Patents by Inventor Dominique Verhelle

Dominique Verhelle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EZH2 inhibitor combination therapies
    Patent number: 11529344
    Abstract: This invention relates to combination therapies comprising an EZH2 inhibitor and a chemotherapeutic agent, and associated pharmaceutical compositions, methods of treatment, and pharmaceutical uses.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: December 20, 2022
    Assignee: Pfizer Inc.
    Inventors: Manfred Kraus, Pei-Pei Kung, Thomas Andrew Paul, Shikhar Sharma, Dominique Verhelle
  • EZH2 INHIBITOR COMBINATION THERAPIES
    Publication number: 20200268740
    Abstract: This invention relates to combination therapies comprising an EZH2 inhibitor and a chemotherapeutic agent, and associated pharmaceutical compositions, methods of treatment, and pharmaceutical uses.
    Type: Application
    Filed: November 9, 2018
    Publication date: August 27, 2020
    Applicant: Pfizer Inc.
    Inventors: Manfred Kraus, Pei-Pei Kung, Thomas Andrew Paul, Shikhar Sharma, Dominique Verhelle
  • Methods and compositions using immunomodulatory compounds in combination therapy
    Publication number: 20080051431
    Abstract: Provided herein are compositions comprising one or more immunomodulatory compounds and valproic acid, hydroxyurea or trichostatin A, methods for their use in CD34+ hematopoietic stem cell expansion in vitro and in vivo for bone marrow reconstitution and bone marrow transplantation, increasing fetal hemoglobin expression, and methods for treating, preventing and/or managing cancer, tumors and hematological diseases and disorders.
    Type: Application
    Filed: May 24, 2007
    Publication date: February 28, 2008
    Inventors: Dominique Verhelle, Kyle Chan, Laura Corral, Laure Moutouh de Parseval, Helen Brady
  • Methods and compositions using immunomodulatory compounds for the treatment of disorders associated with low plasma leptin levels
    Publication number: 20070066512
    Abstract: Methods of treating, preventing and/or managing disorders associated with low plasma leptin levels are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active agent.
    Type: Application
    Filed: September 11, 2006
    Publication date: March 22, 2007
    Inventors: Dominique Verhelle, Kyle Chan, Helen Brady