Abstract: A suture button system for fixing a syndesmotic injury comprises a flexible fixation implant and an inserter device used to deploy the implant across bones. The flexible fixation implant typically comprises a flexible connector and two suture buttons which interface with the bone surface or a bone plate or washer. The flexible connector comprises a plurality of suture strands. The buttons typically have a feature which allows them to interface with an instrument used to deploy the implant across the two bones. The inserter device is configured to interface with the flexible fixation implant and to position it across bones through a pre-drilled bone tunnel. The inserter device may comprise an cannulated insertion rod and a handle.

Abstract: A suture button system for fixing a syndesmotic injury comprises a flexible fixation implant and an inserter device used to deploy the implant across bones. The flexible fixation implant typically comprises a flexible connector and two suture buttons which interface with the bone surface or a bone plate or washer. The flexible connector comprises a plurality of suture strands. The buttons typically have a feature which allows them to interface with an instrument used to deploy the implant across the two bones. The inserter device is configured to interface with the flexible fixation implant and to position it across bones through a pre-drilled bone tunnel. The inserter device may comprise an cannulated insertion rod and a handle.

Abstract: A suture button system for fixing a syndesmotic injury comprises a flexible fixation implant and an inserter device used to deploy the implant across bones. The flexible fixation implant typically comprises a flexible connector and two suture buttons which interface with the bone surface or a bone plate or washer. The flexible connector comprises a plurality of suture strands. The buttons typically have a feature which allows them to interface with an instrument used to deploy the implant across the two bones. The inserter device is configured to interface with the flexible fixation implant and to position it across bones through a pre-drilled bone tunnel. The inserter device may comprise an cannulated insertion rod and a handle.

Abstract: Systems, methods, and materials are described for making solid unit dosage forms for administration of therapeutic and biotherapeutic agents, particularly dosage forms for various enteral, nasal, pulmonary, vaginal, topical, and other suitable non-injection delivery routes. Contact freezing methods may be used in conjunction with lyophilization or vacuum drying to process a liquid formulation and produce solid unit dosage forms having a high degree of structural stability while preserving the therapeutic activity of the included agents.

Abstract: A detector for detecting generally transparent or translucent items for a high speed filling machine. The detector includes an infrared emitter emitting infrared light in a range of 1300 nm to 1600 nm or 1800 nm to 2200 nm and an infrared sensor for detecting infrared light in the selected ranges.

Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.

Abstract: A microscale fluid delivery system has a method of addition and removal of fluids to the internals of solids is in an enclosed system. The system includes a processing chamber comprising the steps of submerging the object within the chamber in a fluid, isolating the chamber, reducing the pressure to form vapor bubbles on the object's internal surfaces, increasing the pressure to introduce fluid to the object's internal surfaces, and repeating the decrease and increase in pressure until the object is fully processed.

Abstract: Described are vaccine regimens in which specific prime/boost regimens are applied using low-neutralized recombinant adenoviral vectors harboring nucleic acids encoding antigens from Plasmodium falciparum and purified recombinant protein vaccines such as RTS,S, in the context of appropriate adjuvants.

Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.

Abstract: Parts to be chemically treated are processed in a controlled-environment processing chamber. The process includes applying a negative gauge pressure to the chamber to remove air or other non-condensable gases. The process includes introducing an oxygen free solvent or aqueous solution in a vapor or liquid state. A first system removes oxygen and volatile contaminants from the object being processed and chamber, and a second system further recovers residual solvent from the object and chamber. Eliminating oxygen from the process prevents deflagration within the system thus allowing for the use of flammable solvents within the process.

Abstract: Parts to be chemically treated are processed in a controlled-environment processing chamber. The process includes a means of applying a negative gauge pressure to the chamber to remove air or other non-condensable gases. Means are provided for introducing an oxygen free solvent or aqueous solution in a vapor or liquid state. A first system removes oxygen and volatile contaminants from the object being processed and chamber, and a second system further recovers residual solvent from the object and chamber. Eliminating oxygen from the process prevents deflagration within the system thus allowing for the use of flammable solvents within the process.

Abstract: An enhanced Vacuum Cavitational Streaming (VCS) process focuses on the formation of vapor bubbles and the transfer of a chemical from the solvent to the surface of the object while the chemical is in the vapor state within the bubble, i.e. a chemical mechanism. There is less importance on the rapid implosion (physical mechanism) of the bubble, and more focus on the controlled formation and collapse (as opposed to implosion) of the vapor bubble.

Abstract: Systems and methods for providing resource management in a distributed network are disclosed. A loose collection of devices in a network may not be aware of the power restrictions for other devices. Wall powered devices will generally have drastically different power settings than battery powered mobile devices. The invention provides a federation policy for time that can be used to slave to a local service responsible for understanding the local resource requirements of each device (or node) on the network. In such a distributed time system, all services in a particular time domain may be sped up, slowed down, or completely halted.

Abstract: A radio module that detachably connects with a host device. A radio module is provided that includes an antenna as an integral part of the radio module. The antenna satisfies regulatory requirements by being an integral part of the radio module. The radio module includes an interface circuit that provides the processing required for communication over a wireless network. The functionality of the interface can be divided between the radio module and the host device. The physical interface between a host device and the radio module may depend on which functions are implemented by the radio module and which functions are implemented by the host device. In one example, the physical interface is a standard connection that permits the radio module to be detachably connected with multiple devices. The radio module also includes a flexible cable such that the radio module can be optimally positioned within the wireless network.

Abstract: A radio module that detachably connects with a host device. A radio module is provided that includes an antenna as an integral part of the radio module. The antenna satisfies regulatory requirements by being an integral part of the radio module. The radio module includes an interface circuit that provides the processing required for communication over a wireless network. The functionality of the interface can be divided between the radio module and the host device. The physical interface between a host device and the radio module may depend on which functions are implemented by the radio module and which functions are implemented by the host device. In one example, the physical interface is a standard connection that permits the radio module to be detachably connected with multiple devices. The radio module also includes a flexible cable such that the radio module can be optimally positioned within the wireless network.

Abstract: Real-time communication of multimedia data over heterogeneous networks that may include constant delay networks, variable delay networks that have a common reckoning of time, and variable delay networks that do not have a common reckoning of time. If there are any variable delay networks in which there is no common reckoning of time in the heterogeneous networks, a common reckoning of time is established in each of those networks. Then, a constant delay network is emulated for each variable delay network using the specific common time reckoning present in each variable delay network.

Abstract: Methods and systems for preventing unacceptable communication requests from being transmitted to a network-accessible service are disclosed. A domain name server for a local network including a network-accessible service returns an address for a network security system remote from the local network in response to a request for the address of the network-accessible service. The network security system processes communication requests directed to the network-accessible service to determine whether the communication request is a network intrusion attempt. If so, the network security system performs a network intrusion prevention technique, such as discarding the communication request, generating an alert or message or storing at least a portion of the communication request. Otherwise, the network security system forwards the communication request to the network-accessible service.

Abstract: Systems for servicing the data and memory requirements of system devices. A DMA engine that includes a data reservoir is provided that manages and arbitrates the data requests from the system devices. An arbitration unit is provided that only allows eligible devices to make a data request in any given cycle to ensure that all devices will be serviced within a programmable time period. The data reservoir contains the data buffers for each channel of each device. A memory interface ensures that sufficient data for each channel is present in the data reservoir by making requests to a system's memory based on an analysis of each channel. Based on this analysis, a request is either made to the system's main memory, or the channel waits until it is evaluated again in the future. Each channel is thereby guaranteed a response time.

Abstract: Systems for servicing the data and memory requirements of system devices. A DMA engine that includes a data reservoir is provided that manages and arbitrates the data requests from the system devices. An arbitration unit is provided that only allows eligible devices to make a data request in any given cycle to ensure that all devices will be serviced within a programmable time period. The data reservoir contains the data buffers for each channel of each device. A memory interface ensures that sufficient data for each channel is present in the data reservoir by making requests to a system's memory based on an analysis of each channel. Based on this analysis, a request is either made to the system's main memory, or the channel waits until it is evaluated again in the future. Each channel is thereby guaranteed a response time.

Abstract: Systems and methods for compositing an image directly from multiple source image data for reducing system memory footprint and bandwidth and for improving color quality of the image. The image is divided into spans, lines, and slices. Each line includes at least one span and each slice includes at least one line. All lines in a slice have spans associated with identical sources. An image is composited by reading the image data directly from one or more sources of each span. If necessary, the sources are blended. A control structure is used to provide the image context and identifies the sources of the spans. The control structure includes headers for each data stream from each source of each span. Also, the color quality of the image is improved by reducing the number of color space conversions that occur as the image is composited. All sources in the same color space are blended, before being blended with sources from other color spaces. Preferably, no more than a single color conversion is required.