Patents by Inventor Donald E. Ganem

Donald E. Ganem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human herpesvirus type 8 isolated from human lymphoma cell line
    Patent number: 6149918
    Abstract: A human lymphoma cell line containing a human herpesvirus type 8 (HHV-8) capable of in vitro growth and which produces HHV-8 virus particles upon induction of lytic viral growth is provided. Virus produced by the cell line of the invention is useful for the production of antibodies to an HHV-8 virus particle, viral protein, or viral peptide. Methods of screening a biological sample for the presence of HHV-8 virus particles, viral protein, or viral peptide from a human suspected of being infected with HHV-8 are provided as are methods of screening a biological sample of the human for antibodies to HHV-8.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: November 21, 2000
    Assignee: The Regents of the University of California
    Inventors: Michael S. McGrath, Brian Herndier, Valerie L. Ng, Donald E. Ganem
  • Kaposi's Syndrome Herpesvirus protease and assembly protein compositions and methods
    Patent number: 6033894
    Abstract: Kaposi's Sarcoma Herpesvirus (KSHV) protease and assembly protein sequences are disclosed. Also disclosed are polynucleotides that encode the protease and assembly protein. The invention includes screening and detection methods, as well as KSHV protease inhibitory compositions.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: March 7, 2000
    Assignee: The Regents of the University of California
    Inventors: Charles S. Craik, Ay.cedilla.e Unal, Donald E. Ganem
  • Isolated human herpesvirus type 8 sequences and uses thereof
    Patent number: 5861240
    Abstract: Isolated human herpesvirus type 8 nucleic acid sequences expressed in latently infected human cells including primary Kaposi's sarcoma cells, primary pulmonary tumor cells, and a body cavity based lymphoma cell line are disclosed. Methods of detecting HHV-8 infection and methods of inhibiting expression of the nucleic acid sequences in vivo are also disclosed.
    Type: Grant
    Filed: February 28, 1996
    Date of Patent: January 19, 1999
    Assignee: The Regents of the University of California
    Inventors: Donald E. Ganem, Weidong Zhong