Abstract: A packaging system includes a packaging container, an absorbent pad, a protective wrap, an insulator, and a shipping container. The packaging container includes a vessel and a lid which attach securely together through a plurality of locking tabs and tab receptacles to form an air tight seal. The protective wrap surrounds the medical substance during shipment and limits the movement of the medical substance within the vessel. The medical substance is stored inside the vessel on the absorbent pad, the vessel is positioned within the insulator, and the insulator is placed within the shipping container.