Patents by Inventor Dominique Melon Manguer

Dominique Melon Manguer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof
    Patent number: 10980816
    Abstract: The present invention relates to compounds of formula (1): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: April 20, 2021
    Assignee: Sanofi
    Inventors: Jean-Christophe Carry, Fabienne Chatreaux, Stephanie Deprets, Olivier Duclos, Vincent Leroy, Sergio Mallart, Dominique Melon-Manguer, Maria Mendez-Perez, Fabrice Vergne
  • NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
    Publication number: 20200323874
    Abstract: The present invention relates to compounds of formula (1): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Application
    Filed: June 29, 2020
    Publication date: October 15, 2020
    Inventors: Jean-Christophe CARRY, Fabienne CHATREAUX, Stephanie DEPRETS, Olivier DUCLOS, Vincent LEROY, Sergio MALLART, Dominique MELON-MANGUER, Maria MENDEZ-PEREZ, Fabrice VERGNE
  • Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof
    Patent number: 10736904
    Abstract: The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: August 11, 2020
    Assignee: SANOFI
    Inventors: Jean-Christophe Carry, Fabienne Chatreaux, Stephanie Deprets, Olivier Duclos, Vincent Leroy, Sergio Mallart, Dominique Melon-Manguer, Maria Mendez-Perez, Fabrice Vergne
  • NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
    Publication number: 20200078370
    Abstract: The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Application
    Filed: October 30, 2019
    Publication date: March 12, 2020
    Inventors: Jean-Christophe CARRY, Fabienne CHATREAUX, Stephanie DEPRETS, Olivier DUCLOS, Vincent LEROY, Sergio MALLART, Dominique MELON-MANGUER, Maria MENDEZ-PEREZ, Fabrice VERGNE
  • Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof
    Patent number: 10500212
    Abstract: The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: December 10, 2019
    Assignee: SANOFI
    Inventors: Jean-Christophe Carry, Fabienne Chatreaux, Stephanie Deprets, Olivier Duclos, Vincent Leroy, Sergio Mallart, Dominique Melon-Manguer, Maria Mendez-Perez, Fabrice Vergne
  • NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
    Publication number: 20190151330
    Abstract: The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 23, 2019
    Inventors: Jean-Christophe CARRY, Fabienne CHATREAUX, Stephanie DEPRETS, Olivier DUCLOS, Vincent LEROY, Sergio MALLART, Dominique MELON-MANGUER, Maria MENDEZ-PEREZ, Fabrice VERGNE
  • Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof
    Patent number: 10220044
    Abstract: The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: March 5, 2019
    Assignee: SANOFI
    Inventors: Jean-Christophe Carry, Fabienne Chatreaux, Stephanie Deprets, Olivier Duclos, Vincent Leroy, Sergio Mallart, Dominique Melon-Manguer, Maria Mendez-Perez, Fabrice Vergne
  • NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
    Publication number: 20170319594
    Abstract: The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Application
    Filed: July 26, 2017
    Publication date: November 9, 2017
    Inventors: Jean-Christophe CARRY, Fabienne CHATREAUX, Stephanie DEPRETS, Olivier DUCLOS, Vincent LEROY, Sergio MALLART, Dominique MELON-MANGUER, Maria MENDEZ-PEREZ, Fabrice VERGNE
  • NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
    Publication number: 20150352124
    Abstract: The present invention relates to therapeutic uses of the compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group.
    Type: Application
    Filed: July 8, 2015
    Publication date: December 10, 2015
    Inventors: Jean-Christophe CARRY, Fabienne CHATREAUX, Stephanie DEPRETS, Olivier DUCLOS, Vincent LEROY, Sergio MALLART, Dominique MELON-MANGUER, Maria MENDEZ-PEREZ, Fabrice VERGNE
  • Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof
    Patent number: 9115140
    Abstract: The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: August 25, 2015
    Assignee: SANOFI
    Inventors: Jean-Christophe Carry, Fabienne Chatreaux, Stephanie Deprets, Olivier Duclos, Vincent Leroy, Sergio Mallart, Dominique Melon-Manguer, Maria Mendez-Perez, Fabrice Vergne
  • NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
    Publication number: 20130261106
    Abstract: The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(R?)(R?)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.
    Type: Application
    Filed: April 2, 2013
    Publication date: October 3, 2013
    Applicant: SANOFI
    Inventors: Jean-Christophe CARRY, Fabienne CHATREAUX, Stephanie DEPRETS, Olivier DUCLOS, Vincent LEROY, Sergio MALLART, Dominique MELON-MANGUER, Maria MENDEZ-PEREZ, Fabrice VERGNE
  • Echinocandin derivatives, their method of preparation and their application as anti-fungal agents
    Patent number: 7285619
    Abstract: Compounds of the formula wherein the substituents are as defined in the application useful as antifungal agents.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: October 23, 2007
    Assignee: Aventis Pharma S.A.
    Inventors: Olivier Courtin, Patrick Fauveau, Astrid Markus, Dominique Melon Manguer, Jean-Marc Michel, Laurent Schio
  • Echinocandin derivatives, their method of preparation and their application as anti-fungal agents
    Patent number: 7160983
    Abstract: Compound of the formula wherein R2 is —CH2—CH2—NH2, R3 is —CH3, R4 is —OH, R is Z is methyl and salts thereof which are useful as antifungal agents.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: January 9, 2007
    Assignee: Aventis Pharma S.A.
    Inventors: Olivier Courtin, Patrick Fauveau, Astrid Markus, Dominique Melon Manguer, Jean-Marc Michel, Laurent Schio
  • Echinocandin derivatives, their method of preparation and their application as anti-fungal agents
    Publication number: 20050267019
    Abstract: Compounds of the formula wherein the substituents are as defined in the application useful as antifungal agents.
    Type: Application
    Filed: June 23, 2005
    Publication date: December 1, 2005
    Inventors: Oliver Courtin, Patrick Fauveau, Astrid Markus, Dominique Melon Manguer, Jean-Marc Michel, Laurent Schio
  • Fungicidal echinocandin derivatives and their preparation
    Patent number: 6864233
    Abstract: The invention concerns compounds of general formula (I) wherein: R1 represents a hydrogen atom, a hydroxy radical, Ob or Ncd; A represents an oxygen atom, a CH2 radical or a NH radical; B represents the radical of a steroid; R3 represents a hydrogen atom, a methyl or hydroxyl radical; R4 represents a hydrogen atom or a hydroxyl radical; T represents a hydrogen atom, a methyl radical, a CH1CONH2, CH2C?N radical, a (CH2)2NH2 or (CH2)2Nalk+X?radical; X being a halogen atom and alc an alkyl radical; Y represents a hydrogen atom, a hydroxyl radical or a halogen atom or a OSO3H radical; W represents a hydrogen atom or a OH radical; Z represents a hydrogen atom or a methyl radical. The compounds of formula (I) exhibit antifungal properties.
    Type: Grant
    Filed: February 14, 2001
    Date of Patent: March 8, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Olivier Courtin, Arlette Dussarat, Dominique Melon Manguer, Laurent Schio
  • Echinocandin derivatives, their method of preparation and their application as anti-fungal agents
    Publication number: 20040072737
    Abstract: Novel compounds of the formula 1
    Type: Application
    Filed: September 19, 2003
    Publication date: April 15, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Olivier Courtin, Patrick Fauveau, Astrid Markus, Dominique Melon Manguer, Jean-Marc Michel, Laurent Schio
  • Novel echinocandin derivatives, preparation method and use thereof as fungicides
    Publication number: 20040014602
    Abstract: The invention concerns compounds of general formula (I) wherein: R1 represents a hydrogen atom, a hydroxy radical, Ob or Ncd; A represents an oxygen atom, a CH2 radical or a NH radical; B represents the radical of a steroid; R3 represents a hydrogen atom, a methyl or hydroxyl radical; R4 represents a hydrogen atom or a hydroxyl radical; T represents a hydrogen atom, a methyl radical, a CH1CONH2, CH2C≡N radical, a (CH2),NH2 or (CH2)2Nalk+X− radical; X being a halogen atom and alc an alkyl radical; Y represents a hydrogen atom, a hydroxyl radical or a halogen atom or a OSO3H radical; W represents a hydrogen atom or a OH radical; Z represents a hydrogen atom or a methyl radical. The compounds of formula (I) exhibit antifungal properties.
    Type: Application
    Filed: December 3, 2002
    Publication date: January 22, 2004
    Inventors: Olivier Courtin, Arlette Dussarat, Dominique Melon Manguer, Laurent Schio
  • Echinocandin derivatives, preparation method and application as anti-fungal agents
    Patent number: 6677429
    Abstract: A compound of Formula I in which R1 and R2=H, OH, alkyl optionally substituted, or NR1 forms with the carbon bearing NR1R2 a double bond and R2 is Xra, X being O, NH or N-alkyl and Ra being H, alkyl optionally substituted; R=a chain containing up to 10 carbon atoms, optionally comprising one or several heteroatoms, one or several heterocycles; T=H, CH2, CH2CONH2, CH2C≡, (CH2)2NH2; Y=H, OH, halogen; W=H, OH; Z=H or CH3; said products have antifungal properties.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: January 13, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Olivier Courtin, Patrick Fauveau, Astrid Markus, Dominique Melon Manguer, Jean-Marc Michel, Laurent Schio