Abstract: Binding members for alpha chain of receptor for granulocyte macrophage colony stimulating factor (GM-CSFR?), especially antibody molecules. Use of the binding members in treating inflammatory and autoimmune diseases, e.g. rheumatoid arthritis, asthma, allergic response, multiple sclerosis, myeloid leukaemia and atherosclerosis.

Abstract: Disclosed is a flexible barrier glove manufactured by coating a glove liner with a mixture that includes polyurethane resin and an antibacterial agent.

Abstract: The present invention provides methods for preparing and administering a tumor vaccine. The processes include resecting tumors and isolating tumor cells, followed by treatment with ultraviolet radiation to activate the tumor cells. Cells can then be mixed with an unmethylated single stranded oligodeoxynucleotide chain adjuvant to formulate a vaccine and then administered to a subject. The vaccines can be autologous, allogeneic or hybrids thereof to the subject.

Abstract: This invention discloses how Virtual Database Technology can be used to make disparate data appear to be (or act as) the sort of uniform data one expects to find within a single relational database. In particular, we show how to process queries similar to those one might use in a database, even though the underlying data may be missing some of the capabilities that are required by normal databases. Whereas traditional databases require that all the tuples in a table be stored, our approach allows queries over tables where the tuples are generated as required from the data sources, and may not be stored anywhere. We show how such facilities can be used as a new foundation for Internet search.

Abstract: An apparatus and methods for treating lesions on skin are presented. The apparatus collects information about a lesion and can automatically determine a course of treatment for the lesion. The device can include a controller that positions the nozzle proximate to a surface region of the lesion and automatically dispenses a pulse of the cryogenic fluid from the nozzle. The controller then positions the nozzle proximate to another surface region of the lesion and automatically dispenses a pulse of the cryogenic fluid from the nozzle.

Abstract: The invention is a device that generates a cool fluid stream that has properties adequate to remove superficial layers of tissue. The stream is generated to render the target tissue much more brittle in its mechanical behavior than it would otherwise be; principally by temperature and pressure rise and decay rates. The primary intended use is for dermatologic skin resurfacing, though it may be used to remove superficial layers of tissue anywhere in the body.

Abstract: An apparatus and methods for treating lesions on skin are presented. The apparatus collects information about a lesion and can automatically determine a course of treatment for the lesion. The device can include a controller that positions the nozzle proximate to a surface region of the lesion and automatically dispenses a pulse of the cryogenic fluid from the nozzle. The controller then positions the nozzle proximate to another surface region of the lesion and automatically dispenses a pulse of the cryogenic fluid from the nozzle.

Abstract: An apparatus and methods for treating lesions on skin are presented. The apparatus collects information about a lesion and can automatically determine a course of treatment for the lesion. The device can include a controller that positions the nozzle proximate to a surface region of the lesion and automatically dispenses a pulse of the cryogenic fluid from the nozzle. The controller then positions the nozzle proximate to another surface region of the lesion and automatically dispenses a pulse of the cryogenic fluid from the nozzle.

Abstract: The present invention is a system for the non-contact stimulation of excitable tissue. A primary purpose is reducing the perception of pain in those people who suffer from persistent pain. Apparatus is described for adjusting the position of the stimulation region.

Abstract: A data processing system adapted to display a three dimensional representation of an individual patient's body, key functions, and current conditions, and to advise of options for improving wellness is disclosed. The system can be used, for example, to display a three dimensional image of a patient's body in a first state, to receive age and disease assumptions, and to display a three dimensional image corresponding to the received age and disease assumptions, thereby simulating the impact of lifestyle choices by representing the patient's body as it would appear at various ages having various diseases.

Abstract: An improved solution for use in the removal of cataractous lenses via liquefracture is described. The liquefracture solution contains a viscosity-enhancing agent to increase the residence time of the solution in the heating chamber of the liquefracture handpiece, thereby increasing the expulsion force of the solution from the handpiece (i.e., “pulse force”). An agent that releases gas when the liquefracture solution is heated in the handpiece may also be included in the solution, thereby also enhancing the pulse force of the solution upon expulsion from the handpiece. The solution preferably also contains a partially water-soluble agent that forms a temporarily insoluble precipitate when heated in a liquefracture handpiece. The precipitate acts as an abrasive agent when expelled with the liquefracture solution from the handpiece, thereby facilitating the cutting and disintegration of the cataractous lens material.

Abstract: A blood vessel occlusion system and method includes a handheld probe including a power source, the probe being adapted to transmit energy from the power source through a body surface and into a target blood vessel, for example a varicose vein. Further included is a manual or automatic switch mechanism adapted to enable and disable the power source in response to a predetermined level of compression applied, by means of the probe against the target blood vessel.

Abstract: An automatic faucet system includes a sensor and a controller. The sensor includes an emitter constructed and arranged to emit light having a first polarization toward an object. The sensor further includes a detector configured to detect light reflected from the object having a second polarization that is different from the first polarization. The controller is operatively coupled to the detector. The controller is configured to supply water to a faucet, or other water supply, upon sensing by the detector the light having the second polarization. By sensing in such a manner, the level of false positive readings in the system is reduced. The detector is further configured to determine the location of the object so that the faucet is only activated when the object is in close proximity to the faucet.

Abstract: The invention computes approximate origins of data packets transmitted over the Internet. Law enforcement agencies and network operators can use it to assign responsibility for observed Internet activities. The invention uses a small number of cooperative locations (incoming links on routers or switches) to provide link identification data: whether a packet or did or did not traverse that location. The system uses these cooperative places to generate the link signature of a data packet—which places observed and did not observe the packet. Potential origin locations are divided into blocks that have the same link signatures to given destination locations. The blocks are used to generate reverse routing data, potential source addresses for different link signatures. Variations of the invention store relevant link identification and reverse routing data to find the origins of past packets or to compute the origins of packets from partial information about packets of interest.

Abstract: A blood vessel occlusion system and method includes a handheld probe including a power source, the probe being adapted to transmit energy from the power source through a body surface and into a target blood vessel, for example a varicose vein. Further included is a manual or automatic switch mechanism adapted to enable and disable the power source in response to a predetermined level of compression applied, by means of the probe against the target blood vessel. When the blood vessel is compressed sufficiently to collapse and substantially slow or substantially prevent a flow of blood therethrough, the power source is activated and the vessel is cauterized, leaving the blood vessel in a condition that is resistant to recanalization.

Abstract: A minimally-invasive surgery apparatus for causing the lumen of a vein to collapse to prevent blood flow through the vein, e.g., a varicose vein or a side branch of the saphenous vein, includes an electrode which is electrically connected to a power source, and the electrode is percutaneously advanced into the vein. Then, the power source is activated to energize the electrode and thus the blood vein until the blood vein sufficiently collapses to block the lumen of the vein. A feedback loop is also provided for sensing electrical impedance of the tissue within the vein being energized and for deenergizing the electrode when the impedance reaches a predetermined value.

Abstract: A minimally-invasive surgery apparatus for causing the lumen of a vein to collapse to prevent blood flow through the vein, e.g., a varicose vein or a side branch of the saphenous vein, includes an electrode which is electrically connected to a power source, and the electrode is percutaneously advanced into the vein. Then, the power source is activated to energize the electrode and thus the blood vein until the blood vein sufficiently collapses to block the lumen of the vein. A feedback loop is also provided for sensing electrical impedance of the tissue within the vein being energized and for deenergizing the electrode when the impedance reaches a predetermined value. The apparatus can also be used to block a fallopian tube.

Abstract: A shunt for relieving hydrocephalus has a closed distal end and an aperture formed in the distal end. A hollow hypotube has a distal end, and the hypotube holds an image fiber which protrudes beyond the distal end of the hypotube. The hypotube is positioned in the shunt with the distal end of the hypotube abutting the distal end of the shunt and the image fiber protruding through the aperture. The hypotube with shunt can then be advanced into the brain of a patient, while the surgeon views the path of advancement on a nearby video monitor which is connected to the image fiber. In an alternate embodiment, the distal end of the image fiber is flush with the distal end of the hypotube. The shunt has a slit formed in its distal end, and the hypotube with image fiber can be selectively advanced through the slit to view the area of the brain beyond the catheter.

Abstract: A shunt for relieving hydrocephalus has a closed distal end and an aperture formed in the distal end. A hollow hypotube has a distal end, and the hypotube holds an image fiber which protrudes beyond the distal end of the hypotube. The hypotube is positioned in the shunt with the distal end of the hypotube abutting the distal end of the shunt and the image fiber protruding through the aperture. The hypotube with shunt can then be advanced into the brain of a patient, while the surgeon views the path of advancement on a nearby video monitor which is connected to the image fiber. In an alternate embodiment, the distal end of the image fiber is flush with the distal end of the hypotube. The shunt has a slit formed in its distal end, and the hypotube with image fiber can be selectively advanced through the slit to view the area of the brain beyond the catheter.

Abstract: A minimally-invasive surgery apparatus for causing the lumen of a vein to collapse to prevent blood flow through the vein, e.g., a varicose vein or a side branch of the saphenous vein, includes an electrode which is electrically connected to a power source, and the electrode is percutaneously advanced into the vein. Then, the power source is activated to energize the electrode and thus the blood vein until the blood vein sufficiently collapses to block the lumen of the vein. A feedback loop is also provided for sensing electrical impedance of the tissue within the vein being energized and for deenergizing the electrode when the impedance reaches a predetermined value.