Patents by Inventor Don Axworthy

Don Axworthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for reducing non-target retention of immunoconjugates and metabolites thereof
    Patent number: 5648059
    Abstract: Methods for reducing non-target retention of active moieties associated with immunoconjugates and their metabolites, and more specifically, for reducing renal retention of such active moieties, are disclosed. Methods of the present invention comprise administering an effective amount of a non-target reduction moiety, such as lysine, in addition to a therapeutically or diagnostically effective amount of an immunoconjugate. The non-target reduction moiety localizes in the kidneys and inhibits renal retention and reabsorption of active moieties associated with immunoconjugates and their metabolites.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: July 15, 1997
    Assignee: NeoRx Corporation
    Inventors: Mary Ann Gray, Don Axworthy, David Wilkening
  • Methods for reducing non-target retention of immunoconjugates and metabolites thereof
    Patent number: 5380513
    Abstract: Methods for reducing non-target retention of active moieties associated with immunoconjugates and their metabolites, and more specifically, for reducing renal retention of such active moieties, are disclosed. Methods of the present invention comprise administering an effective amount of a non-target reduction moiety, such as lysine, in addition to a therapeutically or diagnostically effective amount of an immunoconjugate. The non-target reduction moiety localizes in the kidneys and inhibits renal retention and reabsorption of active moieties associated with immunoconjugates and their metabolites.
    Type: Grant
    Filed: August 21, 1992
    Date of Patent: January 10, 1995
    Assignee: NeoRx Corporation
    Inventors: Mary A. Gray, Don Axworthy, David Wilkening