Patents by Inventor Don Wendell
Don Wendell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6508938Abstract: A multiple channel high throughput purification system for purifying a plurality of samples, preferably four or more samples from a chemical library. The high throughput purification uses chromatography, and more preferably, super critical fluid chromatography. Four parallel channels are provided in this system and coupled to a common analyzer and computer. The four channels direct the selected sample flow through a separator, such as an SFC column, a detector, such as a UV detector, to detect peaks within the sample flow, and a micro sample valve that splits a sampling of the flow to an analyzer, such as a mass spectrometer. The system also utilizes unique back pressure regulator assemblies and pressure relief assemblies to maintain a selected pressure within the purification channel. While the sample flow continues, the mass spectrometer simultaneously analyzes the sampling to determine if a target compound is within the sample portion.Type: GrantFiled: April 2, 2001Date of Patent: January 21, 2003Assignee: Ontogen CorporationInventors: Romaine Maiefski, Don Wendell, William C. Ripka, Jonathan D. Krakover
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Patent number: 6416718Abstract: A wash station assembly and method for washing selected samples in a sample containing assembly. The wash station assembly includes a wash station having a frame and a fluid dispensing assembly connected to the frame. The fluid dispensing assembly has a selector valve that is connectable to a plurality of fluid lines and is adjustable to allow only one of the fluids to pass through the selector valve at a time. An array of syringes is coupled to the selector valve and positioned to receive the fluid passing through the selector valve. Each syringe includes a check valve that prevents backflow of fluid or air into the syringe through the pipetting needles. A distribution manifold is connected to the selector valve and receives the fluid passing through the selector valve. The manifold has a plurality of distribution channels coupled to the syringes, to direct the fluid into the syringes. Each distribution channel has a manifold valve therein that prevents backflow of fluid into the manifold from the syringes.Type: GrantFiled: June 16, 1999Date of Patent: July 9, 2002Assignee: Ontogen CorporationInventors: Romaine Maiefski, Don Wendell
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Publication number: 20020059945Abstract: A wash station assembly and method for washing selected samples in a sample containing assembly. The wash station assembly includes a wash station having a frame and a fluid dispensing assembly connected to the frame. The fluid dispensing assembly has a selector valve that is connectable to a plurality of fluid lines and is adjustable to allow only one of the fluids to pass through the selector valve at a time. An array of syringes is coupled to the selector valve and positioned to receive the fluid passing through the selector valve. Each syringe includes a check valve that prevents backflow of fluid or air into the syringe through the pipetting needles. A distribution manifold is connected to the selector valve and receives the fluid passing through the selector valve. The manifold has a plurality of distribution channels coupled to the syringes, to direct the fluid into the syringes. Each distribution channel has a manifold valve therein that prevents backflow of fluid into the manifold from the syringes.Type: ApplicationFiled: January 16, 2002Publication date: May 23, 2002Inventors: Romaine Maiefski, Don Wendell
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Patent number: 6355164Abstract: A fraction collection assembly having a frame and a dispensing head movably connected to the frame for movement about three axes. The dispensing head has a dispensing tube that receives and dispenses the sample portion. The dispensing head is movable between a dispensing position, a rinse position, and a pickup position. A receiving container with a receiving well is positioned to receive the sample portion of the selected sample dispensed from the dispensing tube when the dispensing head is in the dispensing position. The receiving well has a 1-to-1 corresponding position to the well from which the sample is originally taken from the supplying container. The rinse station is connected to the frame and positioned to removably receive the dispensing tube when the dispensing head is in the rinse position.Type: GrantFiled: May 11, 2000Date of Patent: March 12, 2002Assignee: Ontogen CorporationInventors: Don Wendell, Romaine Maiefski, Jonathan D. Krakover
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Patent number: 6309541Abstract: A multiple channel high throughput purification system for purifying a plurality of samples, preferably four or more samples from a chemical library. The high throughput purification uses chromatography, and more preferably, super critical fluid chromatography. Four parallel channels are provided in this system and coupled to a common analyzer and computer. The four channels direct the selected sample flow through a separator, such as an SFC column, a detector, such as a UV detector, to detect peaks within the sample flow, and a micro sample valve that splits a sampling of the flow to an analyzer, such as a mass spectrometer. The system also utilizes unique back pressure regulator assemblies and pressure relief assemblies to maintain a selected pressure within the purification channel. While the sample flow continues, the mass spectrometer simultaneously analyzes the sampling to determine if a target compound is within the sample portion.Type: GrantFiled: October 29, 1999Date of Patent: October 30, 2001Assignee: Ontogen CorporationInventors: Romaine Maiefski, Don Wendell, William C. Ripka, Jonathan D. Krakover
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Publication number: 20010013494Abstract: A multiple channel high throughput purification system for purifying a plurality of samples, preferably four or more samples from a chemical library. The high throughput purification uses chromatography, and more preferably, super critical fluid chromatography. Four parallel channels are provided in this system and coupled to a common analyzer and computer. The four channels direct the selected sample flow through a separator, such as an SFC column, a detector, such as a UV detector, to detect peaks within the sample flow, and a micro sample valve that splits a sampling of the flow to an analyzer, such as a mass spectrometer. The system also utilizes unique back pressure regulator assemblies and pressure relief assemblies to maintain a selected pressure within the purification channel. While the sample flow continues, the mass spectrometer simultaneously analyzes the sampling to determine if a target compound is within the sample portion.Type: ApplicationFiled: April 2, 2001Publication date: August 16, 2001Inventors: Romaine Maiefski, Don Wendell, William C. Ripka, Jonathan D. Krakover
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Patent number: 5976470Abstract: A wash station assembly and method for washing selected samples in a sample containing assembly. The wash station assembly includes a wash station having a frame and a fluid dispensing assembly connected to the frame. The fluid dispensing assembly has a selector valve that is connectable to a plurality of fluid lines and is adjustable to allow only one of the fluids to pass through the selector valve at a time. An array of syringes is coupled to the selector valve and positioned to receive the fluid passing through the selector valve. Each syringe includes a check valve that prevents backflow of fluid or air into the syringe through the pipetting needles. A distribution manifold is connected to the selector valve and receives the fluid passing through the selector valve. The manifold has a plurality of distribution channels coupled to the syringes, to direct the fluid into the syringes. Each distribution channel has a manifold valve therein that prevents backflow of fluid into the manifold from the syringes.Type: GrantFiled: May 29, 1998Date of Patent: November 2, 1999Assignee: Ontogen CorporationInventors: Romaine Maiefski, Don Wendell