Patents by Inventor Dominique Mazier

Dominique Mazier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Determining the Susceptibility of a Cell Strain to Drugs
    Publication number: 20120276577
    Abstract: The present invention relates to a method for determining the susceptibility of a cell strain to a compound intended for controlling the growth of said cell strain, comprising: growing the cell strain in a first compound-free culture medium and in at least a second culture medium comprising the compound at a test concentration; obtaining mass-spectrometry spectra for a protein extract of the cell strain grown in the first culture medium and for a protein extract of the cell strain grown in the second culture medium; comparing the mass spectrometry spectra; deducing that the cell strain is sensitive to the compound at the test concentration if the mass spectrometry spectra are significantly different.
    Type: Application
    Filed: June 25, 2010
    Publication date: November 1, 2012
    Applicants: ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Dominique Mazier, Carine Marinach-Patrice, Alexandre Alanio, Jean L. Golmard, Martine Palous, Annick Datry, Jean Y. Brossas
  • Compounds for Preventing and Treating Plasmodium Infections
    Publication number: 20110124723
    Abstract: The present invention relates to the use of at least one compound of formula (I) for the manufacture of a medicament intended for preventing or treating infections by a Plasmodium parasite in an individual, by inhibiting the pre-erythrocytic development stage of said Plasmodium parasite.
    Type: Application
    Filed: December 11, 2008
    Publication date: May 26, 2011
    Applicants: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), UNIVERSITE PARIS DIDEROT - PARIS 7, UNIVERSITAT DE VALENCIA, ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
    Inventors: Dominique Mazier, Nassira Mahmoudi, Khémaïs Farhati, Ramon Garcia-Domenech, Jorge Galvez, Francis Derouin, Martin Danis
  • Alkaloid compounds and their use as anti-malarial drugs
    Patent number: 7943633
    Abstract: Anti-malarial alkyloid compounds have the formula: wherein R1-R11 have various disclosed values or their pharmaceutically acceptable salts, and pharmaceutical compositions containing the same.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: May 17, 2011
    Assignees: Universite Pierre et Marie Curie (Paris VI), Centre National de la Recherche Scientifique, Museum National d'Histoire Naturelle, Institut Malgache de Recherche Appliquee
    Inventors: François Frappier, Marie-Pierre Frappier, legal representative, Jérôme Frappier, legal representative, Dominique Mazier, Maëlle Carraz, Jean-François Franetich, Akino Jossang, Roger Joyeau, Phillippe Rasoanaivo
  • PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF PROTOZOAN PARASITIC DISEASES
    Publication number: 20090203678
    Abstract: The present invention relates to the use of a Rho/ROCK/PI3K/Akt pathway modulator for the manufacture of a medicament intended for the prevention or the treatment of pathologies associated with an infection by a protozoan parasite.
    Type: Application
    Filed: August 2, 2007
    Publication date: August 13, 2009
    Applicant: UNIVERSITE PIERRE ET MARIE CURIE-PARIS VI
    Inventors: Dominique Mazier, Zacharie Taoufiq, Liliane Ciceron, Paco Pino
  • Alkaloid compounds and their use as anti-malarial drugs
    Publication number: 20080038390
    Abstract: Anti-malarial alkyloid compounds have the formula: wherein R1-R11 have various disclosed values or their pharmaceutically acceptable salts, and pharmaceutical compositions containing the same.
    Type: Application
    Filed: October 20, 2006
    Publication date: February 14, 2008
    Inventors: Francois Frappier, Marie-Pierre Frappier, Jerome Frappier, Dominique Mazier, Maelle Carraz, Jean-Francois Franetich, Akino Jossang, Roger Joyeau, Phillippe Rasoanaivo