Abstract: Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.

Abstract: Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.

Abstract: Devices and methods for reshaping a mitral valve annulus are provided. One device according to the invention is configured for deployment in the right atrium and is shaped to apply a force along the atrial septum. The device causes the atrial septum to deform and push the anterior leaflet of the mitral valve in a posterior direction for reducing mitral valve regurgitation. Another embodiment of a device is deployed in the left ventricular outflow tract at a location adjacent the aortic valve. The device may be expandable for urging the anterior leaflet toward the posterior leaflet. Another embodiment of the device includes a first anchor, a second anchor, and a bridge, with the bridge having sufficient length to reach from the coronary sinus to the right atrium and/or superior or inferior vena cava. In a further embodiment a device includes a middle anchor positioned on the bridge between the distal and proximal anchors.

Abstract: A threaded device such as a self-tapping screw or bolt, particularly for use in medical applications, provides a low-torque design that prevents a steady increase in the amount of torque necessary to drive the device into material as the device progresses. The design includes a thread that has a proximal section with a reduced diameter, thereby reducing the overall contact area between the thread and the material.

Abstract: A system and method for intracranial access is disclosed. In particular, a drill stop is shown providing a way to control the penetration of a drill bit as an access hole into the brain is being formed. Access to a desired location is achieved using a catheter guide device. Also disclosed is a mechanism by which multiple diagnostic and treatment devices can be placed at a desired location in brain tissue without the need for more than one access hole. A drainage catheter is disclosed with a mechanism to allow both drainage and to allow intracranial pressure measurement.

Abstract: A multiple lumen access device for use in providing a single entry port into the human body for selectively introducing medical implements therethrough and for providing simultaneous auxiliary access into the body. The multiple lumen access device includes a multi-lumen sheath which may have an outer tube and structure defining a device lumen located therein. The inner structure may be an inner wall or inner tube. The outer tube and inner structure are located so as to define at least one auxiliary lumen. Some embodiments include flexible inner walls which can be flexed between relaxed and expanded/contracted positions wherein the relative cross-sectional areas of the device lumen and auxiliary lumens are varied. The access device further includes a valve which provides sealing of the device lumen. The valve may be provided in a lumen junction housing or separate from the housing either permanently or removably connected with the device lumen.

Abstract: A catheter and a method for using the catheter for site specific delivery of agents to or collecting agents from biological spaces. The catheter includes an inner shaft longitudinally movable within and outer shaft, each shaft having at least one balloon and at least one lumen formed therein. The catheter prevents leaking through a membrane by sealing the tip passageway through the membrane with inflatable balloons on either side of the membrane. Further, the inflated balloons secure the position of the catheter relative to the biological membrane and biological space targeted for therapy or diagnosis.

Abstract: A system for delivering medicaments to tissue including a delivery member and an optical fiber formed together into a unitary structure. The optical fiber has an inlet attached to a laser energy source and an outlet for emitting laser energy. The delivery member has an inlet attached to a medicament source and an outlet for injecting medicament. A handpiece is adapted to receive the ablating and injecting device in a controlled and movable relationship and may include at least one tissue stabilizing member thereon. In use, the distal end of the handpiece is placed against tissue to be ablated. The optical fiber is advanced into the tissue while emitting laser energy thereby ablating the tissue and forming a channel therein. During retraction, medicament may be injected into the channel or into the tissue surrounding the channel.

Abstract: A catheter and a method for using the catheter for site specific delivery of agents to or collecting agents from biological spaces. The catheter includes an inner shaft longitudinally movable within and outer shaft, each shaft having at least one balloon and at least one lumen formed therein. The catheter prevents leaking through a membrane by sealing the tip passageway through the membrane with inflatable balloons on either side of the membrane. Further, the inflated balloons secure the position of the catheter relative to the biological membrane and biological space targeted for therapy or diagnosis.

Abstract: The present invention provides a device for efficiently coupling a pressure monitoring device to a pressure transducer. In addition, the present invention reduces or eliminates the likelihood air will be unintentionally injected into the pressure monitoring device while connecting the pressure monitoring device to a pressure transducer. In one embodiment, the present invention includes a pressure monitoring coupler comprising a sealing member and a device body. The sealing member comprises a sealing flange connected to an engagement member. The engagement member includes a first and second O-ring positioned thereon. The device body comprises a pressurizing lumen and an intersecting monitoring lumen in communication with a receiving aperture. During use, a pressure monitoring catheter is inserted into a patient's tissue. The pressure monitoring catheter and a transducer are connected to the device body of the present invention.

Abstract: A plurality of infusion pump modules are detachably connected to a portable central management unit. The modules can be programmed by the central management unit, and their operating information displayed by the central management unit, when they are connected to it; yet the modules, once programmed, can operate independently when detached from the central mangagement unit, and they can display limited operational information on their own.

Abstract: A linear peristaltic pump, and a disposable casette therefor, particularly suitable for the infusion of parenteral fluids. The pump includes a housing having a power-driven shaft and a series of small bearing assemblies having their inner members eccentrically mounted upon that shaft. A thin elastomeric membrane extends along the series of bearing assemblies for engagement with the outer members thereof along a first band or linear zone of contact lying in the same plane as the axis of the shaft. The disposable casette is removably supported by the housing and takes the form of a rigid, planar, perimetric frame having an opening across which is stretched a section of elastomeric tubing.