Patents by Inventor Don Purschke
Don Purschke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6218373Abstract: A method of treating a disease of condition administering topically to the skin or exposed tissue of a human, a dosage amount of a pharmaceutical composition, said dosage comprising a therapeutically effective amount of a drug to treat said disease or condition and a form of hyaluronic acid characterized in that the composition is immediately available to transport the drug percutaneously into the epidermis of the skin or exposed tissue to the site of trauma or pathology of the disease or condition to be treated.Type: GrantFiled: June 6, 1995Date of Patent: April 17, 2001Assignee: Hyal Pharmaceutical CorporationInventors: Rudolf Edger Falk, Samuel Simon Asculai, David Hochman, Don Purschke, Ehud Shmuel Klein, David William Harper
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Patent number: 6147059Abstract: Pharmaceutical compositions from which effective non-toxic (to the patient) dosage amounts may be taken and applied to the skin and/or exposed tissue of a human, each effective dosage amount comprising pharmaceutical excipients suitable for topical application, an effective non-toxic dosage amount of a drug to treat and to assist to resolve a disease and/or condition of the skin and/or exposed tissue or a human and an effective non-toxic dosage amount of hyaluronic acid and/or salts thereof and/or homologues, analogues, derivatives, complexes, esters, fragments, and/or sub-units or hyaluronic acid sufficient to transport (to facilitate or cause the transport of) the drug, to a site in the skin including epidermis or exposed tissue or a disease or condition for percutaneous transport into the skin and/or exposed tissue to accumulate and remain there for a prolonged period of time and which is systemic independent acting.Type: GrantFiled: June 6, 1995Date of Patent: November 14, 2000Assignee: Hyal Pharmaceutical CorporationInventors: Rudolf E Falk, Samuel S Asculai, Ehud S Klein, David W Harper, David Hochman, Don Purschke
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Patent number: 6140312Abstract: The invention relates to a method of rapidly transporting a drug to the epidermis and accumulating and maintaining the drug therein for a prolonged period of time comprising administration of a therapeutically efective non-toxic amount of the drug with an effective amount of hyaluronic acid.Type: GrantFiled: June 6, 1995Date of Patent: October 31, 2000Assignee: Hyal Pharmaceutical CorporationInventors: Rudolf Edger Falk, Samuel Simon Asculai, David Hochman, Don Purschke, Ehud Shmuel Klein, David William Harper
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Patent number: 6136793Abstract: A method of treating a disease or condition comprising administering topically to the skin or exposed tissue of a human, a dosage amount of a pharmaceutical composition, said dosage comprising a therapeutically effective amount of a drug to treat said disease or condition and a form of hyaluronic acid characterized in that the composition is immediately available to transport the drug percutaneously into the epidermis of the skin or exposed tissue to the site of trauma or pathology of the disease or condition to be treated.Type: GrantFiled: June 6, 1995Date of Patent: October 24, 2000Assignee: Hyal Pharmaceutical CorporationInventors: Rudolf Edger Falk, Samuel Simon Asculai, David Hochman, Don Purschke, Ehud Shmuel Klein, David William Harper
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Patent number: 6114314Abstract: Topically applied transdermally quick penetrating (best targeting the epidermis and subsequently remaining there for a prolonged period of time) systemic independent acting, combinations and formulations which employ, combine, or incorporate a therapeutically effective non-toxic (to the patient) amount of a drug which inhibits prostaglandin synthesis together with an amount of hyaluronic acid and/or salts thereof (for example the sodium salt) and/or homologues, analogues, derivatives, complexes, esters, fragments, and/or sub units of hyaluronic acid to treat a disease and condition of the skin and exposed tissue for example, basal cell carcinoma, the precancerous, often recurrent, actinic keratoses lesions, fungal lesions, "liver" spots and like lesions (found for the most part in the epidermis), squamous cell tumours, metastatic cancer of the breast to the skin, primary and metastatic melanoma in the skin, genital warts cervical cancer, and HPV (Human Papilloma Virus) including HPV of the cervix, psoriasis (Type: GrantFiled: December 1, 1994Date of Patent: September 5, 2000Assignee: Hyal Pharmaceutical Corp.Inventors: Rudolf Edgar Falk, Samuel Simon Asculai, Ehud Shmuel Klein, David W. Harper, David Hochman, Don Purschke
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Patent number: 6103704Abstract: A method of accumulating a drug and a form of hyaluronic acid in the skin and/or exposed tissue of a human includes topically administering a therapeutically effective dosage amount of a formulation which comprises at least 5 mg/cm.sup.2 of the form of hyaluronic acid and a therapeutically effective amount of the drug.Type: GrantFiled: February 17, 1993Date of Patent: August 15, 2000Assignee: Hyal Pharmaceutical CorporationInventors: Rudolf Edgar Falk, Samuel Simon Asculai, Ehud Shmuel Klein, David William Harper, David Hochman, Don Purschke
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Patent number: 6087344Abstract: Pharmaceutical compositions from which effective non-toxic (to the patient) dosage amounts may be taken and applied to the skin and/or exposed tissue of a human, each effective dosage amount comprising pharmaceutical excipients suitable for topical application, an effective non-toxic dosage amount of a drug to treat and to assist to resolve a disease and/or condition of the skin and/or exposed tissue of a human and an effective non-toxic dosage amount of hyaluronic acid and/or salts thereof and/or homologues, analogues, derivatives, complexes, esters, fragments, and/or sub-units of hyaluronic acid sufficient to transport (to facilitate or cause the transport of) the drug, to a site in the skin including epidermis or exposed tissue of a disease or condition for percutaneous transport into the skin and/or exposed tissue to accumulate and remain there for a prolonged period of time and which is systemic independent acting.Type: GrantFiled: June 7, 1995Date of Patent: July 11, 2000Assignee: Hyal Pharmaceutical CorporationInventors: Rudolf E Falk, Samuel S Asculai, Ehud S Klein, David W Harper, David Hochman, Don Purschke
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Patent number: 5990096Abstract: The invention relates to a method of controlling the unloading of a drug from the skin or exposed tissue of a human into the lymphatic system comprising transporting an effective dosage amount of the drug into the skin or exposed tissue by an effective non-toxic amount of a form of hyaluronic acid.Type: GrantFiled: June 6, 1995Date of Patent: November 23, 1999Assignee: Hyal Pharmaceutical CorporationInventors: Samuel Simon Asculai, David Hochman, Don Purschke, David William Harper, Ehud Shmuel Klein, Rudolf Edger Falk
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Patent number: 5977088Abstract: Pharmaceutical compositions from which effective non-toxic (to the patient) dosage amounts may be taken and applied to the skin and/or exposed tissue of a human, each effective dosage amount comprising pharmaceutical excipients suitable for topical application, an effective non-toxic dosage amount of a drug to treat and to assist to resolve a disease and/or condition of the skin and/or exposed tissue of a human and an effective non-toxic dosage amount of hyaluronic acid and/or salts thereof and/or homologues, analogues, derivatives, complexes, esters, fragments, and/or sub-units of hyaluronic acid sufficient to transport (to facilitate or cause the transport of) the drug, to a site in the skin including epidermis or exposed tissue of a disease or condition for percutaneous transport into the skin and/or exposed tissue to accumulate and remain there for a prolonged period of time and which is systemic independent acting.Type: GrantFiled: June 6, 1995Date of Patent: November 2, 1999Assignee: Hyal Pharmaceutical CorporationInventors: David William Harper, Ehud Shmuel Klein, Rudolf Edger Falk, Samuel Simon Asculai, David Hochman, Don Purschke
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Patent number: 5942498Abstract: Topically applied transdermally quick penetrating compositions containing a drug and hyaluronic acid and/or salts thereof and methods of treating diseases and conditions employing said compositions.Type: GrantFiled: June 6, 1995Date of Patent: August 24, 1999Assignee: Hyal Pharmaceutical CorporationInventors: Rudolf Edger Falk, Samuel Simon Asculai, Ehud Shmuel Klein, David William Harper, David Hochman, Don Purschke