Abstract: The disclosure provides processes for synthesizing Compound I, and pharmaceutically acceptable salts thereof.

Abstract: A device and method for disclosing position of a positionable input by positioning the input over a range of positions to cause the magnitude of the directional component of a vector representing a field or force produced by a source to change from a reference magnitude or reference direction as the input is being positioned while an electric circuit that contains a sensor for sensing the directional component is changing the value of an electric signal for restoring the magnitude of the directional component being sensed by the sensor to the reference magnitude or reference direction, and using the value of the electric signal to disclose the position of the input.

Abstract: A device and method for disclosing position of a positionable input by positioning the input over a range of positions to cause the magnitude of the directional component of a vector representing a field or force produced by a source to change from a reference magnitude or reference direction as the input is being positioned while an electric circuit that contains a sensor for sensing the directional component is changing the value of an electric signal for restoring the magnitude of the directional component being sensed by the sensor to the reference magnitude or reference direction, and using the value of the electric signal to disclose the position of the input.

Abstract: A filling apparatus and method including a carrier for transporting containers and having a plurality of valves, each of the valves being opened for an individual, specific period of time to control a flow of liquid into the respective containers, while the containers are transported by the carrier. An exit feed path transports the containers after the containers have been filled, and a sensor, such as a camera, detects a level of liquid in the respective containers, while the containers are on the exit feed path. The sensor produces a signal that is stored as data representing the level of liquid for the individual containers. The data is then tracked and used for valve optimization. A period of time that each individual valve is opened for subsequent fillings is adjusted based on the signal and the historical performance of each valve.

Abstract: A laser diode based system for direct injection of selected thermal-infrared (IR) wavelength radiation or energy into articles for a wide range of processing purposes is provided. These purposes may include heating, raising or maintaining the temperature of articles, or stimulating a target item in a wide range of different industrial, medical, consumer, or commercial applications. The system is especially applicable to operations that require or benefit from the ability to irradiate at specifically selected wavelengths or to pulse or inject the radiation. The system is particularly advantageous when functioning at higher speeds and in a non-contact environment with the target.

Abstract: A system for direct injection of selected thermal-infrared (IR) wavelength radiation or energy into articles for a wide range of processing purposes is provided. These purposes may include heating, raising or maintaining the temperature of articles, or stimulating a target item in a range of different industrial, medical, consumer, or commercial circumstances. The system is especially applicable to operations that require or benefit from the ability to irradiate at specifically selected wavelengths or to pulse or inject the radiation. The system is particularly advantageous when functioning at higher speeds and in a non-contact environment with the target.

Abstract: This application relates to an apparatus and method for providing snapshot action thermal infrared imaging within automated process control article inspection applications. More specifically, it pertains to the use of snapshot mode lead salt area-array imaging sensors (20) as the imaging front-end in high-speed machine vision inspection systems (12). the relatively low-cost, good measurement sensitivity at temperatures consistent with thermo-electric cooling means, and the ability to be operated in snapshot mode enables lead salt-based image acquisition sensors (20) to be used in a variety of automated process control and article inspection applications.

Abstract: A system for direct injection of selected thermal-infrared (IR) wavelength radiation or energy into articles for a wide range of processing purposes is provided. These purposes may include heating, raising or maintaining the temperature of articles, or stimulating a target item in a range of different industrial, medical, consumer, or commercial circumstances. The system is especially applicable to operations that require or benefit from the ability to irradiate at specifically selected wavelengths or to pulse or inject the radiation. The system is particularly advantageous when functioning at higher speeds and in a non-contact environment with the target.

Abstract: This application relates to an apparatus and method for providing patterned illumination fields for use within process control and article inspection applications. More specifically, it pertains to the use of patterned illuminators to enable visual surface inspection of polished objects such as ball bearings. The use of patterned illuminators properly disposed in relation to a polished part under inspection allows small surface imperfections such as scratches and pits to become visible against the normal surface background. The use of carefully engineered illuminators facilitates advantageous defect-site scattering from generally dark field sources. The patterned nature of the illuminators defined by this invention allows the complete surface of three-dimensional parts to be effectively highlighted using dark field illumination fields.

Abstract: This application relates to an apparatus and method for automated inspection of formed metal containers. More specifically, it pertains to the use of machine vision systems to identify and correlate manufacturing defects occurring in formed food and beverage containers to specific manufacturing paths or sources of origin (eg., body makers) used in the container forming process. The disclosed invention is enabled by the placement of a machine-readable code on specific portions of the can body during the forming process and the use of illumination exposure techniques.

Abstract: The invention provides for a graphical user interface which provides for very simple and intuitive ways of changing single or multiple inspection parameters. The graphical display immediately shows what the monitoring or inspection result would have been if the effected change had been in place during the inspection of the last “N” parts. This retrospective graphical “look-back” invokes immediate re-inspection facilitating an estimation of what the future inspection or process monitoring results will be if future production looks similar to the recent past production. The re-inspection results are immediately shown with a combination of visualization for ease of understanding and settings optimization. The visualization also shows selected other associated data to each specific inspection for ease of tracking and optimizing production processes.

Abstract: This application relates to an apparatus and method for automated inspection of formed metal containers. More specifically, it pertains to the use of machine vision systems to identify and correlate manufacturing defects occurring in formed food and beverage containers to specific manufacturing paths or sources of origin (e.g., body makers) used in the container forming process. The disclosed invention is enabled by the placement of a machine-readable code on specific portions of the can body during the forming process and the use of machine vision reading techniques.

Abstract: This invention relates to a method and apparatus for handling parts ejected from an injection molding machine (10). More particularly, in one aspect, the invention is directed to a system (20) whereby data molded into the ejected part is used to provide useful feedback for the molding process. In another aspect, molded parts formed in a multiple molding die (12) are ejected from the die in a manner to maintain the relative sequential or matrix organization so that useful feedback information can be generated. This system is particularly useful with subsequent machine vision and inspection applications.

Abstract: A stretch blow molding system that condition preforms such that the temperature distribution within the cross-section of each preform is optimized prior to blow molding operations is provided. The system has a temperature measurement and control system capable of directly monitoring both the outside as well as inside surface temperature of preforms at different stages of transport throughout the thermal conditioning section of the system.

Abstract: This invention relates to a method and apparatus for mass and/or volume measurements of manufactured articles. More particularly, this invention relates to a method and apparatus for mass and/or volume measurements that can be performed on-line in a part manufacturing process. On-line measurement of the mass or volume of material contained in a specific region of interest of the manufactured items is performed 100% on-line. Real-time process control information is based on real-time measurement of the mass or volume of material contained in a specific region of interest of a manufactured item. Automated quality control inspection for manufactured articles is based on real-time measurement of the mass or volume of material contained in a specific region of interest of manufactured items.