chamber, has a combined occupied volume of no more than about 5.0 cm3. The penetrating member is at least partially co-located with the analyte sensor in the sample chamber. The sample chamber receives body fluid from a wound in tissue created by a penetrating member, and the analyte sensor determines analyte levels using a body fluid sample of less than about 1 microliter. A transport mechanism engages the cartridge. The penetrating member is operatively engaged with the penetrating member driver when moved into position by the transport mechanism.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: A tissue penetrating system is provided. The system may include a housing, a penetrating members positioned in the housing, and a visual display on the housing, the visual display having at lease one visual indicator positioned next to a corresponding marking on the housing. In one embodiment, the visual display may provide a variety of information about the function and performance of the penetrating member.

Abstract: A plurality of Point-of-Care (POC) tests on a single cartridge (300) is provided such that sequential or nonsequential tests may be performed in an integrated fashion without changing the test cartridge. Each cartridge can contain a penetrating member sensor (302) combination in a radial disk format, interrogated and read by a single illumination/detection device. Alternatively a series of tests can be measured electrochemically and reported. Only those tests, which are required at the time, the sample is taken need to be reported, though all tests are carried out.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: A body fluid sampling system is provided for use on a tissue site. A container has at least one guide chamber and a driver. A plurality of penetrating members are included. At least one sample receiving unit is configured to be coupled to the driver and advanced out of the guide chamber of the container and receiving body fluid at a receiving site. A penetrating member is integrated with the sample receiving unit to carry out a lancing movement towards a body part containing the body fluid.