Abstract: The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of renal and cardiovascular disorders and of ischemia reperfusion injuries.

Abstract: Embodiments of the present invention provide an integrated circuit (IC) in which power to input output (IO) drivers may be distributed within unused areas over macro processing circuits. This IC includes a long distance power and ground distribution network, an input output (IO) power and ground distribution network, a number of macro processing circuits, and IO circuits. The long distance power and ground distribution network electrically couples to the IO power and ground distribution network. Both the power and ground distribution networks may be located within the upper level conductive layers. IO power and ground distribution network locally supplies power and ground to IO circuits. Macro processing circuits may be located beneath the power distribution network as some macro processing circuits do not require access to upper level conductive layers. By placing these macro processing circuits beneath these power distribution networks, die size may be reduced.

Abstract: Embodiments of the present invention provide an integrated circuit (IC) in which power to input output (IO) drivers may be distributed within unused areas over macro processing circuits. This IC includes a long distance power and ground distribution network, an input output (IO) power and ground distribution network, a number of macro processing circuits, and IO circuits. The long distance power and ground distribution network electrically couples to the IO power and ground distribution network. Both the power and ground distribution networks may be located within the upper level conductive layers. IO power and ground distribution network locally supplies power and ground to IO circuits. Macro processing circuits may be located beneath the power distribution network as some macro processing circuits do not require access to upper level conductive layers. By placing these macro processing circuits beneath these power distribution networks, die size may be reduced.