Patents by Inventor Don Wiley

Don Wiley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7262270
    Abstract: The present invention provides a fusion protein construct (gp41HA) consisting of the ectodomain of the HIV-1IIIB envelope glycoprotein gp41 fused to a fragment of the influenza virus HA2 hemagglutinin protein. Immunization in-vivo via an intraperitoneal prime followed by intranasal or intragastric boosts with gp41HA induces high concentrations of serum IgG antibodies and fecal IgA antibodies that reacted with gp41 in HIV-1IIIB viral lysate and are cross-reactive with gp41 in HIV-1MN lysate. Followup analyses by indirect immunofluorescence showed that both serum IgG and fecal IgA recognized human peripheral blood mononuclear cells infected with either syncytium-inducing (SI) or non-syncytium-inducing (NSI) North American HIV-1 field isolates, but not uninfected cells.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: August 28, 2007
    Assignee: Children's Medical Center Corporation
    Inventors: Winfried Weissenhorn, David Prashker, legal representative, Nicholas Mantis, Marian R. Neutra, Pamela Kozlowski, Don Wiley, deceased
  • Patent number: 7013599
    Abstract: A method of treating a distressed tree includes the steps of: creating a mixture comprising a fertilizer and a growth hormone and applying the mixture to a root area of the distressed tree.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: March 21, 2006
    Inventors: Don Wiley Smith, Peter Martin
  • Publication number: 20040194372
    Abstract: A method of treating a distressed tree includes the steps of: creating a mixture comprising a fertilizer and a growth hormone and applying the mixture to a root area of the distressed tree.
    Type: Application
    Filed: March 24, 2004
    Publication date: October 7, 2004
    Inventors: Don Wiley Smith, Peter Martin
  • Publication number: 20040096458
    Abstract: The present invention provides a fusion protein construct (gp41HA) consisting of the ectodomain of the HIV-1IIIB envelope glycoprotein gp41 fused to a fragment of the influenza virus HA2 hemagglutinin protein. Immunization in-vivo via an intraperitoneal prime followed by intranasal or intragastric boosts with gp41HA induces high concentrations of serum IgG antibodies and fecal IgA antibodies that reacted with gp41 in HIV-1IIIB viral lysate and are cross-reactive with gp41 in HIV-1MN lysate. Follow up analyses by indirect immunofluorescence showed that both serum IgG and fecal IgA recognized human peripheral blood mononuclear cells infected with either syncytium-inducing (SI) or non-syncytium-inducing (NSI) North American HIV-1 field isolates, but not uninfected cells.
    Type: Application
    Filed: September 5, 2003
    Publication date: May 20, 2004
    Inventors: Winfried Weissenhorn, Don Wiley, Nicholas Mantis, Marian R. Neutra, Pamela Kozlowski
  • Patent number: 4353544
    Abstract: A seat equipped frame, vertically slidably supported on an upright pole having handle bars at its upper end, is provided with pedals and a crank angularly rotating a reel about a horizontal axis for winding an elongated flexible member thereon, secured at one end to an intermediate portion of the pole, for lifting the frame and an occupant in response to angular rotation of the reel in one direction. Downward movement of the frame, from its lifted position, is retarded by air trapped below a piston, moved upwardly with the frame, in a tube to form a brake.
    Type: Grant
    Filed: November 13, 1980
    Date of Patent: October 12, 1982
    Inventor: W. Don Wiley
  • Patent number: D260038
    Type: Grant
    Filed: June 15, 1979
    Date of Patent: July 28, 1981
    Inventor: W. Don Wiley