Abstract: An integrated module for extracorporeal blood treatment comprises a flat-shaped support element which exhibits on an internal face thereof a complex of fluid distribution lines and on an external face thereof a high-flow dialyzer. The support element comprises a base body (1) which exhibits fixture seatings (2), each of which houses an axially extended tract (38) of a fluid distribution line. The tract of line, with respect to adjacent tracts, has an increased diameter which is caused by a junction collar (39) made of a rigid material. Each fixture seating exhibits two axial locators (3a, 3b) for positioning the axial tract of line in a fixed position. The locators (3a, 3b) interact with the junction collar (39). The distribution lines are fixed to the base body (1) by a resilient fixture of the junction collars (39) in the seatings, with no necessity of gluing. The module is destined to be mounted on an apparatus for intensive treatment of renal insufficiency.

Abstract: The support element (4) is provided with a plurality of connectors (7), (8), (11) which receive corresponding counter-connectors of a blood treatment device. The support element is also predisposed to include a fluid distribution circuitry cooperating with the blood treatment device in order to provide an integrated module for blood treatment. An assembly process of the integrated module for blood treatment is also described.

Abstract: The invention relates to an integrated blood treatment module (1) comprising a support element (4) and a fluid distribution circuitry associated thereto; the distribution circuitry comprises at least a blood line (44), a portion of which is secured to the support element and defines with the latter at least a U-shaped tube length (44a) designed to cooperate, when in use, with a respective pump (3a). There are then further fluid lines (45, 48, 50, 51) fastened to the support element and defining each at least a U-shaped tube length (45a, 48a, 50a, 51a) with respect to said element and each designed to cooperate, when in use, with a respective pump (3b, 3c, 3d, 3e). The support element has a first zone (274) in which the portion of the blood line is secured, and at least a second zone (275) opposite said first zone, to which all the corresponding further tube lengths are fastened.

Abstract: The present invention relates to a multifunction device for treatment of blood and more particularly for extrarenal purification by extracorporeal circulation of blood. A device is proposed including a semipermeable separator component which is:a) active in adsorption and has at least one of the adsorption capacities belowa1: adsorption of TNF-.alpha. greater than or equal to approximately 600 nga2: adsorption of complement factor D greater than or equal to approximately 30 mga3: adsorption of interleukin 1-.beta. greater than or equal to approximately 300 ngb) has a urea clearance greater than or equal to approximately 20 ml/min for rates of blood flow, of dialysis liquid flow and of ultrafiltration equal respectively to approximately 100 ml/min, 33 ml/min and 0 ml/min.c) has an ultrafiltration coefficent in the presence of blood greater than approximately 5 ml/(h.mmHg).d) the volume of compartment in the device intended for circulation of blood is less than or equal to approximately 150 ml.