Patents by Inventor Dominique Manechez

Dominique Manechez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide compounds analogues of the glucagon-like peptide-1 (7-37)
    Patent number: 6620910
    Abstract: Compound of formula (I): Z1-X1-X2-X3-Gly-Thr-Phe-Thr-Ser-X4-X5-Ser-X6-X7-X8  (I) wherein: Z1, substituent of the terminal amino group, represents hydrogen, alkyl or acyl, or arylcarbonyl, heteroarylcarbonyl, arylalkylcarbonyl, heteroarylcarbonyl, aryloxycarbonyl, arylalkoxycarbonyl or alkoxycarbonyl each of which is optionally substituted, Z2 (SEQ ID NO: 1), substituent of the terminal carbonyl group, represents hydroxy, alkoxy or optionally substituted amino, X1 to X14 each represents an amino acid residue having the D or L configuration as defined in the description, X15 represents a bond or an arginine residue (Arg). Medicinal products containing the same are useful as tGLP-1 agonists.
    Type: Grant
    Filed: March 15, 1999
    Date of Patent: September 16, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Bernard Calas, Gérard Grassy, Alain Chavanieu, Cyril Sarrauste de Menthiere, Pierre Renard, Bruno Pfeiffer, Dominique Manechez
  • Imidazoline compounds
    Patent number: 5925665
    Abstract: Compound of formula (I): in which R is as defined in the description, as well as their isomers and their pharmaceutically acceptable acid additions salts. Medicinal products containing the same are useful as Imidazoline receptors ligand.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: July 20, 1999
    Assignee: Adir Et Compagnie
    Inventors: Marc Payard, Saadia Danoun, Genevieve Baziard-Mouysset, Maria Anastassiadou, Daniel-Henri Caignard, Pierre Renard, Dominique Manechez, Elizabeth Scalbert, Marie-Claire Rettori
  • Benzopyran compounds
    Patent number: 5889045
    Abstract: A compound of formula (I): ##STR1## in which: R.sub.1 represents alkyl,R.sub.2, R.sub.4 and R.sub.5, which may be identical or different, represent hydrogen or alkyl,R.sub.3 represents any one of the groups as defined in the description,X represents carbonyl or methylene,Y represents hydrogen or alkyl or aryl,A represents single bond or alkylphenyl,R.sub.6 represents any one of the groups as defined in the description, its isomers as well as its addition salts with a pharmaceutically acceptable acid or base,and medicinal productes containing the same are useful in the treatment of diabetes and complications of diabetic disease.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: March 30, 1999
    Assignee: Adir et Compagnie
    Inventors: Timothee Muller, Claudie Moulin, Muriel Duflos, Sylvie Robert-Piessard, Guillaume Le Baut, Alain Tonnerre, Daniel-Henri Caignard, Dominique Manechez, Pierre Renard
  • (Thia) cycloalkyl[B]indole compounds as anti-inflammatory agents
    Patent number: 5635516
    Abstract: A compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description.
    Type: Grant
    Filed: June 27, 1995
    Date of Patent: June 3, 1997
    Assignee: Adir et Compagnie
    Inventors: Paul Caubere, Brigitte Jamart-Gregoire, Catherine Caubere, Dominique Manechez, Pierre Renard, Gerard Adam, Catherine Nguyen