Patents by Inventor Domnic Martyres
Domnic Martyres has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8153660Abstract: One object of the present invention are novel substituted piperidyl-propane-thiols of the formula (1), wherein R1, R2, R3 and R4 are defined as below. Another object of the present invention is to provide agonists or antagonists of CCR-3, or pharmaceutically acceptable salts thereof, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.Type: GrantFiled: October 25, 2007Date of Patent: April 10, 2012Assignee: Boehringer Ingelheim International GmbHInventors: Domnic Martyres, Matthias Hoffmann, Peter Seither, Thierry Bouyssou
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Patent number: 8148403Abstract: One object of the present invention are novel substituted piperidyl-propane-thiols of the formula (1), wherein R1, R2, R3 and D are defined as below. Another object of the present invention is to provide agonists or antagonists of CCR-3, or pharmaceutically acceptable salts thereof, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.Type: GrantFiled: October 25, 2007Date of Patent: April 3, 2012Assignee: Boehringer Ingelheim International GmbHInventors: Domnic Martyres, Matthias Hoffmann, Peter Seither, Thierry Bouyssou
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Publication number: 20120028938Abstract: The present invention relates to pyrazole compounds of formula (I) and pharmaceutically acceptable salts thereof having CRTH2-activity, wherein W, L1, L2, X, L3, Y, R1 and R2 are as defined in the specification and claims, to their use as medicaments and to pharmaceutical formulations, containing said compounds or containing a combination of said compounds with one or more active substances.Type: ApplicationFiled: January 24, 2011Publication date: February 2, 2012Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Thorsten OOST, Ralf ANDERSKEWITZ, Dieter Wolfgang HAMPRECHT, Christoph HOENKE, Domnic MARTYRES, Wolfgang RIST, Peter SEITHER
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Publication number: 20110021501Abstract: The invention relates to new piperidino-dihydrothienopyrimidines of formula 1, as well as pharmacologically acceptable salts thereof, wherein X is SO or SO2, but preferably SO, and wherein R1, R2, R3 and R4 may have the meanings given in claim 1, as well as pharmaceutical compositions which contain these compounds. These new piperidino-dihydrothienopyrimidines are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers.Type: ApplicationFiled: October 16, 2008Publication date: January 27, 2011Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Pascale Pouzet, Ralf Anderskewitz, Horst Dollinger, Dennis Fiegen, Thomas Fox, Rolf Goeggel, Christoph Hoenke, Domnic Martyres, Peter Nickolaus, Klaus Klinder
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Publication number: 20100317634Abstract: One object of the present invention are novel substituted piperidyl-propane-thiols of the formula (1), wherein R1, R2, R3 and R4 are defined as below. Another object of the present invention is to provide agonists or antagonists of CCR-3, or pharmaceutically acceptable salts thereof, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: October 25, 2007Publication date: December 16, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Domnic Martyres, Matthias Hoffmann, Peter Seither, Thierry Bouyssou
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Publication number: 20100317669Abstract: One object of the present invention are novel substituted piperidyl-propane-thiols of the formula (1), wherein R1, R2, R3 and D are defined as below. Another object of the present invention is to provide agonists or antagonists of CCR-3, or pharmaceutically acceptable salts thereof, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: October 25, 2007Publication date: December 16, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Domnic Martyres, Matthias Hoffmann, Peter Seither, Thierry Bouyssou
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Publication number: 20100305102Abstract: The invention relates to new dihydrothienopyrimidinesulphoxides of formula 1, as well as pharmacologically acceptable salts thereof, wherein X is SO or SO2, but preferably SO, and wherein R3 denotes an optionally substituted, mono- or bicyclic, unsaturated, partially saturated or saturated heterocycle or an optionally substituted, mono- or bicyclic heteroaryl and wherein R1 and R2 have the meanings stated in claim 1, as well as pharmaceutical compositions which contain these compounds. These new dihydrothienopyrimidinesulphoxides are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers.Type: ApplicationFiled: October 16, 2008Publication date: December 2, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Pascale Pouzet, Ralf Anderskewitz, Horst Dollinger, Dennis Fiegen, Thomas Fox, Rolf Goeggel, Christoph Hoenke, Domnic Martyres, Peter Nickolaus, Klaus Klinder
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Publication number: 20100261687Abstract: Object of the present invention are novel substituted compounds of the formula 1, wherein A, R1, R2, R3 and R4 are defined as in the description. Another object of the present invention is to provide antagonists of CCR3, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: March 19, 2010Publication date: October 14, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Marc GRUNDL, Horst DOLLINGER, Riccardo GIOVANNINI, Christoph HOENKE, Matthias HOFFMANN, Jan KRIEGL, Domnic MARTYRES, Georg RAST, Peter SEITHER
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Publication number: 20100234347Abstract: The invention relates to novel pteridines of formula (1), suitable for the treatment of airway or gastrointestinal complaints or diseases, inflammatory diseases of the joints, the skin or eyes, diseases of the peripheral or central nervous systems or cancerous diseases and pharmaceutical compositions comprising said compounds.Type: ApplicationFiled: May 15, 2007Publication date: September 16, 2010Applicant: Boehringer Ingelheim Internationl GmbHInventors: Horst Dollinger, Domnic Martyres, Rolf Goeggel, Birgit Jung, Peter Nickolaus
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Publication number: 20100197656Abstract: Dihydrothienopyrimidines of formula 1 and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.Type: ApplicationFiled: April 2, 2010Publication date: August 5, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Christoph HOENKE, Birgit JUNG, Domnic MARTYRES, Peter NICKOLAUS, Pascale POUZET
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Patent number: 7759365Abstract: Disclosed are novel piperidine-substituted indoles- or heteroderivatives thereof of the formula 1: wherein R1, R5, R6, R7, A, B, D-E, Y, i, j, n and m are defined as below. The compounds of formula 1 are useful as agonists or antagonists of CCR-3. The present invention is also directed to pharmaceutically acceptable salts thereof, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.Type: GrantFiled: April 26, 2006Date of Patent: July 20, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Domnic Martyres, Pascale Pouzet, Christoph Hoenke, Peter Seither, Silke Hobbie, Thierry Bouyssou
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Patent number: 7750009Abstract: The invention relates to new pteridines which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.Type: GrantFiled: November 18, 2005Date of Patent: July 6, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Horst Dollinger, Juergen Mack, Domnic Martyres, Birgit Jung, Peter Nickolaus
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Patent number: 7723341Abstract: Dihydrothienopyrimidines of formula 1 and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.Type: GrantFiled: February 19, 2009Date of Patent: May 25, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Christoph Hoenke, Birgit Jung, Domnic Martyres, Peter Nickolaus, Pascale Pouzet
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Patent number: 7723360Abstract: A compound of general formula 1a wherein R1, R5, R6, A, B, Y, i, j and m are defined as in the description and claims. It is another object of the present invention to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.Type: GrantFiled: July 28, 2005Date of Patent: May 25, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Ralf Anderskewitz, Domnic Martyres, Franz Birke, Thierry Bouyssou
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Patent number: 7718654Abstract: The invention relates to new pteridine compounds of formula 1 wherein R1, R2 , R3 and R4 have the meanings given herein, which are useful for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system, or cancers. The invention further relates to pharmaceutical compositions which contain these compounds.Type: GrantFiled: November 18, 2005Date of Patent: May 18, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Domnic Martyres, Horst Dollinger, Birgit Jung, Peter Nickolaus
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Publication number: 20100120766Abstract: The invention relates to new pteridines which are suitable for treating respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system and cancers. This invention also relates to pharmaceutical compositions containing these compounds.Type: ApplicationFiled: January 19, 2010Publication date: May 13, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Horst DOLLINGER, Domnic MARTYRES, Juergen MACK, Rolf GOEGGEL, Birgit JUNG, Peter NICKOLAUS
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Patent number: 7674788Abstract: The invention relates to new pteridines which are suitable for treating respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system and cancers. This invention also relates to pharmaceutical compositions containing these compounds.Type: GrantFiled: May 22, 2007Date of Patent: March 9, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Horst Dollinger, Domnic Martyres, Juergen Mack, Rolf Goeggel, Birgit Jung, Peter Nickolaus
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Patent number: 7648988Abstract: Described are new pteridine compounds of the formula 1, where the variables are as described herein. The compounds are useful for the treatment of: respiratory or gastrointestinal complaints or diseases; inflammatory diseases of the joints, skin or eyes; diseases of the peripheral or central nervous system; and cancers. Also described are pharmaceutical compositions which contain these compounds.Type: GrantFiled: February 14, 2008Date of Patent: January 19, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Horst Dollinger, Domnic Martyres, Juergen Mack, Peter Nickolaus, Birgit Jung
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Publication number: 20090186875Abstract: Dihydrothienopyrimidines of formula 1 and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.Type: ApplicationFiled: February 19, 2009Publication date: July 23, 2009Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Christoph HOENKE, Birgit JUNG, Domnic MARTYRES, Peter NICKOLAUS, Pascale POUZET
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Patent number: 7550472Abstract: The invention relates to new pteridines which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.Type: GrantFiled: November 18, 2005Date of Patent: June 23, 2009Assignee: Boehringer Ingelheim International GmbHInventors: Horst Dollinger, Juergen Mack, Domnic Martyres, Birgit Jung, Peter Nickolaus