Patents by Inventor Donald Bellgrau
Donald Bellgrau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8221763Abstract: Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by administration of a yeast vehicle and an antigen that is not complexed to the yeast vehicle is disclosed.Type: GrantFiled: August 12, 2009Date of Patent: July 17, 2012Assignees: GlobeImmune, Inc., The Regents of the University of Colorado, a body corporateInventors: Richard C. Duke, Donald Bellgrau, Alex Franzusoff, Cara C. Wilson
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Patent number: 8153136Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: GrantFiled: December 15, 2008Date of Patent: April 10, 2012Assignees: GlobeImmune, Inc., The Regents of the University of ColoradoInventors: Alex Franzusoff, Donald Bellgrau
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Patent number: 8067559Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: GrantFiled: December 15, 2008Date of Patent: November 29, 2011Assignee: GlobeImmune, Inc.Inventors: Alex Franzusoff, Donald Bellgrau
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Publication number: 20110150909Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: ApplicationFiled: December 21, 2009Publication date: June 23, 2011Inventors: Alex Franzusoff, Donald Bellgrau
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Publication number: 20100215678Abstract: Disclosed are newly discovered Ras mutations and combinations of mutations, proteins and peptides and fusion proteins containing these mutations, nucleic acid molecules encoding such proteins, peptides, and fusion proteins, and a variety of tools and diagnostic, therapeutic, and screening methods associated with the use of such mutations.Type: ApplicationFiled: May 6, 2010Publication date: August 26, 2010Applicant: GLOBEIMMUNE, INC.Inventors: Zhimin Guo, Yingnian Lu, Donald Bellgrau, Alex Franzusoff
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Patent number: 7745128Abstract: Disclosed are newly discovered Ras mutations and combinations of mutations, proteins and peptides and fusion proteins containing these mutations, nucleic acid molecules encoding such proteins, peptides, and fusion proteins, and a variety of tools and diagnostic, therapeutic, and screening methods associated with the use of such mutations.Type: GrantFiled: March 9, 2007Date of Patent: June 29, 2010Assignee: GlobeImmune, Inc.Inventors: Zhimin Guo, Yingnian Lu, Donald Bellgrau, Alex Franzusoff
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Publication number: 20090304741Abstract: Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by administration of a yeast vehicle and an antigen that is not complexed to the yeast vehicle is disclosed.Type: ApplicationFiled: August 12, 2009Publication date: December 10, 2009Applicants: GLOBELMMUNE, INC., THE REGENTS OF THE UNIVERSITY OF COLORADOInventors: RICHARD C. DUKE, DONALD BELLGRAU, ALEX FRANZUSOFF, CARA C. WILSON
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Patent number: 7595060Abstract: Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by administration of a yeast vehicle and an antigen that is not complexed to the yeast vehicle is disclosed.Type: GrantFiled: June 1, 2006Date of Patent: September 29, 2009Assignees: GlobeImmune, Inc., The Regents of the University of ColoradoInventors: Richard C. Duke, Donald Bellgrau, Alex Franzusoff, Cara C. Wilson
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Patent number: 7563447Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: GrantFiled: June 25, 2007Date of Patent: July 21, 2009Assignee: GlobeImmune, Inc.Inventors: Alex Franzusoff, Donald Bellgrau
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Publication number: 20090142366Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: ApplicationFiled: December 15, 2008Publication date: June 4, 2009Applicants: GlobeImmune, Inc., The Regents of the University of ColoradoInventors: Alex Franzusoff, Donald Bellgrau
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Publication number: 20090142367Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: ApplicationFiled: December 15, 2008Publication date: June 4, 2009Applicants: GlobeImmune, Inc., The Regents of the University of ColoradoInventors: Alex Franzusoff, Donald Bellgrau
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Publication number: 20090098154Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: ApplicationFiled: December 15, 2008Publication date: April 16, 2009Applicant: Globelmmune, Inc.Inventors: Alex Franzusoff, Donald Bellgrau
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Patent number: 7465454Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: GrantFiled: December 16, 2003Date of Patent: December 16, 2008Assignee: GlobeImmune, Inc.Inventors: Alex Franzusoff, Donald Bellgrau
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Publication number: 20080069833Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: ApplicationFiled: June 25, 2007Publication date: March 20, 2008Applicant: GLOBEIMMUNE, INC.Inventors: Alex Franzusoff, Donald Bellgrau
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Publication number: 20070224208Abstract: Disclosed are newly discovered Ras mutations and combinations of mutations, proteins and peptides and fusion proteins containing these mutations, nucleic acid molecules encoding such proteins, peptides, and fusion proteins, and a variety of tools and diagnostic, therapeutic, and screening methods associated with the use of such mutations.Type: ApplicationFiled: March 9, 2007Publication date: September 27, 2007Applicant: GLOBEIMMUNE, INC.Inventors: Zhimin Guo, Yingnian Lu, Donald Bellgrau, Alex Franzusoff
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Publication number: 20070166323Abstract: Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by administration of a yeast vehicle and an antigen that is not complexed to the yeast vehicle is disclosed.Type: ApplicationFiled: June 1, 2006Publication date: July 19, 2007Applicants: Regents of the University of Colorado, GlobeImmune, Inc.Inventors: Richard Duke, Donald Bellgrau, Alex Franzusoff, Cara Wilson
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Patent number: 7083787Abstract: Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by administration of a yeast vehicle and an antigen that is not complexed to the yeast vehicle is disclosed.Type: GrantFiled: November 15, 2001Date of Patent: August 1, 2006Assignees: GlobeImmune, Inc., The Regents of the University of ColoradoInventors: Richard C. Duke, Donald Bellgrau, Alex Franzusoff, Cara C. Wilson
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Publication number: 20060104986Abstract: Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by administration of a yeast vehicle and an antigen that is not complexed to the yeast vehicle is disclosed.Type: ApplicationFiled: November 15, 2001Publication date: May 18, 2006Inventors: Richard Duke, Donald Bellgrau, Alex Franzusoff, Cara Wilson
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Publication number: 20040224389Abstract: This invention discloses a novel method for propagation of viral vectors encoding proteins that induce apoptosis. The invention also discloses viral vectors produced by such methods and cells transfected with such vectors. Also disclosed are methods for suppressing T-lymphocyte-mediated graft rejection, for suppressing T-lymphocyte-mediated disease and for inducing apoptosis in cancer cells.Type: ApplicationFiled: April 14, 2004Publication date: November 11, 2004Applicant: The Regents of the University of ColoradoInventors: Donald Bellgrau, Richard C. Duke, Jerome B. Schaack
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Publication number: 20040156858Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.Type: ApplicationFiled: December 16, 2003Publication date: August 12, 2004Inventors: Alex Franzusoff, Donald Bellgrau