Abstract: The disclosure relates to novel processes for preparing ?-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for preparing said intermediates.

Abstract: Disclosed are processes for preparing ?-carboxamide pyrrolidine derivatives, in particular (2S,5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and intermediates for use in said processes along with processes for preparing said intermediates.

Abstract: The invention relates to a novel process for preparing a-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for preparing said intermediates.

Abstract: The invention relates to a novel process for preparing a-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for preparing said intermediates.

Abstract: The present invention is broadly directed to novel compounds useful for the synthesis of biologically active compounds. More particularly, the present embodiments disclosed herein relate to novel side chains, that when coupled to a taxane, are useful for the synthesis of pharmaceutically useful taxanes. Methods of forming the novel side chains and coupling them to hindered alcohols, namely taxanes resulting in useful esters are also disclosed. Various taxanes compounds are known to exhibit anti-tumor activity.

Abstract: The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification below. The present invention further relates to a process for preparing the compound of formula (II) and novel crystalline structures of the compound of formula (II).

Abstract: The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification below. The present invention further relates to a process for preparing the compound of formula (II) and novel crystalline structures of the compound of formula (II).

Abstract: The present invention is directed to a process for preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof.

Abstract: A distribution system for transferring a plurality of items from a distribution center to a customer comprises a delivery device and a retail device. The delivery device identifies the items and maintains a delivery record of a transfer of the items from the distribution center to the customer. The retail device identifies the items and maintains a receipt record of the transfer of the items. Upon identifying the item, the delivery device displays a description of the item on a display screen, such as the display on a portable computer. The delivery device identifies the items with a barcode scanner. The delivery device also includes a data entry apparatus to enter transfer information, such as an electronically captured signature, into the delivery record.

Abstract: The present invention is directed to a process for preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof.

Abstract: A unitary, rotary encoder disk provides low cost, ease of manufacture, and resolution capability exceeding through hole encoders and, in one embodiment, equivalent to that achieve in thin film technologies. The unitary construct is molded as a transparent polymer disk, with integrated mounting features. Either molded disk surface features or laser burning is used to facilitate the position graduation mark forming process.

Abstract: The present invention is directed to a process for preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof.

Abstract: The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) 1

Abstract: The present invention is directed to a process for preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof.

Abstract: A distribution system for transferring a plurality of items from a distribution center to a customer comprises a delivery device and a retail device. The delivery device identifies the items and maintains a delivery record of a transfer of the items from the distribution center to the customer. The retail device identifies the items and maintains a receipt record of the transfer of the items. Upon identifying the item, the delivery device displays a description of the item on a display screen, such as the display on a portable computer. The delivery device identifies the items with a barcode scanner. The delivery device also includes a data entry apparatus to enter transfer information, such as an electronically captured signature, into the delivery record.

Abstract: An improved camshaft sealing arrangement includes seals at each end of the camshaft housing. In addition, seals and washers are positioned between the camshaft and the slack adjuster connection. The combined seals provide a camshaft that is less likely to require maintenance than prior art camshafts. The seal adjacent the cam contacts an outer periphery of the camshaft housing. This seal also provides a thrust bearing washer surface against the camshaft. The seals between the camshaft and the slack adjuster include washers to properly secure and position the seals, the camshaft and the slack adjuster.

Abstract: A brake lining wear indicator is attached to a drum brake shoe backing plate adjacent the brake lining. The indicator provides a visual gage dimension that assists in the determination of when the brake linings should be replaced. This determination can be made in a very short period of time without requiring a physical measurement of the thickness of the brake lining on each brake shoe.

Abstract: An improved bracket member for a vehicle brake system is disclosed. The bracket member has a wing bracket at one end for mounting of a brake actuating mechanism and a mounting plate at the opposite end for connection to the spider of the brake assembly. A hollow tubular member is positioned between the wing bracket and mounting plate and securely affixed to each of them, such as by welding. The tubular member can be of any length depending on the vehicle and applicable clearance space. The mounting plate is secured such as by fasteners to the brake assembly. Also, the tubular member protrudes through the mounting plate and is adapted to be separately securely connected to the brake assembly. The end of the tubular member can be securely attached to an opening in the brake assembly in a number of ways, such as by an interference fit, press fit, wedge fit, compression fit in combination with a spanner nut, pinch joint or the like. The end of the tubular member can also be knurled or splined.

Abstract: A brake support assembly for a vehicle including a stamped metal spider having a planar mounting portion and a pair of diametrically opposed support portions. A first support portion includes a first pair of ribs extending along opposite edges thereof as involuted ribs. A second support portion includes a second pair of ribs extending along opposite edges thereof to form flanges. A bracket extends across and connects the first pair of ribs. The bracket and the first support portion of the spider include laterally spaced apertures which receive press fit sleeve-type bushings. Anchor pins disposed in said sleeve-type bushings carry one end of a pair of brake shoes each comprised of a pair of spaced generally parallel webs secured to a table. The opposite end of the brake shoes is supported by cam follower rollers. Springs bias the brake shoes into contact with a cam actuator which may be rotated to displace the brake shoes.

Abstract: Processes for the preparation of stable, crystalline cephalosporin intermediates of the formula ##STR1## wherein X is HI or HCl, and Nu and Nu.sup..sym. are certain N-containing heterocyclic rings attached via a sulfur atom or a ring nitrogen atom, respectively, which are substantially free of the .DELTA..sup.2 isomer; processes for intermediates in the preparation of the above compounds; and processes for the preparation of broad-spectrum cephalosporin antibiotics.