Abstract: Controllers for implantable medical devices, and associated methods are disclosed. A device in accordance with one embodiment includes a hand-held housing, an image display device carried by the housing, and an input device carried by the housing. In particular embodiments, one portion of the housing can be rotatable relative to the other, or at a fixed, non-zero angle relative to the other, with the image display device and the input device carried by one portion and a wireless communication device carried by the other portion. A controller can be operatively coupled to the image display device to control the orientation of an image (e.g., whether the image is upright or inverted), presented at the display device in response to a signal received from the input device. The image can include a user-selectable icon, e.g., for controlling parameters associated with delivering therapeutic electromagnetic signals to a patient.