Patents by Inventor Don DeVoe

Don DeVoe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Two-dimensional microfluidics for protein separations and gene analysis
    Patent number: 7641780
    Abstract: The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array of second dimension microchannels extending in a second direction, preferably, orthogonal to the first dimension. The ends of at least some of the microchannels are in fluid communication with a plurality of reservoirs. The substrates may further include a number of microchannels and reservoirs. The reservoirs are in electrical communication with a plurality of electrodes and voltage power sources. The device enables two dimensional separations of proteins, DNA and other biomolecules. According to another aspect of the invention, an array of tertiary microchannels extending in a third direction may be utilized.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: January 5, 2010
    Assignees: Calibrant Biosystems, Inc., The University of Maryland
    Inventors: Cheng Sheng Lee, Don DeVoe
  • Microfluidic apparatus for performing gel protein extractions and methods for using the apparatus
    Patent number: 7070682
    Abstract: The invention relates to an apparatus for performing gel protein extractions and methods of using the apparatus.
    Type: Grant
    Filed: January 15, 2002
    Date of Patent: July 4, 2006
    Inventors: Cheng Lee, Don DeVoe
  • Two-dimensional microfluidics for protein separations and gene analysis
    Publication number: 20060054504
    Abstract: The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array of second dimension microchannels extending in a second direction, preferably, orthogonal to the first dimension. The ends of at least some of the microchannels are in fluid communication with a plurality of reservoirs. The substrates may further include a number of microchannels and reservoirs. The reservoirs are in electrical communication with a plurality of electrodes and voltage power sources. The device enables two dimensional separations of proteins, DNA and other biomolecules. According to another aspect of the invention, an array of tertiary microchannels extending in a third direction may be utilized.
    Type: Application
    Filed: March 23, 2005
    Publication date: March 16, 2006
    Inventors: Cheng Lee, Don DeVoe
  • Plastic microfluidics enabling two-dimensional protein separations in proteome analysis
    Patent number: 6974526
    Abstract: The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array of second dimension microchannels extending in a second direction, preferably, orthogonal to the first dimension. The ends of at least some of the microchannels are in fluid communication with a plurality of reservoirs. The substrates may further include a number of microchannels and reservoirs. The reservoirs are in electrical communication with a plurality of electrodes and voltage power sources. The device enables two dimensional separations of proteins and other biomolecules. According to another aspect of the invention, an isoelectric point based separation is enabled in a first dimension, and a size based separation in a second dimension.
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: December 13, 2005
    Assignees: Calibrant Biosystems, Inc., The University of Maryland
    Inventors: Cheng Sheng Lee, Don DeVoe
  • Plastic microfluidics enabling two-dimensional protein separations in proteome analysis
    Publication number: 20020170825
    Abstract: The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array of second dimension microchannels extending in a second direction, preferably, orthogonal to the first dimension. The ends of at least some of the microchannels are in fluid communication with a plurality of reservoirs. The substrates may further include a number of microchannels and reservoirs. The reservoirs are in electrical communication with a plurality of electrodes and voltage power sources. The device enables two dimensional separations of proteins and other biomolecules. According to another aspect of the invention, an isoelectric point based separation is enabled in a first dimension, and a size based separation in a second dimension.
    Type: Application
    Filed: May 1, 2002
    Publication date: November 21, 2002
    Inventors: Cheng Sheng Lee, Don DeVoe
  • Microfluidic apparatus for performing gel protein extractions and methods for using the apparatus
    Publication number: 20020121444
    Abstract: The invention relates to an apparatus for performing gel protein extractions and methods of using the apparatus.
    Type: Application
    Filed: January 15, 2002
    Publication date: September 5, 2002
    Inventors: Cheng Lee, Don DeVoe