Abstract: An antimicrobial composition includes peracetic acid and witch hazel extract. The peracetic acid can be formed by combining and reacting the acetic acid and hydrogen peroxide, for example at the point of use. Alternatively, the peracetic acid may be formed separately and mixed with the witch hazel extract prior to use. The resulting peracetic acid and hydrogen peroxide are, thus, combined with the witch hazel extract prior to use. The combination of peracetic acid, hydrogen peroxide and witch hazel extract may be applied as an antimicrobial. The antimicrobial composition may be applied topically to various organs (e.g., skin, nose, ears, mouth, throat, urethra, urinary bladder, gastrointestinal organs) or instilled through an indwelling urinary catheter or applied or inserted as a topical additive or coating to devices or other organ surfaces or other medical devices, or on the skin of the body or surfaces of inanimate objects.

Abstract: An antimicrobial composition includes an aqueous and/or ethanolic solution of iodine and hydrogen peroxide, which is acidified. The acidifying agent may be aspirin, hydrochloric acid, or other acidic agent tolerable to the body. The composition may also include a witch hazel extract, or alternately hamamelitannin, gallic acid, or other components thereof that effect quorum signaling inhibition that blocks and erodes microbe-induced biofilm on cellular and device surfaces. Acetohydroxamic acid may be combined with the composition as a counter to microbe-induced alkalinization, particularly in urine. Moreover, a metal, halogen, and combinations of these, such as a silver colloid, may be added as a secondary microbicidal agent. The antimicrobial composition may be applied topically to or instilled through an indwelling urinary catheter or applied as a device surface-coating on other medical devices.

Abstract: An antimicrobial composition includes an organic extract, such as a witch hazel extract, and a colloid selected from metal, halogen, and combinations of these, such as a silver colloid. The witch hazel extract includes tannins in excess of about 10 mg/ml, such as hamamelitannin, and the colloid includes about 10,000 PPM of metal, such as silver. The antimicrobial composition may be applied to or instilled through an indwelling urinary catheter or other medical device.

Abstract: A device for snugging a balloon of a catheter against an inner wall of an intra-corporeal lumen or surface serviced by the catheter includes a hollow column having a top end and a bottom end, forming a throughway sized to accommodate a tube of the catheter, and a flange extending from the bottom end of the hollow column generally perpendicularly to length of the hollow column. A slit is formed in the hollow column and the flange through which the hollow column is connectable to the tube of the catheter. The catheter is tugged to contact the balloon to the inner wall of the lumen, and the device is fixed to the tube of the catheter atop the skin of a body serviced by the catheter to tension pressure of the balloon against the inner wall.

Abstract: A device for snugging a balloon of a catheter against an inner wall of an intra-corporeal lumen or surface serviced by the catheter includes a hollow column having a top end and a bottom end, forming a throughway sized to accommodate a tube of the catheter, and a flange extending from the bottom end of the hollow column generally perpendicularly to length of the hollow column. A slit is formed in the hollow column and the flange through which the hollow column is connectable to the tube of the catheter. The catheter is tugged to contact the balloon to the inner wall of the lumen, and the device is fixed to the tube of the catheter atop the skin of a body serviced by the catheter to tension pressure of the balloon against the inner wall.

Abstract: A tissue bonding implantation device includes an internal drainage tube having an internal surface and an external surface, an inflatable balloon in the shape of a toroid encircling the outer surface of the internal drainage tube, and a balloon inflation conduit in fluid communication with an interior of the inflatable balloon. A transcutaneous sleeve in the form of a tube having an internal diameter allows the sleeve to fit over the external surface of the internal drainage tube, and the sleeve includes a horizontal flange positioned at a top edge of the sleeve. The horizontal flange lies flat on the skin surface. An external cap has a first sealable opening in fluid communication with the internal drainage tube and a second sealable opening in fluid communication with the balloon inflation conduit extending from the balloon to the cap proximate to the sleeve. A tissue-bonding anchor is reversibly attached onto the outer surface of the drainage tube in a watertight manner, via the inflatable balloon.

Abstract: A device for snugging a balloon of a catheter against an inner wall of an intra-corporeal lumen or surface serviced by the catheter includes a hollow column having a top end and a bottom end, forming a throughway sized to accommodate a tube of the catheter, and a flange extending from the bottom end of the hollow column generally perpendicularly to length of the hollow column. A slit is formed in the hollow column and the flange through which the hollow column is connectable to the tube of the catheter. The catheter is tugged to contact the balloon to the inner wall of the lumen, and the device is fixed to the tube of the catheter atop the skin of a body serviced by the catheter to tension pressure of the balloon against the inner wall.

Abstract: A tissue bonding implantation device includes an internal drainage tube having an internal surface and an external surface, an inflatable balloon in the shape of a toroid encircling the outer surface of the internal drainage tube, and a balloon inflation conduit in fluid communication with an interior of the inflatable balloon. A transcutaneous sleeve in the form of a tube having an internal diameter allows the sleeve to fit over the external surface of the internal drainage tube, and the sleeve includes a horizontal flange positioned at a top edge of the sleeve.

Abstract: A cystostomy device for implant in a patient includes a transcutaneous sleeve a flange connected to the transcutaneous sleeve, adapted to reduce contamination of an outer surface of said transcutaneous sleeve, a catheter defining a passage for the flow of fluids from within the patient to outside the patient, an inner surface of the transcutaneous sleeve defining a path through which the catheter passes, and an anchor adapted for implantation into the biological tissue of the patient, the anchor connecting to the catheter and the transcutaneous sleeve. At least one microbe resistance zone is included on surfaces in any of the sleeve, the flange, and the catheter. The microbe resistance zone may be formed on the surfaces of the sleeve, flange and catheter, or may be adhered to the device as tape that may be rolled. A micropore filter prevents back flow of urine from a urinary bag.

Abstract: A tissue bonding implantation device includes an internal drainage tube having an internal surface and an external surface, an inflatable balloon in the shape of a toroid encircling the outer surface of the internal drainage tube, and a balloon inflation conduit in fluid communication with an interior of the inflatable balloon. A transcutaneous sleeve in the form of a tube having an internal diameter allows the sleeve to fit over the external surface of the internal drainage tube, and the sleeve includes a horizontal flange positioned at a top edge of the sleeve.