Abstract: A blood sampling device includes an expansible, flexible container which, when unfilled, lies flat with its opposed sides together. The container is connected to a support having a passage for connecting the container with a needle cannula. A manually operable valve is disposed between the passage and the container. A gas vent communicates with the passage and has a hydrophobic filter for allowing air in the needle and passage to escape without entering the collection chamber of the container. The container has an isolation chamber at the proximal end for isolating air or air bubbles that might enter the collection chamber as a result of error in sampling technique. By hand manipulation of the container, such air bubbles can be moved from the collection chamber into the isolation chamber to isolate the air bubbles and prevent further absorption of oxygen from such air bubbles into the blood sample in the collection chamber.

Abstract: A blood collection needle and tube holder having a barrel open at one end for receiving a blood collection tube and having an end wall at the opposite end carrying an axially extending double-ended needle cannula. The barrel has longitudinally extending, resilient, interior walls inclined from the open end inwardly toward the longitudinal axis of the barrel whereby tubes of different sizes can be selectively inserted in the holder and guided by the inclined resilient walls. A size range pre-adjustment can be provided to change the angle between the longitudinal axes of the guide arms and the longitudinal axis of the barrel.