Patents by Inventor Don Wesley Arnold
Don Wesley Arnold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230381781Abstract: Methods, devices, and systems for performing isoelectric focusing reactions are described. The systems or devices disclosed herein may comprise fixtures that have a membrane. In some instances, the disclosed devices may be designed to perform isoelectric focusing or other separation reactions followed by further characterization of the separated analytes using mass spectrometry. Two or more isoelectric focusing reactions may be performed in parallel. The disclosed methods, devices, and systems provide for fast, accurate separation and characterization of protein analyte mixtures or other biological molecules by isoelectric point.Type: ApplicationFiled: May 16, 2023Publication date: November 30, 2023Inventors: Luc BOUSSE, Don Wesley ARNOLD, Wesley CHANG, Erik GENTALEN, Eric GWERDER, Scott MACK
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Publication number: 20220088605Abstract: Methods, devices, and systems for performing isoelectric focusing reactions are described. The systems or devices disclosed herein may comprise fixtures that have a membrane. In some instances, the disclosed devices may be designed to perform isoelectric focusing or other separation reactions followed by further characterization of the separated analytes using mass spectrometry. The disclosed methods, devices, and systems provide for fast, accurate separation and characterization of protein analyte mixtures or other biological molecules by isoelectric point.Type: ApplicationFiled: December 7, 2021Publication date: March 24, 2022Inventors: Eric GWERDER, Scott MACK, Erik GENTALEN, Luc BOUSSE, Don Wesley Arnold
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Patent number: 11224875Abstract: Methods, devices, and systems for performing isoelectric focusing reactions are described. The systems or devices disclosed herein may comprise fixtures that have a membrane. In some instances, the disclosed devices may be designed to perform isoelectric focusing or other separation reactions followed by further characterization of the separated analytes using mass spectrometry. The disclosed methods, devices, and systems provide for fast, accurate separation and characterization of protein analyte mixtures or other biological molecules by isoelectric point.Type: GrantFiled: December 16, 2020Date of Patent: January 18, 2022Assignee: INTABIO, LLCInventors: Eric Gwerder, Scott Mack, Erik Gentalen, Luc Bousse, Don Wesley Arnold
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Publication number: 20210101152Abstract: Methods, devices, and systems for performing isoelectric focusing reactions are described. The systems or devices disclosed herein may comprise fixtures that have a membrane. In some instances, the disclosed devices may be designed to perform isoelectric focusing or other separation reactions followed by further characterization of the separated analytes using mass spectrometry. The disclosed methods, devices, and systems provide for fast, accurate separation and characterization of protein analyte mixtures or other biological molecules by isoelectric point.Type: ApplicationFiled: December 16, 2020Publication date: April 8, 2021Inventors: Eric GWERDER, Scott MACK, Erik GENTALEN, Luc BOUSSE, Don Wesley Arnold
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Patent number: 8795493Abstract: A flow controller which uses a combination of hydrostatic pressure and electroosmotic flow to control the flow of a fluid. A driving fluid (1204) whose flow rate is dependent on both hydrostatic pressures and electroosmotic flow can be used (a) directly as a working fluid in an operable device, for example a chromatograph, or (b) to displace a working fluid (1203) from a storage container (625) into an operable device (1301), or both (a) and (b). The driving fluid (1204) can be composed of one or more fluids. Part or all the driving fluid (1204) is passed through an electroosmotic device (100) so as to increase or decrease the flow rate induced by hydrostatic pressure.Type: GrantFiled: September 25, 2009Date of Patent: August 5, 2014Assignee: DH Technologies Development Pte. Ltd.Inventors: David W. Neyer, Phillip H. Paul, Don Wesley Arnold, Christopher G. Bailey
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Patent number: 7695603Abstract: Electroosmotic flow controllers and methods of fluid flow control are described. The invention uses an electroosmotically generated flow component in conjunction with a pressure driven flow component to modulate fluid flow. The devices and methods of the invention may include salt bridges for making electrical connection between a power supply and a channel filled with a porous dielectric material and a fluid. Embodiments including flow controllers and flow splitters are described as is their use in a variety of fluid handling applications.Type: GrantFiled: August 8, 2005Date of Patent: April 13, 2010Assignee: Eksigent Technologies, LLCInventors: Phillip H. Paul, Don Wesley Arnold, Christopher G. Bailey
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Publication number: 20100012497Abstract: A flow controller which uses a combination of hydrostatic pressure and electroosmotic flow to control the flow of a fluid. A driving fluid (1204) whose flow rate is dependent on both hydrostatic pressures and electroosmotic flow can be used (a) directly as a working fluid in an operable device, for example a chromatograph, or (b) to displace a working fluid (1203) from a storage container (625) into an operable device (1301), or both (a) and (b). The driving fluid (1204) can be composed of one or more fluids. Part or all the driving fluid (1204) is passed through an electroosmotic device (100) so as to increase or decrease the flow rate induced by hydrostatic pressure.Type: ApplicationFiled: September 25, 2009Publication date: January 21, 2010Inventors: David W. Neyer, Phillip H. Paul, Don Wesley Arnold, Christopher G. Bailey
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Patent number: 7597790Abstract: A flow controller which uses a combination of hydrostatic pressure and electroosmotic flow to control the flow of a fluid. A driving fluid (1204) whose flow rate is dependent on both hydrostatic pressures and electroosmotic flow can be used (a) directly as a working fluid in an operable device, for example a chromatograph, or (b) to displace a working fluid (1203) from a storage container (625) into an operable device (1301), or both (a) and (b). The driving fluid (1204) can be composed of one or more fluids. Part or all the driving fluid (1204) is passed through an electroosmotic device (100) so as to increase or decrease the flow rate induced by hydrostatic pressure.Type: GrantFiled: June 13, 2002Date of Patent: October 6, 2009Assignee: Eksigent Technologies, LLCInventors: David W. Neyer, Phillip H. Paul, Don Wesley Arnold, Christopher G. Bailey
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Publication number: 20040163957Abstract: A flow controller which uses a combination of hydrostatic pressure and electroosmotic flow to control the flow of a fluid. A driving fluid (1204) whose flow rate is dependent on both hydrostatic pressures and electroosmotic flow can be used (a) directly as a working fluid in an operable device, for example a chromatograph, or (b) to displace a working fluid (1203) from a storage container (625) into an operable device (1301), or both (a) and (b). The driving fluid (1204) can be composed of one or more fluids. Part or all the driving fluid (1204) is passed through an electroosmotic device (100) so as to increase or decrease the flow rate induced by hydrostatic pressure.Type: ApplicationFiled: December 10, 2003Publication date: August 26, 2004Inventors: David W. Neyer, Phillip H. Paul, Don Wesley Arnold, Christopher G. Bailey
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Publication number: 20020189947Abstract: Electroosmotic flow controllers and methods of fluid flow control are described. The invention uses an electroosmotically generated flow component in conjunction with a pressure driven flow component to modulate fluid flow. The devices and methods of the invention may include salt bridges for making electrical connection between a power supply and a channel filled with a porous dielectric material and a fluid. Embodiments including flow controllers and flow splitters are described as is their use in a variety of fluid handling applications.Type: ApplicationFiled: August 29, 2001Publication date: December 19, 2002Applicant: Eksigent Technologies LLPInventors: Phillip H. Paul, Don Wesley Arnold, Christopher G. Bailey