Patents by Inventor Donald Elbert
Donald Elbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11202701Abstract: A stent for placement in a blood vessel with a wall having an aneurysm including an endovascular graft having a first end, a second end, and a tubular body that is expandable and extends from the first end to the second end. The stent also includes a coagulation apparatus attached to the tubular body between the first and second ends. The coagulation apparatus has a frame and a coagulant attached to the frame. When the stent is deployed within the blood vessel, the tubular body extends across the aneurysm and expands at the first and second ends to seal against the wall of the blood vessel such that blood is channeled across the aneurysm through the tubular body such that a pocket of blood is defined external to the tubular body. The frame expands into the pocket to orient the coagulant therein and promote coagulation of blood within the pocket.Type: GrantFiled: June 30, 2017Date of Patent: December 21, 2021Assignee: Washington UniversityInventors: Eric C. Leuthardt, Greg Zipfel, Colin Derdeyn, Chandu Vemuri, Philip V. Bayly, Guy Genin, Katie McCoy, Junwoo Suh, Yuni Teh, Alan Zhao, Donald Elbert
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Publication number: 20190231513Abstract: A stent for placement in a blood vessel with a wall having an aneurysm including an endovascular graft having a first end, a second end, and a tubular body that is expandable and extends from the first end to the second end. The stent also includes a coagulation apparatus attached to the tubular body between the first and second ends. The coagulation apparatus has a frame and a coagulant attached to the frame. When the stent is deployed within the blood vessel, the tubular body extends across the aneurysm and expands at the first and second ends to seal against the wall of the blood vessel such that blood is channeled across the aneurysm through the tubular body such that a pocket of blood is defined external to the tubular body. The frame expands into the pocket to orient the coagulant therein and promote coagulation of blood within the pocket.Type: ApplicationFiled: June 30, 2017Publication date: August 1, 2019Inventors: Eric C. Leuthardt, Greg Zipfel, Colin Derdeyn, Chandu Vemuri, Philip V. Bayly, Guy Genin, Katie McCoy, Junwoo Suh, Yuni Teh, Alan Zhao, Donald Elbert
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Publication number: 20180372720Abstract: The present disclosure provides for methods or systems for measuring a biomolecule or a therapeutic agent metabolism and determining the biomolecule or therapeutic agent location in a biological sample. Stable Isotope Labeling Kinetics-Secondary Ion Mass Spectrometry (SILK-SIMS) can be utilized for the simultaneous detection, quantification, and imaging of biomolecules or therapeutic agents.Type: ApplicationFiled: June 25, 2018Publication date: December 27, 2018Inventors: Norelle C. Wildburger, Randall J. Bateman, Donald Elbert, Frank Gyngard
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Publication number: 20150004205Abstract: The invention generally relates to surfaces having a protein-resistant hydrogel layer and methods for preparing a protein-resistant hydrogel layer on a surface. The protein-resistant hydrogel layer is formed by a protein-crosslinked water soluble polymer that is contacted with a surface to form a thin protein-resistant hydrogel layer on the surface.Type: ApplicationFiled: June 18, 2014Publication date: January 1, 2015Inventors: Donald Elbert, Megan Kaneda, Evan Scott, Brad Wacker
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Patent number: 8790678Abstract: The invention generally relates to substrates and surfaces having substrates. Generally speaking, the substrates may be thinly layered substrates, and the surfaces may comprise thinly layered substrates. Additionally, the substrates may comprise a multifunctional water soluble polymer and a lipoprotein and the surfaces may comprise a multifunctional water soluble polymer and a lipoprotein.Type: GrantFiled: March 2, 2007Date of Patent: July 29, 2014Assignee: Washington UniversityInventors: Donald Elbert, Megan Kaneda, Evan Scott, Brad Wacker, Shannon Alford
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Patent number: 7744912Abstract: The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.Type: GrantFiled: February 1, 2000Date of Patent: June 29, 2010Assignees: Eidgenossische Technische Hochschule Zurich, Universitat ZurichInventors: Jeffrey A. Hubbell, Donald Elbert, Matthias Lütolf, Alison Pratt, Ronald Schoenmakers, Nicola Tirelli, Brent Vernon
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Publication number: 20090214616Abstract: The invention generally relates to substrates and surfaces having substrates. Generally speaking, the substrates may be thinly layered substrates, and the surfaces may comprise thinly layered substrates. Additionally, the substrates may comprise a multifunctional water soluble polymer and a lipoprotein and the surfaces may comprise a multifunctional water soluble polymer and a lipoprotein.Type: ApplicationFiled: March 2, 2007Publication date: August 27, 2009Applicant: Washington University in St. LouisInventors: Donald Elbert, Megan Kaneda, Evan Scott, Brad Wacker, Shannon Alford
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Publication number: 20090098083Abstract: The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.Type: ApplicationFiled: August 15, 2008Publication date: April 16, 2009Inventors: Jeffrey A. Hubbell, Donald Elbert, Ronald Schoenmakers
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Patent number: 7413739Abstract: The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.Type: GrantFiled: October 25, 2005Date of Patent: August 19, 2008Assignees: Eidgenossische Technische Hochschule Zurich, Universitat ZurichInventors: Jeffrey A. Hubbell, Donald Elbert, Ronald Schoenmakers
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Patent number: 7291673Abstract: The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.Type: GrantFiled: June 4, 2001Date of Patent: November 6, 2007Assignees: Eidgenossiche Technische Hochschule Zurich, Universitat ZurichInventors: Jeffrey A. Hubbell, Donald Elbert, Ronald Schoenmakers
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Publication number: 20070154240Abstract: The present invention relates to conductive adhesives that may be used within an image forming apparatus. The image forming apparatus may include printing devices such as inkjet printers, electrophotographic printers, copiers, faxes, all-in-on devices or multi-functional devices. The conductive resins may be applied to the shaft of foam rolls suitable for transporting and applying image forming material in an image forming apparatus such as a laser printer.Type: ApplicationFiled: December 29, 2005Publication date: July 5, 2007Inventors: Donald Elbert, Jarrett Gayne, David Hullman, Johnny Massie, Michelle Morris, Sean Smith
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Publication number: 20060127352Abstract: The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.Type: ApplicationFiled: October 25, 2005Publication date: June 15, 2006Applicants: Eidgenossische Technische Hochschule Zurich, Universitat ZurichInventors: Jeffrey Hubbell, Donald Elbert, Ronald Schoenmakers
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Publication number: 20060122290Abstract: Compositions for coating biological and non-biological surfaces, which minimize or prevent cell-cell contact and tissue adhesion, and methods of preparation and use thereof, are disclosed. Embodiments include polyethylene glycol/polylysine (PEG/PLL) block or comb-type copolymers with high molecular weight PLL (greater than 1000, more preferably greater than 100,000); PEG/PLL copolymers in which the PLL is a dendrimer which is attached to one end of the PEG; and multilayer compositions including alternating layers of polycationic and polyanionic materials. The multi-layer polymeric material is formed by the ionic interactions of a polycation and a polyanion. The molecular weights of the individual materials are selected such that the PEG portion of the copolymer inhibits cellular interactions, and the PLL portion adheres well to tissues.Type: ApplicationFiled: March 19, 2004Publication date: June 8, 2006Inventors: Jeffrey Hubbell, Donald Elbert, Curtis Herbert
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Publication number: 20060118540Abstract: A semiconductive member has a polymer body filled with carbon black which is surface modified with azo linked organic molecules having an acid functional group. Control of conductivity is greatly improved and the strength of the member is improved by the reduced amount of filler required.Type: ApplicationFiled: December 7, 2004Publication date: June 8, 2006Inventors: Bradley Beach, Donald Elbert, Matthew Houston, Joseph Johnson, Kathryn Mullins, Peter Pickett, John Ringo, Ronald Roe, Jing Sun, Kevin Trembath
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Patent number: 6958212Abstract: The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.Type: GrantFiled: June 2, 2000Date of Patent: October 25, 2005Assignees: Eidgenossische Technische Hochschule Zurich, Univesitat ZurichInventors: Jeffrey A. Hubbell, Donald Elbert, Ronald Schoenmakers
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Publication number: 20030220245Abstract: The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.Type: ApplicationFiled: March 24, 2003Publication date: November 27, 2003Inventors: Jeffrey A Hubbell, Donald Elbert, Ronald Schoenmakers
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Patent number: 5849839Abstract: Described herein is a multi-functional polymeric material for use in inhibiting adhesion and immune recognition between cells and cells, cells and tissues, and tissues and tissues. One component of the polymeric material adsorbs well to cells or tissue, and the other component of the polymeric material does not adsorb well to tissues. A water-soluble polymer that does not bear charge (polynonion) is used as the non-binding component, and a water soluble polymer that is positively charged at physiological pH (polycation) is used as the tissue binding component. When the bi-functional polymeric material contacts a tissue, the tissue-binding component binds and thus immobilizes the attached non-binding component, which will then extend generally away from the tissue surface and sterically block the attachment of other tissues.Type: GrantFiled: March 27, 1997Date of Patent: December 15, 1998Assignee: Board of Regents, The University of Texas SystemInventors: Jeffrey A. Hubbell, Donald Elbert, Jennifer L. Hill-West, Paul D. Drumheller, Sanghamitra Chowdhury, Amarpreet S. Sawhney
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Patent number: 5627233Abstract: Described herein is a multi-functional polymeric material for use in inhibiting adhesion and immune recognition between cells and cells, cells and tissues, and tissues and tissues. One component of the polymeric material adsorbs well to cells or tissue, and the other component of the polymeric material does not adsorb well to tissues. A water-soluble polymer that does not bear charge (polynonion) is used as the non-binding component, and a water soluble polymer that is positively charged at physiological pH (polycation) is used as the tissue binding component. When the bi-functional polymeric material contacts a tissue, the tissue-binding component binds and thus immobilizes the attached non-binding component, which will then extend generally away from the tissue surface and sterically block the attachment of other tissues.Type: GrantFiled: June 6, 1995Date of Patent: May 6, 1997Assignee: Board of Regents, The University of Texas SystemInventors: Jeffrey A. Hubbell, Donald Elbert, Jennifer L. Hill-West, Paul D. Drumheller, Sanghamitra Chowdhury, Amarpreet Sawhney
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Patent number: 5567440Abstract: Described herein is a multi-functional polymeric material for use in inhibiting adhesion and immune recognition between cells and cells, cells and tissues, and tissues and tissues. One component of the polymeric material adsorbs well to cells or tissue, and the other component of the polymeric material does not adsorb well to tissues. A water-soluble polymer that does not bear charge (polynonion) is used as the non-binding component, and a water soluble polymer that is positively charged at physiological pH (polycation) is used as the tissue binding component. When the bi-functional polymeric material contacts a tissue, the tissue-binding component binds and thus immobilizes the attached non-binding component, which will then extend generally away from the tissue surface and sterically block the attachment of other tissues.Type: GrantFiled: June 6, 1995Date of Patent: October 22, 1996Assignee: Board of Regents, The University of Texas SystemInventors: Jeffrey A. Hubbell, Donald Elbert, Jennifer L. Hill-West, Paul D. Drumbeller, Sanghamitra Chowdhury, Amarpreet Sawhney
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Patent number: 5462990Abstract: Described herein is a multi-functional polymeric material for use in inhibiting adhesion and immune recognition between cells and cells, cells and tissues, and tissues and tissues. One component of the polymeric material adsorbs well to cells or tissue, and the other component of the polymeric material does not adsorb well to tissues. A water-soluble polymer that does not bear charge (polynonion) is used as the non-binding component, and a water soluble polymer that is positively charged at physiological pH (polycation) is used as the tissue binding component. When the bi-functional polymeric material contacts a tissue, the tissue-binding component binds and thus immobilizes the attached non-binding component, which will then extend generally away from the tissue surface and sterically block the attachment of other tissues.Type: GrantFiled: October 5, 1993Date of Patent: October 31, 1995Assignee: Board of Regents, The University of Texas SystemInventors: Jeffrey A. Hubbell, Donald Elbert, Jennifer L. Hill-West, Paul D. Drumheller, Sanghamitra Chowdhury, Amarpreet Sawhney