Abstract: The present disclosure relates to a communication systems for electronic ophthalmic devices. In certain embodiments, the ophthalmic device may comprise a light-emitting device. The ophthalmic device may comprise a light detection device. The light detection device may be used to receive light signals. The light-emitting device may be used to transmit light signals.

Abstract: A structure for damping at a fluid manifold assembly for an engine is generally provided. The fluid manifold assembly includes a first walled conduit defining a first fluid passage therewithin. A flow of fluid defining a first frequency is permitted through the first fluid passage. A second walled conduit includes a pair of first portions each coupled to the first walled conduit. A second portion is coupled to the pair of first portions. A second fluid passage is defined through the first portion and the second portion in fluid communication with the first fluid passage. The flow of fluid is permitted through the second fluid passage at a second frequency approximately 180 degrees out of phase from the first frequency.

Abstract: A powered ophthalmic lens having an electronic system is described herein configured to communicate with an external device using an ultrasound module for creating a sound pressure wave(s) to be transmitted through a medium, e.g. air, to an external device. The ophthalmic lens includes at least one ultrasound module having at least one transducer such as a pair of transmit and receive transducers, a transceiver transducer or a plurality of transducers. The ultrasound module includes additional components for the creation and reception of the sound pressure wave(s). In an alternative embodiment, there is one ultrasound module with a multiplexer connected to a plurality of transducers. In at least one embodiment, the sound pressure wave(s) encodes a message from the external device to the contact lens. In at least one alternative embodiment, the sound pressure wave(s) encodes a message from the contact lens to the external device.

Abstract: Disclosed herein are combination therapies for the treatment of heart failure using a cardiac myosin activator, such as omecamtiv mecarbil, and a sinus node If current inhibitor, such as ivabradine. Also disclosed herein are compositions comprising a cardiac myosin activator and a sinus node If current inhibitor.

Abstract: Disclosed are methods for building a sequence activity model with reference to structural data, which model can be used to guide directed evolution of proteins having beneficial properties. Some embodiments use genetic algorithms and structural data to filter out uninformative data. Some embodiments use a support vector machine to train the sequence activity model. The filtering and training methods can generate a sequence activity model having higher predictive power than conventional modeling methods. Systems and computer program products implementing the methods are also provided.

Abstract: The present disclosure is directed to a sealing system for a turbine engine including an engine component, the engine component defining an oblique sealing surface defining an annular shape. The oblique sealing surface defines an oblique angle with a centerline of the engine component. The sealing system includes a seal housing and a seal ring. The seal housing is annular and includes a groove that is defined by a first sidewall, a second sidewall, and an end wall connecting the first sidewall and the second sidewall. The seal ring is positioned at least partially within the groove in the seal housing. The seal ring defines a seal contact surface for forming a seal with the oblique sealing surface of the engine component.

Abstract: A sleeve feeding device includes a core extending along a feed axis and having a hollow interior. One or more slots are in the outer surface of the core extending in first and second directions. A sleeve pusher assembly is located within the hollow interior and has retractable fingers that protrude from the slots in the core, allowing the sleeve pusher assembly to engage a sleeve on the outer surface of the core and feed it along the feed axis in the first direction. When withdrawn in the second direction, the fingers of the sleeve pusher assembly retract within the slots upon encountering the next sleeve. Once clear, the fingers again protrude and the next sleeve is fed along the outer surface of the core.

Abstract: A powered ophthalmic lens having an electronic system is described herein configured to communicate with an external device using an ultrasound module for creating a sound pressure wave(s) to be transmitted through a medium, e.g. air, to an external device. The ophthalmic lens includes at least one ultrasound module having at least one transducer such as a pair of transmit and receive transducers, a transceiver transducer or a plurality of transducers. The ultrasound module includes additional components for the creation and reception of the sound pressure wave(s). In an alternative embodiment, there is one ultrasound module with a multiplexer connected to a plurality of transducers. In at least one embodiment, the sound pressure wave(s) encodes a message from the external device to the contact lens. In at least one alternative embodiment, the sound pressure wave(s) encodes a message from the contact lens to the external device.

Abstract: A pair of ophthalmic lens having an electronic system is described herein for communicating between them using ultrasound transducers for creating a sound pressure wave(s) to be scattered by the nose of the wearer of the ophthalmic lenses. The ophthalmic lenses include at least one ultrasound module having at least one transducer such as a pair of transmit and receive transducers, a transceiver transducer or a plurality of transducers. The ultrasound module includes additional components for the creation and reception of the sound pressure wave(s). In at least one embodiment, the sound pressure wave(s) encodes a message between the contact lenses. In at least one embodiment, the ophthalmic lenses include contact lenses or intraocular lenses.

Abstract: A conveyor system comprises a track extending along a conveying path, and one or more carriages having a mounting section slidably engaging the track, with a vacuum connection being formed in the mounting section. A driving mechanism moves the carriages along the conveying path. A plurality of vacuum valves connected to the track along the conveying path, and a vacuum source is connected to the plurality of vacuum valves to supply vacuum thereto. The conveyor system is configured to selectively supply vacuum to the vacuum connection of the least one carriage via the plurality of vacuum valves based on a proximity of the at least one carriage thereto.

Abstract: A contact lens having an electronic system is described herein to provide lens accommodation using a distance measurement determined from an ultrasound time of flight signal. In at least one embodiment, the contact lens includes an ultrasound module, a system controller, a timing circuit, and an actuator. In at least one embodiment, the ultrasound module includes at least one transducer configured to emit a sound pressure wave outwardly and receive a reflected sound pressure wave from an object. A timer may track an elapsed time between generation and detection of the sound pressure wave by the at least one transducer to determine the distance to the object. In at least one embodiment, lens accommodation is further achieved using a communication link between a pair of contact lenses to determine a convergence angle based on independent distance measurements generated by each contact lens.

Abstract: A trigger bar for a semi-automatic firearm. The trigger bar includes a longitudinal body with a rearward lateral arm. The arm includes surfaces for engaging the sear and the drop safety lifter of the firearm. The surfaces are configured to reduce trigger pre-travel distances by reducing a trigger travel distance prior to drop safety lifter engagement, sear engagement, and striker release. An over-travel stop reduces a trigger over-travel distance.

Abstract: The problems of efficiency and safety when exercising is solved in at least one aspect while maintaining low-complexity and portability by use of the presented translating exercise lifting bar. Further provided here is an exercise lifting bar having hand grips with integral loading surfaces, the loading surfaces having plates applied. Also provided is an exercise lifting bar with a spring to and resist the translation, a translation limiter to limit the motion between the members, and an attachment feature configured to connect a cable.

Abstract: Methods and computer software for options trading, and more specifically, for analyzing a potential options trade instantaneously are described.

Abstract: A sealing bar assembly for a packaging machine includes a mounting frame, first and second sealing bar carriages carried by the mounting frame, at least one of the first and second sealing bars being movable with respect to the mounting frame, first and second sealing bars mounted, respectively, to the first and second sealing bar carriages and movable therewith, the first and second bars including, respectively, first and second opposed sealing surfaces, at least a first electromagnet assembly arranged adjacent to the first sealing bar, and a controller configured to selectively energize the first electromagnet assembly to move the first and second opposed sealing surfaces into and out of engagement across a web of packaging material passing therebetween.

Abstract: Provided is an exercise lifting bar having at least two hand grips, an integral loading surface for holding optional plate weights coupled to each hand grip, the paired or coupled grips and loading surfaces thereby defining a member; the members further being substantially cylindrical, collinear, and operable to translate relative to one another. Also included is a translation limiter to limit the motion between the members. Methods of assembly of the exercise lifting bar are also provided.

Abstract: A gas turbine engine comprises a fan, a compressor, a turbine having first stage blades and second stage blades, the first stage blades rotates in a first direction and the second stage blades rotates in a second direction opposite the first direction. The first stage blades are directly adjacent to one another, a drive in operable input connection with the fan and in operable output connection with the first stage blades and the second stage blades, the first stage blades and the second stage blades driving the fan through the drive.

Abstract: A trigger bar for a semi-automatic firearm. The trigger bar includes a longitudinal body with a rearward lateral arm. The arm includes surfaces for engaging the sear and the drop safety lifter of the firearm. The surfaces are configured to reduce trigger pre-travel distances by reducing a trigger travel distance prior to drop safety lifter engagement, sear engagement, and striker release. An over-travel stop reduces a trigger over-travel distance.