Patents by Inventor Donald E. Schmidt, Jr.

Donald E. Schmidt, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PURIFYING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES
    Publication number: 20110257364
    Abstract: Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
    Type: Application
    Filed: November 16, 2010
    Publication date: October 20, 2011
    Applicant: THERAVANCE, INC.
    Inventors: Donald E. SCHMIDT, JR., Jeanmarie Donovan Sganga
  • Process for purifying glycopeptide phosphonate derivatives
    Patent number: 7858583
    Abstract: Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
    Type: Grant
    Filed: November 17, 2008
    Date of Patent: December 28, 2010
    Assignee: Theravance, Inc.
    Inventors: Donald E. Schmidt, Jr., Jeanmarie Donovan Sganga
  • PROCESS FOR PURIFYING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES
    Publication number: 20090215673
    Abstract: Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
    Type: Application
    Filed: November 17, 2008
    Publication date: August 27, 2009
    Inventors: Donald E. Schmidt, JR., Jeanmarie Donovan Sganga
  • Process for purifying glycopeptide phosphonate derivatives
    Patent number: 7468420
    Abstract: Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: December 23, 2008
    Assignee: Theravance, Inc.
    Inventors: Donald E. Schmidt, Jr., Jeanmarie Donovan Sganga
  • Process for purifying glycopeptide phosphonate derivatives
    Patent number: 7375181
    Abstract: Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
    Type: Grant
    Filed: December 13, 2005
    Date of Patent: May 20, 2008
    Assignee: Theravance, Inc.
    Inventors: Donald E. Schmidt, Jr., Jeanmarie Donovan Sganga
  • Polyhydroxy glycopeptide derivatives
    Patent number: 6828299
    Abstract: Disclosed are polyhydroxy derivatives of glycopeptides and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: December 7, 2004
    Assignee: Theravance, Inc.
    Inventors: Guang Yang, Donald E. Schmidt, Jr., J. Kevin Judice
  • Multibinding inhibitors of HMG-CoA reductase
    Patent number: 6355810
    Abstract: Disclosed are multibinding compounds which inhibit 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-COA reductase), the rate limiting enzyme in cholesterol biosynthesis. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is a moiety capable of binding to HMG-CoA reductase and the distance between ligands is at least 10 Å. The multibinding compounds of this invention are useful in the treatment and prevention of hypercholesterolemia, hyperlipidemia, atherosclerosis and the like.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: March 12, 2002
    Assignee: Advanced Medicine, Inc.
    Inventors: John H. Griffin, Michael R. Leadbetter, Donald E. Schmidt, Jr.