Patents by Inventor Don P. Wolf

Don P. Wolf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRIMATE TOTIPOTENT AND PLURIPOTENT STEM CELLS PRODUCED BY SOMATIC CELL NUCLEAR TRANSFER
    Publication number: 20110244450
    Abstract: Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced from these stem cells. The stem cells are produced from an enucleated host cell from a first donor and nuclear genetic material from a somatic cell of a second donor. Methods for making and using such compositions of such stem cells are also provided.
    Type: Application
    Filed: May 31, 2011
    Publication date: October 6, 2011
    Inventors: Shoukhrat M. Mitalipov, Don P. Wolf, James Byrne
  • Primate pluripotent stem cells produced by somatic cell nuclear transfer
    Patent number: 7972849
    Abstract: Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced from these stem cells. The stem cells are produced from an enucleated host cell from a first donor and nuclear genetic material from a somatic cell of a second donor. Methods for making and using such compositions of such stem cells are also provided.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: July 5, 2011
    Assignee: Oregon Health & Science University
    Inventors: Shoukhrat M. Mitalipov, Don P. Wolf, James Byrne
  • PRIMATE TOTIPOTENT AND PLURIPOTENT STEM CELLS PRODUCED BY SOMATIC CELL NUCLEAR TRANSFER
    Publication number: 20090004740
    Abstract: Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced from these stem cells. The stem cells are produced from an enucleated host cell from a first donor and nuclear genetic material from a somatic cell of a second donor. Methods for making and using such compositions of such stem cells are also provided.
    Type: Application
    Filed: May 16, 2008
    Publication date: January 1, 2009
    Inventors: Shoukhrat M. Mitalipov, Don P. Wolf, James Byrne
  • Enhancement of fertilization capability of oocytes
    Patent number: 5693534
    Abstract: A method is provided for increasing the fertilization potential of oocytes comprising culturing oocytes in vitro with an effective amount of inhibin, activin, or a combination of inhibin and activin. Preferably the oocytes being cultured are immature. After the culturing step, the oocytes can be fertilized. The oocytes are suitably cryopreserved and thawed before the culturing step.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 2, 1997
    Assignees: Genentech, Inc., Oregon Regional Primate Research Center
    Inventors: Baha M. Alak, Richard L. Stouffer, Don P. Wolf, Teresa K. Woodruff
  • Use of human inhibin and human activin to increase the number of mature primate oocytes
    Patent number: 5563059
    Abstract: A method is provided for increasing the fertilization potential of oocytes comprising culturing oocytes in vitro with an effective amount of inhibin, activin, or a combination of inhibin and activin. Preferably the oocytes being cultured are immature. After the culturing step, the oocytes can be fertilized. The oocytes are suitably cryopreserved and thawed before the culturing step.
    Type: Grant
    Filed: February 23, 1993
    Date of Patent: October 8, 1996
    Assignees: Genentech, Inc., Medical Research Foundation of Oregon
    Inventors: Baha M. Alak, Richard L. Stouffer, Don P. Wolf, Teresa K. Woodruff